(Q34400252)

1 August 2017

1 reference

title

Paradox of Bcl-2 (and p53): why may apoptosis-regulating proteins be irrelevant to cell death? (English)

1 reference

1 August 2017

1

Blagosklonny MV

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PubMed ID

11598961

1 August 2017

language of work or name

English

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publication date

1 October 2001

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1 August 2017

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1 August 2017

23

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1 August 2017

947-953

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1 August 2017

10

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Mitochondria and apoptosis

1 August 2017

1 reference

Dysregulation of apoptosis in cancer

21 January 2018

1 reference

Life-or-death decisions by the Bcl-2 protein family.

21 January 2018

1 reference

bcl-2 protein in non-small-cell lung carcinoma

21 January 2018

1 reference

Prognostic significance of Bcl-2 expression and p53 nuclear accumulation in colorectal adenocarcinoma

21 January 2018

1 reference

Bcl-2 protein expression: association with p53 and prognosis in colorectal cancer

21 January 2018

1 reference

Loss of bcl-2 expression in ductal carcinoma in situ of the breast relates to poor histological differentiation and to expression of p53 and c-erbB-2 proteins.

21 January 2018

1 reference

Apoptosis and cancer drug targeting

21 January 2018

1 reference

21 January 2018

1 reference

Clinical implications of p53 mutations

21 January 2018

1 reference

Genetic analysis of chemoresistance in primary murine lymphomas.

21 January 2018

1 reference

The most unkindest cut of all: on the multiple roles of mammalian caspases

21 January 2018

1 reference

Cell death beyond apoptosis

21 January 2018

1 reference

Constitutive expression of the machinery for programmed cell death

21 January 2018

1 reference

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

21 January 2018

1 reference

Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

21 January 2018

1 reference

21 January 2018

More than one way to go.

1 reference

Apoptosis without caspases: an inefficient molecular guillotine?

21 January 2018

1 reference

Nuclear changes in apoptosis.

21 January 2018

1 reference

Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition

21 January 2018

1 reference

Kinases: positive and negative regulators of apoptosis.

21 January 2018

1 reference

Akt regulates cell survival and apoptosis at a postmitochondrial level

21 January 2018

1 reference

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

21 January 2018

1 reference

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

1 reference

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

21 January 2018

1 reference

Elevated expression of Bcl-2 and Bcl-x by intestinal intraepithelial lymphocytes: resistance to apoptosis by glucocorticoids and irradiation

21 January 2018

1 reference

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

21 January 2018

1 reference

Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

21 January 2018

1 reference

Germ cell suicide: new insights into apoptosis during spermatogenesis

21 January 2018

1 reference

Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

21 January 2018

1 reference

Unwinding the loop of Bcl-2 phosphorylation

21 January 2018

1 reference

21 January 2018

1 reference

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

21 January 2018

1 reference

Different impact of p53 and p21 on the radiation response of mouse tissues

21 January 2018

1 reference

p53 alterations in human leukemia-lymphoma cell lines: in vitroartifact or prerequisite for cell immortalization?

21 January 2018

1 reference

21 January 2018

Surfing the p53 network

1 reference

Paclitaxel selects for mutant or pseudo-null p53 in drug resistance associated with tubulin mutations in human cancer.

21 January 2018

1 reference

Sensitivity to Fas-mediated apoptosis in pediatric acute lymphoblastic leukemia is associated with a mutant p53 phenotype and absence of Bcl-2 expression.

21 January 2018

1 reference

In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug.

21 January 2018

1 reference

Apoptosis in cancer: cause and cure

21 January 2018

1 reference

Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase path

21 January 2018

1 reference

Apoptosis suppressing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis

21 January 2018

1 reference

c-myc, p53 and bcl-2, apoptosis-related genes in infiltrating breast carcinomas: evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patients

21 January 2018

1 reference

Differential effects of BCL-2 on survival and proliferation of human B-lymphoma cells following gamma-irradiation

21 January 2018

1 reference

Heat shock protein 70 inhibits apoptosis downstream of cytochrome c release and upstream of caspase-3 activation

21 January 2018

1 reference

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

21 January 2018

1 reference

Bcl-2 accelerates multistep prostate carcinogenesis in vivo

21 January 2018

1 reference

p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIES.1135

1 reference

1 August 2017

1 reference

PubMed ID

11598961