(Q34430085)

2 August 2017

1 reference

title

Genetically engineered mice and their use in aging research (English)

1 reference

2 August 2017

1 reference

Andersen JK

1

1 reference

2 August 2017

publication date

1 September 2001

1 reference

2 August 2017

published in

Molecular Biotechnology

1 reference

2 August 2017

volume

19

1 reference

2 August 2017

issue

1

1 reference

2 August 2017

page(s)

45-57

1 reference

https://scigraph.springernature.com/pub.10.1385/mb:19:1:045

2 August 2017

exact match

0 references

cites work

Simple and efficient production of embryonic stem cell-embryo chimeras by coculture

1 reference

12 December 2020

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

1 reference

12 December 2020

Derivation of embryonic stem cell lines

1 reference

12 December 2020

Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

1 reference

12 December 2020

Inducible control of gene expression: prospects for gene therapy

1 reference

12 December 2020

Telomerase and mammalian ageing: a critical appraisal

1 reference

12 December 2020

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

1 reference

12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Apolipoprotein E isoforms in Alzheimer's disease pathology and etiology

1 reference

12 December 2020

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1 reference

12 December 2020

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

12 December 2020

Synergistic induction of promoters containing metal- and glucocorticoid-responsive elements

1 reference

12 December 2020

Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter

1 reference

12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

12 December 2020

A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice.

1 reference

12 December 2020

Macrophage specific overexpression of the human macrophage scavenger receptor in transgenic mice, using a 180-kb yeast artificial chromosome, leads to enhanced foam cell formation of isolated peritoneal macrophages.

1 reference

12 December 2020

Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants

1 reference

12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

12 December 2020

The metabolic consequences of altered glucose transporter expression in transgenic mice

1 reference

12 December 2020

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1 reference

12 December 2020

Unusual behavioral phenotypes of inbred mouse strains.

1 reference

12 December 2020

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

1 reference

12 December 2020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

12 December 2020

Somatic mutations and aging: a re-evaluation

1 reference

12 December 2020

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

1 reference

12 December 2020

Animal models for atherosclerosis, restenosis, and endovascular graft research

1 reference

12 December 2020

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

12 December 2020

Alzheimer disease: mouse models pave the way for therapeutic opportunities

1 reference

12 December 2020

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

1 reference

12 December 2020

In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158 --> Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice

1 reference

12 December 2020

Thymic atrophy in the mouse is a soluble problem of the thymic environment.

1 reference

12 December 2020

Murine chromosomal regions correlated with longevity

1 reference

12 December 2020

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse

1 reference

12 December 2020

Can ends justify the means?: telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells

1 reference

12 December 2020

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

1 reference

12 December 2020

The biological clock that measures the mitotic life-span of mouse embryo fibroblasts continues to function in the presence of simian virus 40 large tumor antigen

1 reference

12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

12 December 2020

Replicative senescence: the human fibroblast comes of age.

1 reference

12 December 2020

Altering the genome by homologous recombination

1 reference

12 December 2020

Application of exogenously regulatable promoter systems to transgenic models for the study of aging

1 reference

12 December 2020

Expression of the human beta-amyloid precursor protein gene from a yeast artificial chromosome in transgenic mice

1 reference

12 December 2020

Expression of GLUT-2 antisense RNA in beta cells of transgenic mice leads to diabetes

1 reference

12 December 2020

Immunosenescence: potential causes and strategies for reversal

1 reference

12 December 2020

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

12 December 2020

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

1 reference

12 December 2020

Enhanced insulin action due to targeted GLUT4 overexpression exclusively in muscle.

1 reference

12 December 2020

Targeted disruption of the MHC class II Aa gene in C57BL/6 mice

1 reference

12 December 2020

1 reference

12 December 2020

Mouse models of human genetic disease: which mouse is more like a man?

1 reference

12 December 2020

Inducible and reversible gene expression with the rtTA system for the study of memory.

1 reference

12 December 2020

Mouse models of angiogenesis, arterial stenosis, atherosclerosis and hemostasis

1 reference

12 December 2020

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

12 December 2020

Antisense transgenics in animals

1 reference

12 December 2020

Altered expression of nerve growth factor in the skin of transgenic mice leads to changes in response to mechanical stimuli.

