(Q34325514)

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Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway

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Europe PubMed Central

PubMed publication ID

1 August 2017

Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway (English)

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Europe PubMed Central

PubMed publication ID

1 August 2017

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Jongkyeong Chung

8

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Jongkyeong Chung

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Europe PubMed Central

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1 August 2017

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Jun Hee Lee

1

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Europe PubMed Central

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1 August 2017

Kyoung Sang Cho

2

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1 August 2017

Jihyun Lee

3

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Europe PubMed Central

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1 August 2017

Dohoon Kim

4

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Europe PubMed Central

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1 August 2017

Sung-Bae Lee

5

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1 August 2017

Jungsik Yoo

6

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1 August 2017

Guang-Ho Cha

7

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1 August 2017

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1 November 2002

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1 August 2017

Molecular and Cellular Biology

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1 August 2017

22

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1 August 2017

21

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Europe PubMed Central

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1 August 2017

7658-7666

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation

1 reference

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Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway.

1 reference

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Rap1 signalling: adhering to new models

1 reference

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Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction

1 reference

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The guanine nucleotide exchange factor CNrasGEF activates ras in response to cAMP and cGMP

1 reference

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Mutations modulating the Argos-regulated signaling pathway in Drosophila eye development

1 reference

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The genome sequence of Drosophila melanogaster

1 reference

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PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

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RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

1 reference

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6 July 2018

Ras and Rap1: two highly related small GTPases with distinct function

1 reference

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nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM)

1 reference

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A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.

1 reference

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The gene search system. A method for efficient detection and rapid molecular identification of genes in Drosophila melanogaster

1 reference

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The Rap1 GTPase functions as a regulator of morphogenesis in vivo

1 reference

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Activation of the Drosophila C3G leads to cell fate changes and overproliferation during development, mediated by the RAS-MAPK pathway and RAP1.

1 reference

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6 July 2018

A family of cAMP-binding proteins that directly activate Rap1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

6 July 2018

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

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6 July 2018

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

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A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

1 reference

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6 July 2018

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

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Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

6 July 2018

Genetic interactions with Rap1 and Ras1 reveal a second function for the Fat facets deubiquitinating enzyme in Drosophila eye development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

6 July 2018

Coassociation of Rap1A and Ha-Ras with Raf-1 N-terminal region interferes with ras-dependent activation of Raf-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

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cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

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Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

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Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=135652

6 July 2018

A protein kinase similar to MAP kinase activator acts downstream of the raf kinase in Drosophila

1 reference

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RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

1 reference

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The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway.

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A ras-related gene with transformation suppressor activity

1 reference

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1 reference

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The single-minded gene of Drosophila is required for the expression of genes important for the development of CNS midline cells

1 reference

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The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination

1 reference

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A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

1 reference

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The Son of sevenless Gene Product: a Putative Activator of Ras

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Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

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Ras1 promotes cellular growth in the Drosophila wing

1 reference

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12 December 2020

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10.1128/MCB.22.21.7658-7666.2002

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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