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Kinases: positive and negative regulators of apoptosis.
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Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
review article
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Europe PubMed Central
title
Kinases: positive and negative regulators of apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
main subject
apoptotic process
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inferred from title
author
Richard A. Franklin
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
James A. McCubrey
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
Franklin RA
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11187889
retrieved
31 July 2017
McCubrey JA
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
11187889
retrieved
31 July 2017
publication date
1 December 2000
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Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
2019-2034
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
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Macromolecular substrates for the ICE-like proteases during apoptosis
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Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity
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Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs
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Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism
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p38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide
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Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes
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Diverse Mitogenic Agents Induce the Phosphorylation of Two Related 42,000-Dalton Proteins on Tyrosine in Quiescent Chick Cells
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Major substrate for growth factor-activated protein-tyrosine kinases is a low-abundance protein
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Protein serine/threonine kinases of the MAPK cascade
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MAP kinases ERK1 and ERK2: pleiotropic enzymes in a ubiquitous signaling network
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How MAP kinases are regulated
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7 January 2021
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Parallel signal processing among mammalian MAPKs
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MAPKs: new JNK expands the group
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The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
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Purification of a murine protein-tyrosine/threonine kinase that phosphorylates and activates the Erk-1 gene product: relationship to the fission yeast byr1 gene product
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Extracellular signals and reversible protein phosphorylation: what to Mek of it all.
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Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)
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Mitogen-activated protein kinases: versatile transducers for cell signaling
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MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity
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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
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The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus
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Activation of the MAP kinase pathway by the protein kinase raf
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7 January 2021
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Mammalian Ras interacts directly with the serine/threonine kinase Raf
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Complex formation between RAS and RAF and other protein kinases
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Ras-dependent growth factor regulation of MEK kinase in PC12 cells
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Epidermal growth factor induces phosphorylation of extracellular signal-regulated kinase 2 via multiple pathways
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Platelet-derived growth factor stimulates protein kinase A through a mitogen-activated protein kinase-dependent pathway in human arterial smooth muscle cells
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Differential activation of mitogen-activated protein kinase and S6 kinase signaling pathways by 12-O-tetradecanoylphorbol-13-acetate (TPA) and insulin. Evidence for involvement of a TPA-stimulated protein-tyrosine kinase
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Microfilament assembly is required for anti-IgM dependent MAPK and p90rsk activation in human B lymphocytes.
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AVP-induced activation of MAP kinase in vascular smooth muscle cells is mediated through protein kinase C
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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions
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7 January 2021
based on heuristic
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Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.
1 reference
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7 January 2021
based on heuristic
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Understanding Ras: 'it ain't over 'til it's over'.
1 reference
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7 January 2021
based on heuristic
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Increasing complexity of Ras signaling.
1 reference
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7 January 2021
based on heuristic
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Increasing complexity of the Ras signaling pathway
1 reference
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7 January 2021
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PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS
1 reference
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Crossref
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7 January 2021
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Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.
1 reference
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Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells
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7 January 2021
based on heuristic
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Alternative effects of RAS and RAF oncogenes on the proliferation and apoptosis of factor-dependent FDC-P1 cells
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Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells.
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Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.
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based on heuristic
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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.
