(Q34403502)

English

Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1 reference

Europe PubMed Central

Predicting drug disposition via application of BCS: transport/absorption/ elimination interplay and development of a biopharmaceutics drug disposition classification system (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

author name string

Chi-Yuan Wu

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Leslie Z Benet

2

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

publication date

1 January 2005

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

22

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

11-23

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Effect of food on the pharmacokinetics of cyclosporine in healthy subjects following oral and intravenous administration

1 reference

https://api.crossref.org/works/10.1007%2FS11095-004-9004-4

21 January 2018

Chris Lipinski discusses life and chemistry after the Rule of Five.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption classification of oral drugs based on molecular surface properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimized conditions for MDCK permeability and turbidimetric solubility studies using compounds representative of BCS classes I-IV.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transporter-Enzyme Interactions: Implications for Predicting Drug-Drug Interactions from In Vitro Data

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midazolam exhibits characteristics of a highly permeable P-glycoprotein substrate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-fat meals increase the clearance of cyclosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physicochemical profiling (solubility, permeability and charge state).

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Conduct of In Vitro and In Vivo Drug-Drug Interaction Studies: A PhRMA Perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of common excipients on Caco-2 transport of low-permeability drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic microsome studies are insufficient to characterize in vivo hepatic metabolic clearance and metabolic drug-drug interactions: studies of digoxin metabolism in primary rat hepatocytes versus microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design of drugs through a consideration of drug metabolism and pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular properties that influence the oral bioavailability of drug candidates

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: studies using the rat single-pass intestinal perfusion model

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biopharmaceutics classification system (BCS): class III drugs - better candidates for BA/BE waiver?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human jejunal effective permeability and its correlation with preclinical drug absorption models

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biopharmaceutics classification system: the scientific basis for biowaiver extensions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of orally administered drugs on the World Health Organization Model list of Essential Medicines according to the biopharmaceutics classification system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Report on the International Workshop on the Biopharmaceutics Classification System (BCS): scientific and regulatory aspects in practice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compound mixtures in Caco-2 cell permeability screens as a means to increase screening capacity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ex situ inhibition of hepatic uptake and efflux significantly changes metabolism: hepatic enzyme-transporter interplay

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of tacrolimus in isolated perfused rat liver: influence of troleandomycin, cyclosporine, and gg918.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-drug, drug-dietary supplement, and drug-citrus fruit and other food interactions: what have we learned?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

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Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fundamental variables of the biopharmaceutics classification system (BCS): a commentary

1 reference

https://pubmed.ncbi.nlm.nih.gov/15771225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-004-9004-4

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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