(Q34386573)

1 August 2017

Genome mining of Streptomyces ambofaciens. (English)

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1 August 2017

Streptomyces ambofaciens

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Streptomyces murayamaensis

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DPBGKPFDZAMRAC-OXEVIEKESA-N

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[(1R,2S,3S,4S)-2,4-diacetyloxy-5-cyano-3,7-dihydroxy-3-methyl-6,11-dioxo-2,4-dihydro-1H-benzo[b]carbazol-1-yl] acetate

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KDNCTFOFNDNJHH-CVKRWWMHSA-N

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VGGKBFRLUHMBGC-FJABJUAASA-N

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SZXUZQODGAKEAQ-CYDBFPOJSA-N

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1 reference

1

Bertrand Aigle

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1 August 2017

Sylvie Lautru

2

0 references

Pierre Leblond

Pierre Leblond

6

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Jean-Luc Pernodet

Jean-Luc Pernodet

7

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Gregory L. Challis

Gregory L Challis

5

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Jeroen S. Dickschat

4

Jeroen S Dickschat

1 reference

1 August 2017

Dieter Spiteller

3

1 reference

1 August 2017

21 November 2013

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PubMed ID

24258629

full work available at URL

1 August 2017

https://academic.oup.com/jimb/article-pdf/41/2/251/36813574/jimb0251.pdf

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19 March 2024

https://api.unpaywall.org/v2/10.1007/s10295-013-1379-y?email=unpaywall_01@example.com

published in

Journal of Industrial Microbiology & Biotechnology

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1 August 2017

41

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1 August 2017

251-263

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1 August 2017

2

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https://api.unpaywall.org/v2/10.1007/s10295-013-1379-y?email=unpaywall_01@example.com

1 August 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

inferred from online access status

cites work

Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors.

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Identification of a cluster of genes that directs desferrioxamine biosynthesis in Streptomyces coelicolor M145.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Regulation of the synthesis of the angucyclinone antibiotic alpomycin in Streptomyces ambofaciens by the autoregulator receptor AlpZ and its specific ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Characterization and manipulation of the pathway-specific late regulator AlpW reveals Streptomyces ambofaciens as a new producer of Kinamycins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Terpenoids are widespread in actinomycetes: a correlation of secondary metabolism and genome data

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Characterization of a novel regulatory gene governing the expression of a polyketide synthase gene in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Streptomyces coelicolor as an expression host for heterologous gene clusters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Kinamycins A and C, bacterial metabolites that contain an unusual diazo group, as potential new anticancer agents: antiproliferative and cell cycle effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

An iterative nonribosomal peptide synthetase assembles the pyrrole-amide antibiotic congocidine in Streptomyces ambofaciens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

From bacteria to antineoplastic: epothilones a successful history.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

SEARCHGTr: a program for analysis of glycosyltransferases involved in glycosylation of secondary metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Regulation of the biosynthesis of the macrolide antibiotic spiramycin in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

A tylosin ketoreductase reveals how chirality is determined in polyketides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Thiostrepton biosynthesis: prototype for a new family of bacteriocins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Production of a novel polyketide through the construction of a hybrid polyketide synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Roles of rapH and rapG in positive regulation of rapamycin biosynthesis in Streptomyces hygroscopicus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

The albonoursin gene Cluster of S noursei biosynthesis of diketopiperazine metabolites independent of nonribosomal peptide synthetases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Automated genome mining for natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Use and Discovery of Chemical Elicitors That Stimulate Biosynthetic Gene Clusters in Streptomyces Bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Glycosylation steps during spiramycin biosynthesis in Streptomyces ambofaciens: involvement of three glycosyltransferases and their interplay with two auxiliary proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Kinamycin F downregulates cyclin D3 in human leukemia K562 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Concentrations and in vivo antibacterial activity of spiramycin and metronidazole in patients with periodontitis treated with high-dose metronidazole and the spiramycin/metronidazole combination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

A new shuttle cosmid vector, pKC505, for streptomycetes: its use in the cloning of three different spiramycin-resistance genes from a Streptomyces ambofaciens library

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

An unprecedented 1,2-shift in the biosynthesis of the 3-aminosalicylate moiety of antimycins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

A single Streptomyces symbiont makes multiple antifungals to support the fungus farming ant Acromyrmex octospinosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Cloning of the netropsin resistance genes from Streptomyces flavopersicus NRRL 2820.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

The regulation of the secondary metabolism of Streptomyces: new links and experimental advances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Cyanobacteria as a source of natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

SEARCHPKS: A program for detection and analysis of polyketide synthase domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10295-013-1379-Y

Genetic instability and associated genome plasticity in Streptomyces ambofaciens: pulsed-field gel electrophoresis evidence for large DNA alterations in a limited genomic region

21 January 2018

1 reference

12 December 2020

Increasing the efficiency of heterologous promoters in actinomycetes

1 reference

12 December 2020

Triggers and cues that activate antibiotic production by actinomycetes

1 reference

12 December 2020

[A new species of Streptomyces producing antibiotics Streptomyces ambofaciens n. sp., cultural characteristics].

1 reference

12 December 2020

Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways

1 reference

12 December 2020

Volatile lactones from streptomycetes arise via the antimycin biosynthetic pathway

1 reference

12 December 2020

Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase

1 reference

12 December 2020

Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2.

1 reference

12 December 2020

Cloning and heterologous expression of genes from the kinamycin biosynthetic pathway of Streptomyces murayamaensis

1 reference

12 December 2020

Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements

1 reference

12 December 2020

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

1 reference

12 December 2020

A chain initiation factor common to both modular and aromatic polyketide synthases

1 reference

12 December 2020

[Trypanocide action of an antibiotic produced by a Streptomyces]

1 reference

12 December 2020

A Sweet Origin for the Key Congocidine Precursor 4-Acetamidopyrrole-2-carboxylate

1 reference

12 December 2020

Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?

1 reference

12 December 2020

Cloning of spiramycin biosynthetic genes and their use in constructing Streptomyces ambofaciens mutants defective in spiramycin biosynthesis

1 reference

12 December 2020

Evolution of the terminal regions of the Streptomyces linear chromosome

1 reference

12 December 2020

Biosynthesis of the Kinamycins

1 reference

12 December 2020

10.1007/S10295-013-1379-Y

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

24258629