1 reference
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based on heuristic
inferred from DOI database lookup
Bc1-2, Raf-1 and mitochondrial regulation of apoptosis
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7 January 2021
based on heuristic
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Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway
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7 January 2021
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inferred from DOI database lookup
Isoform-specific localization of A-RAF in mitochondria
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 targets the protein kinase Raf-1 to mitochondria
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase
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7 January 2021
based on heuristic
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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
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7 January 2021
based on heuristic
inferred from DOI database lookup
CREB and its associated proteins act as survival factors for human melanoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An osmosensing signal transduction pathway in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The stress-activated protein kinase subfamily of c-Jun kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The stress-activated protein kinases. A novel ERK subfamily responsive to cellular stress and inflammatory cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UV irradiation and heat shock mediate JNK activation via alternate pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras signaling in tumor necrosis factor-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The regulation of anoikis: MEKK-1 activation requires cleavage by caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK activation is not required for Fas-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction through NF-kappa B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Function and activation of NF-kappa B in the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rel/NF-kappa B and I kappa B proteins: an overview
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NF-kappa B and I kappa B proteins: new discoveries and insights
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of TNF-alpha-induced apoptosis by NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TGF beta 1 inhibits NF-kappa B/Rel activity inducing apoptosis of B cells: transcriptional activation of I kappa B alpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis-resistant T cells have a deficiency in NF-kappaB-mediated induction of Fas ligand transcription.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biological effects of c-Mer receptor tyrosine kinase in hematopoietic cells depend on the Grb2 binding site in the receptor and activation of NF-kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a role of NF-kappaB in the survival of hematopoietic cells mediated by interleukin 3 and the oncogenic TEL/platelet-derived growth factor receptor beta fusion protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEK kinase is involved in tumor necrosis factor alpha-induced NF-kappaB activation and degradation of IkappaB-alpha.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling by the cytokine receptor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STATs: signal transducers and activators of transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT signaling in the pathogenesis and treatment of leukemias
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Unraveling distinct intracellular signals that promote survival and proliferation: study of erythropoietin, stem cell factor, and constitutive signaling in leukemic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular signalling: putting JAKs on the kinase MAP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two different IL-13 receptor chains are expressed in normal human skin fibroblasts, and IL-4 and IL-13 mediate signal transduction through a common pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of phosphoinositide 3-kinase lipid products in cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoinositide kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of PI 3-kinase in insulin action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation and function of protein kinase B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of activation of protein kinase B by insulin and IGF-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin 3-dependent survival by the Akt protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and regulation of Raf by Akt (protein kinase B)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of cell death protease caspase-9 by phosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinase regulation in inflammatory response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular signalling in programmed cell death (apoptosis).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microinjected catalytic subunit of cAMP-dependent protein kinase induces apoptosis in myeloid leukemia (IPC-81) cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of inhibition of Raf-1 by protein kinase A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interactions between Ras and Raf: key regulatory proteins in cellular transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the Raf-1 kinase by cyclic AMP agonists causes apoptosis of v-abl-transformed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of nitric oxide synthesis by butanol fraction of the methanol extract of Ulmus davidiana in murine macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclic adenosine monophosphate inhibits ursolic acid-induced apoptosis via activation of protein kinase A in human leukaemic HL-60 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type I cAMP-dependent protein kinase delays apoptosis in human neutrophils at a site upstream of caspase-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca2+-activated mechanisms in cell killing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glucocorticoids activate a suicide process in thymocytes through an elevation of cytosolic Ca2+ concentration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium-activated DNA fragmentation kills immature thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of action of cyclosporin A and FK506
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanism of action of cyclosporin A and FK506.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporin A rescues thymocytes from apoptosis induced by very low concentrations of thapsigargin: effects on mitochondrial function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compounds
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate recognition by Ca2+/Calmodulin-dependent protein kinase kinase. Role of the arg-pro-rich insert domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Components of a calmodulin-dependent protein kinase cascade. Molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin-dependent protein kinase kinase beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ca-calmodulin-dependent protein kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium-induced ERK activation in human T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Ca2+/calmodulin-dependent protein kinase (CaM-kinase) IV by CaM-kinase kinase in Jurkat T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of erythroid differentiation and induction of megakaryocytic differentiation by thrombopoietin are regulated by two different mechanisms in TPO-dependent UT-7/c-mpl and TF-1/c-mpl cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GM‐CSF triggers a rapid, glucose dependent extracellular acidification by TF‐1 cells: Evidence for sodium/proton antiporter and PKC mediated activation of acid production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium-induced p56(Lck) phosphorylation in human T lymphocytes via calmodulin dependent kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Platelet activating factor activates MAPK and increases in intracellular calcium via independent pathways in B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p42erk2 MAPK and p90rsk by IL-2 occurs independently of protein kinase C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of protein kinase C function induces an apoptotic response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pro-B-cell-specific transcription and proapoptotic function of protein kinase Ceta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RETRACTED: A new mechanism of neurodegeneration: a proinflammatory cytokine inhibits receptor signaling by a survival peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new concept in neurodegeneration: TNFalpha is a silencer of survival signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.LEU.2401967
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.LEU.2401967
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
Dimensions Publication ID
1020996775
0 references
PubMed publication ID
11187889
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11187889
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11187889%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
ResearchGate publication ID
12142941
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