(Q34356166)

1 August 2017

title

Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer (English)

1 reference

Natalie Louise Stephenson

1 August 2017

1 reference

4

object named as

Natalie L Stephenson

1 reference

1 August 2017

Crispin J Miller

10

0 references

author name string

Shameem Fawdar

1

1 reference

1 August 2017

Eleanor W Trotter

2

1 reference

1 August 2017

Yaoyong Li

3

1 reference

1 August 2017

Franziska Hanke

5

1 reference

1 August 2017

Anna A Marusiak

6

1 reference

1 August 2017

Zoe C Edwards

7

1 reference

1 August 2017

Sara Ientile

8

1 reference

1 August 2017

Bohdan Waszkowycz

9

1 reference

1 August 2017

John Brognard

11

1 reference

1 August 2017

language of work or name

English

0 references

publication date

8 July 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

1 August 2017

volume

110

1 reference

1 August 2017

issue

30

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1 August 2017

page(s)

12426-12431

1 reference

Genes responsible for the characteristics of primary cultured invasive phenotype hepatocellular carcinoma cells

1 August 2017

cites work

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6 July 2018

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The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer

6 July 2018

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

6 July 2018

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

6 July 2018

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Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer

6 July 2018

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Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

6 July 2018

1 reference

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Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity

6 July 2018

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TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway

6 July 2018

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Illustration of SSMD, z score, SSMD*, z* score, and t statistic for hit selection in RNAi high-throughput screens

6 July 2018

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Cancer-associated loss-of-function mutations implicate DAPK3 as a tumor-suppressing kinase

6 July 2018

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ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time

6 July 2018

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RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

6 July 2018

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

6 July 2018

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Epidermal growth factor receptor inhibition in lung cancer: the evolving role of individualized therapy

6 July 2018

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Somatic EGFR mutation and gene copy gain as predictive biomarkers for response to tyrosine kinase inhibitors in non-small cell lung cancer

6 July 2018

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Statistical methods for analysis of high-throughput RNA interference screens

6 July 2018

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UnPAKing the class differences among p21-activated kinases

6 July 2018

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p21 activated kinase 5 activates Raf-1 and targets it to mitochondria

6 July 2018

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Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

6 July 2018

1 reference

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A new method with flexible and balanced control of false negatives and false positives for hit selection in RNA interference high-throughput screening assays

6 July 2018

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Patterns of somatic mutation in human cancer genomes

6 July 2018

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Oncogenic re-wiring of cellular signaling pathways

6 July 2018

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A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays

6 July 2018

1 reference

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Distinguishing cancer-associated missense mutations from common polymorphisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3725071

siRNA in human cells selectively localizes to target RNA sites

6 July 2018

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GROMACS: fast, flexible, and free

6 July 2018

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Cellular signaling by fibroblast growth factor receptors

6 July 2018

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An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division

6 July 2018

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

6 July 2018

1 reference

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Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

6 July 2018

1 reference

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Mixed-lineage kinase control of JNK and p38 MAPK pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3725071

Activated PAK4 regulates cell adhesion and anchorage-independent growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3725071

From cancer genomes to oncogenic drivers, tumour dependencies and therapeutic targets

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1305207110

ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1305207110

Clinical features of 5,628 primary lung cancer patients: experience at Mayo Clinic from 1997 to 2003

21 January 2018

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PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mixed lineage kinase inhibitor CEP-1347 fails to delay disability in early Parkinson disease.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23836671

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1305207110

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference