(Q34288280)

1 August 2017

title

Selective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathways (English)

1 reference

ubiquitin-proteasome system

1 August 2017

main subject

0 references

author name string

Huali Zhang

1

1 reference

1 August 2017

Namakkal S Rajasekaran

2

1 reference

1 August 2017

Andras Orosz

3

1 reference

1 August 2017

Xianzhong Xiao

4

1 reference

1 August 2017

Martin Rechsteiner

5

1 reference

1 August 2017

Ivor J Benjamin

6

1 reference

1 August 2017

publication date

21 September 2010

1 reference

Journal of Molecular and Cellular Cardiology

1 August 2017

published in

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1 August 2017

volume

49

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1 August 2017

issue

6

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1 August 2017

page(s)

918-930

1 reference

Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function

1 August 2017

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Single molecule force spectroscopy of the cardiac titin N2B element: effects of the molecular chaperone alphaB-crystallin with disease-causing mutations

6 July 2018

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6 July 2018

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Autophagy-mediated clearance of aggresomes is not a universal phenomenon

6 July 2018

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Truncation of alphaB-crystallin by the myopathy-causing Q151X mutation significantly destabilizes the protein leading to aggregate formation in transfected cells

6 July 2018

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Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic

6 July 2018

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Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice

6 July 2018

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HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells

6 July 2018

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Small heat shock proteins: molecular structure and chaperone function

6 July 2018

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Modulation of neurodegeneration by molecular chaperones

6 July 2018

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

6 July 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

6 July 2018

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6 July 2018

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HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation

6 July 2018

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Distinct chaperone mechanisms can delay the formation of aggresomes by the myopathy-causing R120G alphaB-crystallin mutant

6 July 2018

1 reference

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Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

6 July 2018

1 reference

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

6 July 2018

1 reference

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Heat shock factor 1 and heat shock proteins: critical partners in protection against acute cell injury

6 July 2018

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Alpha-B crystallin gene (CRYAB) mutation causes dominant congenital posterior polar cataract in humans

6 July 2018

1 reference

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The cardiomyopathy and lens cataract mutation in alphaB-crystallin alters its protein structure, chaperone activity, and interaction with intermediate filaments in vitro.

6 July 2018

1 reference

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Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

6 July 2018

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6 July 2018

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A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

6 July 2018

1 reference

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Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

6 July 2018

1 reference

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3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

6 July 2018

1 reference

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Lens crystallins and their genes: diversity and tissue-specific expression

6 July 2018

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Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant.

6 July 2018

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Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake

28 October 2018

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Myofibrillar myopathy caused by novel dominant negative alpha B-crystallin mutations.

28 October 2018

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Hsp27 suppresses the formation of inclusion bodies induced by expression of R120G alpha B-crystallin, a cause of desmin-related myopathy.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2975794

Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

28 October 2018

1 reference

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Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

28 October 2018

1 reference

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Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats

28 October 2018

1 reference

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Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease

28 October 2018

1 reference

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Structural and functional consequences of the mutation of a conserved arginine residue in alphaA and alphaB crystallins

28 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.09.004

Expression of R120G-alphaB-crystallin causes aberrant desmin and alphaB-crystallin aggregation and cardiomyopathy in mice

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.09.004

Myopathy-associated alphaB-crystallin mutants: abnormal phosphorylation, intracellular location, and interactions with other small heat shock proteins

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2010.09.004

10.1016/J.YJMCC.2010.09.004

7 January 2021

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference