(Q34426172)

2 August 2017

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title

Alpha-synuclein and dopamine metabolism (English)

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2 August 2017

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3

Piu Chan

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2 August 2017

2

Kenji Uéda

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2 August 2017

Shun Yu

1

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2 August 2017

publication date

1 January 2005

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2 August 2017

published in

Molecular Neurobiology

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2 August 2017

volume

31

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2 August 2017

issue

1-3

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2 August 2017

page(s)

243-254

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Review: formation and properties of amyloid-like fibrils derived from alpha-synuclein and related proteins

2 August 2017

cites work

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12 December 2020

Absence of mutations in the coding region of the alpha-synuclein gene in pathologically proven Parkinson's disease

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12 December 2020

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

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12 December 2020

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

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12 December 2020

Nuclear localization of alpha-synuclein and its interaction with histones

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12 December 2020

A close association of torsinA and alpha-synuclein in Lewy bodies: a fluorescence resonance energy transfer study

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12 December 2020

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

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12 December 2020

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

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12 December 2020

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

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12 December 2020

Immunoelectron-microscopic demonstration of NACP/alpha-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies

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12 December 2020

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

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12 December 2020

Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture

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12 December 2020

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

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12 December 2020

Activation of Pyk2/RAFTK induces tyrosine phosphorylation of alpha-synuclein via Src-family kinases

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12 December 2020

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

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12 December 2020

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12 December 2020

Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junction

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12 December 2020

Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal

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12 December 2020

Trypsin disrupts the trafficking of the human dopamine transporter by alpha-synuclein and its A30P mutant

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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12 December 2020

Alpha-synuclein and Parkinson's disease

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12 December 2020

Differential localization of alpha-, beta- and gamma-synucleins in the rat CNS

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12 December 2020

Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

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12 December 2020

Characterization of cytoplasmic alpha-synuclein aggregates. Fibril formation is tightly linked to the inclusion-forming process in cells

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12 December 2020

Inhibition of tyrosine hydroxylase expression in alpha-synuclein-transfected dopaminergic neuronal cells

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12 December 2020

Immunohistochemical comparison of alpha- and beta-synuclein in adult rat central nervous system

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12 December 2020

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

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12 December 2020

Genetics of Parkinson's disease and biochemical studies of implicated gene products

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12 December 2020

alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356.

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12 December 2020

A role for alpha-synuclein in the regulation of dopamine biosynthesis

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12 December 2020

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

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12 December 2020

Are ubiquitination pathways central to Parkinson's disease?

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12 December 2020

Abnormal patterns of microtubule-associated protein-2 (MAP-2) immunolabeling in neuronal nuclei and Lewy bodies in Parkinson's disease substantia nigra brain tissues

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12 December 2020

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

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12 December 2020

α-Synuclein aggregation and neurodegenerative diseases

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12 December 2020

Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia

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12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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12 December 2020

Structural changes in alpha-synuclein affect its chaperone-like activity in vitro

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12 December 2020

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

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12 December 2020

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

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12 December 2020

The flux of free radical attack through mitochondrial DNA is related to aging rate

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12 December 2020

Intricate regulation of tyrosine hydroxylase activity and gene expression

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12 December 2020

Postnatal expression of alpha-synuclein protein in the rodent substantia nigra and striatum

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12 December 2020

Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines

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12 December 2020

Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

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12 December 2020

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12 December 2020

Tubulin seeds alpha-synuclein fibril formation

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12 December 2020

Differential cytotoxicity of human wild type and mutant alpha-synuclein in human neuroblastoma SH-SY5Y cells in the presence of dopamine

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12 December 2020

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

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12 December 2020

A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein

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12 December 2020

Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

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12 December 2020

Impaired dopamine storage resulting from alpha-synuclein mutations may contribute to the pathogenesis of Parkinson's disease

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12 December 2020

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

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12 December 2020

Effect of mutant alpha-synuclein on dopamine homeostasis in a new human mesencephalic cell line

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12 December 2020

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

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12 December 2020

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein

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12 December 2020

Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system

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12 December 2020

Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson's disease

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12 December 2020

alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases

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12 December 2020

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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12 December 2020

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

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12 December 2020

Alpha-synuclein and Parkinson's disease

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12 December 2020

Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra

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12 December 2020

alpha-Synuclein regulation of the dopaminergic transporter: a possible role in the pathogenesis of Parkinson's disease

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12 December 2020

α-Synuclein in Lewy bodies

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12 December 2020

Brain 14-3-3 protein is an activator protein that activates tryptophan 5-monooxygenase and tyrosine 3-monooxygenase in the presence of Ca2+,calmodulin-dependent protein kinase II

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12 December 2020

Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones

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12 December 2020

Physiology and pathophysiology of alpha-synuclein. Cell culture and transgenic animal models based on a Parkinson's disease-associated protein.

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12 December 2020

Regulation of tyrosine hydroxylase by stress-activated protein kinases

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12 December 2020

A Drosophila model of Parkinson's disease

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12 December 2020

alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins

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12 December 2020

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

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12 December 2020

Coupling of dopamine oxidation (monoamine oxidase activity) to glutathione oxidation via the generation of hydrogen peroxide in rat brain homogenates

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12 December 2020

Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid.

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12 December 2020

Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments

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12 December 2020

Synucleins are a novel class of substrates for G protein-coupled receptor kinases

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12 December 2020

Attenuation of dopamine transporter activity by alpha-synuclein

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12 December 2020

What have we learnt from CDNA microarray gene expression studies about the role of iron in MPTP induced neurodegeneration and Parkinson's disease?

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12 December 2020

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

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12 December 2020

Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain.

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12 December 2020

alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells

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12 December 2020

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12 December 2020

Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases

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12 December 2020

Mutations in the lipid-binding domain of α-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity

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12 December 2020

Synucleins in synaptic plasticity and neurodegenerative disorders

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12 December 2020

Recent advances in the genetics and pathogenesis of Parkinson disease

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12 December 2020

Pathogenesis of Parkinson's disease: dopamine, vesicles and alpha-synuclein

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12 December 2020

Identifiers

DOI

10.1385/MN:31:1-3:243

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Dimensions Publication ID

2 August 2017

1014757279

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