(Q40647286)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12751631%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Midazolam exhibits characteristics of a highly permeable P-glycoprotein substrate (English)

1 reference

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3 November 2019

1 reference

2

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3 November 2019

author name string

Sanna Tolle-Sander

1

1 reference

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3 November 2019

Steve Wring

3

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3 November 2019

Joseph W Polli

4

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3 November 2019

James E Polli

5

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3 November 2019

publication date

1 May 2003

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3 November 2019

published in

Pharmaceutical Research

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3 November 2019

volume

20

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3 November 2019

page(s)

757-764

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3 November 2019

issue

5

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Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.

3 November 2019

cites work

1 reference

12 December 2020

Molecular and physical mechanisms of first-pass extraction

1 reference

12 December 2020

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery

1 reference

12 December 2020

Effect of modulators on the ATPase activity and vanadate nucleotide trapping of human P-glycoprotein

1 reference

12 December 2020

Methods to compare dissolution profiles and a rationale for wide dissolution specifications for metoprolol tartrate tablets

1 reference

12 December 2020

Selective inhibition of MDR1 P-glycoprotein-mediated transport by the acridone carboxamide derivative GG918.

1 reference

12 December 2020

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

1 reference

12 December 2020

Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.

1 reference

12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

1 reference

12 December 2020

Rational use of in vitro P-glycoprotein assays in drug discovery

1 reference

12 December 2020

Pharmacology of Dormicum (midazolam) and Anexate (flumazenil).

1 reference

12 December 2020

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

1 reference

12 December 2020

Efficiency of P-glycoprotein-mediated exclusion of rhodamine dyes from multidrug-resistant cells is determined by their passive transmembrane movement rate

1 reference

12 December 2020

First-pass metabolism of midazolam by the human intestine.

1 reference

12 December 2020

Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein

1 reference

12 December 2020

Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

1 reference

12 December 2020

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

1 reference

12 December 2020

Influence of passive permeability on apparent P-glycoprotein kinetics.

1 reference

12 December 2020

In vivo cerebral pharmacokinetics and pharmacodynamics of diazepam and midazolam after short intravenous infusion administration in sheep

1 reference

12 December 2020

In vitro correlates of benzodiazepine cerebrospinal fluid uptake, pharmacodynamic action and peripheral distribution.

1 reference

12 December 2020

Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport

1 reference

12 December 2020

Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918.

1 reference

12 December 2020

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

1 reference

12 December 2020

First-pass metabolism of cyclosporin by the gut

1 reference

12 December 2020

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

1 reference

12 December 2020

The role of passive transbilayer drug movement in multidrug resistance and its modulation

1 reference

12 December 2020

The drug efflux-metabolism alliance: biochemical aspects.

1 reference

12 December 2020

First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers.

1 reference

12 December 2020

Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1023433502647

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12751631%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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