(Q34390370)

English

Taxane pathway

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

1 August 2017

Taxane pathway (English)

1 reference

Europe PubMed Central

1 August 2017

6

object named as

Russ Altman

1 reference

Europe PubMed Central

1 August 2017

Michelle Whirl-Carrillo

4

object named as

Michelle Whirl Carrillo

1 reference

Europe PubMed Central

1 August 2017

author name string

Connie Oshiro

1

1 reference

Europe PubMed Central

1 August 2017

Sharon Marsh

2

1 reference

Europe PubMed Central

1 August 2017

Howard McLeod

3

1 reference

Europe PubMed Central

1 August 2017

Teri Klein

5

1 reference

Europe PubMed Central

1 August 2017

publication date

1 December 2009

1 reference

Europe PubMed Central

1 August 2017

Pharmacogenetics and Genomics

1 reference

Europe PubMed Central

1 August 2017

19

1 reference

Europe PubMed Central

1 August 2017

979-983

1 reference

Europe PubMed Central

1 August 2017

12

1 reference

Europe PubMed Central

1 August 2017

Chromosomal instability determines taxane response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Nuclear receptor mediated induction of cytochrome P450 3A4 by anticancer drugs: a key role for the pregnane X receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Randomized crossover pharmacokinetic study of solvent-based paclitaxel and nab-paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Pharmacogenetic pathway analysis of docetaxel elimination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Taxanes, microtubules and chemoresistant breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Taxol-resistance-associated gene-3 (TRAG-3/CSAG2) expression is predictive for clinical outcome in ovarian carcinoma patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Association of ABCB1 genotypes with paclitaxel-mediated peripheral neuropathy and neutropenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

mdr-1 single nucleotide polymorphisms in ovarian cancer tissue: G2677T/A correlates with response to paclitaxel chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Pharmacokinetics of paclitaxel in ovarian cancer patients and genetic polymorphisms of CYP2C8, CYP3A4, and MDR1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Targeting microtubules for cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Preclinical pharmacology of the taxanes: implications of the differences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Effect of cytochrome P450 3A4 inhibition on the pharmacokinetics of docetaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Microtubules as a target for anticancer drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Taxane-based reversal agents modulate drug resistance mediated by P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Pharmacological effects of formulation vehicles : implications for cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

New insights in beta-tubulin sequence analysis in non-small cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Mutational analysis of the class I beta-tubulin gene in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Influence of Cremophor El on the bioavailability of intraperitoneal paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Mutational analysis of the beta-tubulin gene in lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Refined structure of alpha beta-tubulin at 3.5 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Cremophor EL: the drawbacks and advantages of vehicle selection for drug formulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Role of formulation vehicles in taxane pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Paclitaxel resistance in non-small-cell lung cancer associated with beta-tubulin gene mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Clinical pharmacokinetics of docetaxel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

A phase II study of docetaxel in patients with paclitaxel-resistant metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Induction of broad drug resistance in small cell lung cancer cells and its reversal by paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Multiple forms of tubulin: different gene products and covalent modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Inactivation of Bcl-2 by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

Taxanes: a new class of antitumor agents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

6 July 2018

The roles of beta-tubulin mutations and isotype expression in acquired drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Genetic polymorphisms affecting clinical outcomes in epithelial ovarian cancer patients treated with taxanes and platinum compounds: a Korean population-based study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Pharmacogenetic studies of Paclitaxel in the treatment of ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Variants in the SLCO1B3 gene: interethnic distribution and association with paclitaxel pharmacokinetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Genetic variation in ABCB1 influences paclitaxel pharmacokinetics in Japanese patients with ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

beta-Tubulin mutations in ovarian cancer using single strand conformation analysis-risk of false positive results from paraffin embedded tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Mutation of the class I beta-tubulin gene does not predict response to paclitaxel for breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

beta tubulin mutations are rare in human ovarian carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Enhanced oral bioavailability of paclitaxel by coadministration of the P-glycoprotein inhibitor KR30031.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Lack of beta-tubulin gene mutations in early stage lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Docetaxel for patients with paclitaxel-resistant Müllerian carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2998989

27 October 2018

Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability in human cytochrome P450 paclitaxel metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the ABCB1 gene polymorphisms 2677G>T/A and 3435C>T with clinical outcomes of paclitaxel monotherapy in metastatic breast cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Re: genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic analysis of paclitaxel transport and metabolism genes in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidrug resistance protein 2 is an important determinant of paclitaxel pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of CYP2C8, CYP3A4, CYP3A5, and ABCB1 polymorphisms with the pharmacokinetics of paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl2 is the guardian of microtubule integrity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151855

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/FPC.0B013E3283335277

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34390370&oldid=1549465906"