(Q34354862)

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Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors

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1 August 2017

Brief report: a human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors (English)

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1 August 2017

Human Induced Pluripotent Stem Cells

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Jumana Yousuf Al-Aama

5

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Jumana Yousuf Al-Aama

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Irina Neganova

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1 August 2017

Miodrag Stojkovic

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Miodrag Stojkovic

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1 August 2017

author name string

Katarzyna Tilgner

1

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1 August 2017

Chatchawan Singhapol

3

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1 August 2017

Gabriele Saretzki

4

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1 August 2017

Jumana Yousuf Al-Aama

5

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1 August 2017

Jerome Evans

6

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1 August 2017

Vera Gorbunova

7

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1 August 2017

Andrew Gennery

8

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1 August 2017

Stefan Przyborski

9

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1 August 2017

Lyle Armstrong

11

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1 August 2017

Penny Jeggo

12

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1 August 2017

Majlinda Lako

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1 August 2017

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publication date

1 September 2013

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1 August 2017

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1 August 2017

31

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1 August 2017

9

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2015-2023

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1 August 2017

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

DNA double-strand break repair: all's well that ends well

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https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Nonhomologous end joining and V(D)J recombination require an additional factor

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Cernunnos interacts with the XRCC4 x DNA-ligase IV complex and is homologous to the yeast nonhomologous end-joining factor Nej1.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

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https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Length-dependent binding of human XLF to DNA and stimulation of XRCC4.DNA ligase IV activity

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends

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https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

DNA repair is limiting for haematopoietic stem cells during ageing

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Requirement for DNA ligase IV during embryonic neuronal development

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Hematopoietic cytokines, transcription factors and lineage commitment

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1456

21 January 2018

Identifiers

10.1002/STEM.1456

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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