(Q34350044)

English

Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model

scientific article

In more languages

default for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Expanded ataxin-7 cause toxicity by inducing ROS production from NADPH oxidase complexes in a stable inducible Spinocerebellar ataxia type 7 (SCA7) model (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

spinocerebellar ataxia type 7

1 reference

based on heuristic

inferred from title

4

object named as

Ulo Langel

0 references

author name string

Abiodun Ajayi

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Xin Yu

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Staffan Lindberg

3

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Ulo Langel

4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Anna-Lena Ström

5

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

publication date

24 July 2012

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

BMC Neuroscience

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

86

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Mitochondrial dysfunction, metabolic deficits, and increased oxidative stress in Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Early and late events induced by polyQ-expanded proteins: identification of a common pathogenic property of polYQ-expanded proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Protein oxidative modifications in the ageing brain: Consequence for the onset of neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Neurotoxic protein oligomerisation associated with polyglutamine diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Downregulation of NF-kappaB signaling by mutant huntingtin proteins induces oxidative stress and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Oxidative stress in neurodegeneration and available means of protection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Reconciling the chemistry and biology of reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Oxidative stress and neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Polyglutamine diseases: emerging concepts in pathogenesis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Huntingtin inclusion bodies are iron-dependent centers of oxidative events.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Oxidative stress promotes mutant huntingtin aggregation and mutant huntingtin-dependent cell death by mimicking proteasomal malfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

A role for both wild-type and expanded ataxin-7 in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Glutathione transferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Protein aggregation and neurodegenerative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Glutathione depletion and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

The olivopontocerebellar atrophies: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

A direct demonstration of the catalytic action of superoxide dismutase through the use of pulse radiolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

6 July 2018

Expression of ataxin-7 in CNS and non-CNS tissue of normal and SCA7 individuals

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Molecular Genetics and Biomarkers of Polyglutamine Diseases

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Human retinoic acid receptor-related orphan receptor alpha1 overexpression protects neurones against oxidative stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Variation in the biochemical/biophysical properties of mutant superoxide dismutase 1 enzymes and the rate of disease progression in familial amyotrophic lateral sclerosis kindreds.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2202-13-86

21 January 2018

Oxidative stress in neurodegeneration in dentatorubral-pallidoluysian atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3412756

27 October 2018

On an autosomal dominant form of retinal-cerebellar degeneration: an autopsy study of five patients in one family

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear inclusions in Huntington's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression analysis of ataxin-7 mRNA and protein in human brain: evidence for a widespread distribution and focal protein accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of human A4V mutant Cu,Zn superoxide dismutase in Schizosaccharomyces pombe: investigations of its toxic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of ataxin-7 in normal human brain and retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/22827889

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1471-2202-13-86

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34350044&oldid=2196536306"