1 reference

12 December 2020

Animal models of atherosclerosis and interpretation of drug intervention studies.

1 reference

12 December 2020

A modular set of Flp, FRT and lacZ fusion vectors for manipulating genes by site-specific recombination

1 reference

12 December 2020

Transcriptional activation by tetracyclines in mammalian cells

1 reference

12 December 2020

Sustained mammary gland-directed, ponasterone A-inducible expression in transgenic mice.

1 reference

12 December 2020

Expression of human FALS SOD in motorneurons of Drosophila.

1 reference

12 December 2020

Transgenic animals in Alzheimer's disease research.

1 reference

12 December 2020

Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction

1 reference

12 December 2020

Heterologous introns can enhance expression of transgenes in mice

1 reference

12 December 2020

Traits that influence longevity in mice: a second look

1 reference

12 December 2020

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

1 reference

12 December 2020

Viewpoint: are studies in genetically altered mice out of control?

1 reference

12 December 2020

Growth retardation in rats whose growth hormone gene expression was suppressed by antisense RNA transgene

1 reference

12 December 2020

Knockout mice: how to make them and why. The immunological approach

1 reference

12 December 2020

1 reference

12 December 2020

Progress toward valid transgenic mouse models for Alzheimer's disease

1 reference

12 December 2020

What causes the build-up of ubiquitin-containing inclusions in Parkinson's disease?

1 reference

12 December 2020

Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

1 reference

12 December 2020

Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice

1 reference

12 December 2020

Non-injection methods for the production of embryonic stem cell-embryo chimaeras

1 reference

12 December 2020

Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2

1 reference

12 December 2020

Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs

1 reference

12 December 2020

Transgenic animals with inducible, targeted gene expression in brain.

1 reference

12 December 2020

Alzheimer transgenic mouse models come of age.

1 reference

12 December 2020

Improvement of insulin action in diabetic transgenic mice selectively overexpressing GLUT4 in skeletal muscle

1 reference

12 December 2020

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

12 December 2020

1 reference

12 December 2020

Developing mouse models of aging: a consideration of strain differences in age-related behavioral and neural parameters

1 reference

12 December 2020

Flp recombinase promotes site-specific DNA recombination in embryonic stem cells and transgenic mice

1 reference

12 December 2020

Inducible gene targeting in mice using the Cre/lox system

1 reference

12 December 2020

Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice

1 reference

12 December 2020

Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant.

1 reference

12 December 2020

Genome engineering: the new mouse genetics

1 reference

12 December 2020

The new mouse genetics: altering the genome by gene targeting

1 reference

12 December 2020

Telomerase: Dr Jekyll or Mr Hyde?

1 reference

12 December 2020

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

12 December 2020

Advanced transgenic and gene-targeting approaches

1 reference

12 December 2020

Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation

1 reference

12 December 2020

Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.

1 reference

12 December 2020

Transgenic animals with altered high-density lipoprotein composition and functions

1 reference

12 December 2020

Dexamethasone nonsuppression in transgenic mice expressing antisense RNA to the glucocorticoid receptor

1 reference

12 December 2020

The role of APOE polymorphisms in late-onset dementias.

1 reference

12 December 2020

Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes

1 reference

12 December 2020

Molecular basis of osteogenesis imperfecta and related disorders of bone.

1 reference

12 December 2020

Inducible gene targeting in mice

1 reference

12 December 2020

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

12 December 2020

Inducible gene expression in the nervous system of transgenic mice

1 reference

12 December 2020

Germ line transmission of yeast artificial chromosomes in transgenic mice.

1 reference

12 December 2020

Genetics of Parkinson's disease

1 reference

12 December 2020

The p66shc adaptor protein controls oxidative stress response and life span in mammals

1 reference

12 December 2020

Control of memory formation through regulated expression of a CaMKII transgene

1 reference

12 December 2020

Identifiers

DOI

10.1385/MB:19:1:045

1 reference

Dimensions Publication ID

2 August 2017

1001557135

0 references

1 reference