(Q34440657)

2 August 2017

1 reference

title

Interleukin-6 and new strategies for the treatment of cancer, hyperproliferative diseases and paraneoplastic syndromes (English)

1 reference

2 August 2017

Beverly E Barton

1

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

Expert Opinion on Therapeutic Targets

2 August 2017

published in

1 reference

2 August 2017

volume

9

1 reference

2 August 2017

issue

4

1 reference

2 August 2017

page(s)

737-752

1 reference

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6.

2 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Differentiation factor/leukemia inhibitory factor protection against lethal endotoxemia in mice: synergistic effect with interleukin 1 and tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Sequence and structural organization of the human gene encoding ciliary neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IL-6: insights into novel biological activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Molecular cloning and expression of an IL-6 signal transducer, gp130

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Kaposi's sarcoma-associated herpesvirus-encoded viral interleukin-6 is secreted and modified differently than human interleukin-6: evidence for a unique autocrine signaling mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

STAT3 is required for the gp130-mediated full activation of the c-myc gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Protein inhibitor of activated STAT3 regulates androgen receptor signaling in prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

SOCS3 regulates the plasticity of gp130 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Activation of STAT3 by the Hepatitis C Virus Core Protein Leads to Cellular Transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IL-6 induces expression of the Fli-1 proto-oncogene via STAT3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Regulation of growth-related genes by interleukin-6 in murine myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Cloning and characterization of novel CIS family genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin-6-deficient mice develop mature-onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin 6 is essential for in vivo development of B lineage neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IL-6 transgenic mouse model for extraosseous plasmacytoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Progenitor cell hyperplasia with rare development of myeloid leukemia in interleukin 11 bone marrow chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

KSHV-encoded viral IL-6 activates multiple human IL-6 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin-6 functions as an autocrine growth factor in human bladder carcinoma cell lines in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Anti-interleukin-6 monoclonal antibody induces regression of human prostate cancer xenografts in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway .

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IL-6 signaling by STAT3 participates in the change from hyperplasia to neoplasia in NRP-152 and NRP-154 rat prostatic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Expression and function of androgen receptor coactivators in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Combinatorial screenings in patients: the interleukin-11 receptor alpha as a candidate target in the progression of human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IL-6 as an intracrine growth factor for renal carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Inhibition of gp130 signaling in breast cancer blocks constitutive activation of Stat3 and inhibits in vivo malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Specific protection against breast cancers by cyclin D1 ablation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

IgG1 plasmacytosis in interleukin 6 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Physiological effects of CNTF-induced wasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

gp130 Cytokine family and bone cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Antisense DNAs as multisite genomic modulators identified by DNA microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Interleukin-6 antisense oligonucleotides inhibit the growth of human myeloma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

KSHV- and EBV-associated germinotropic lymphoproliferative disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Anti-human interleukin-6 receptor antibody inhibits human myeloma growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Inhibition of IL-6 for the treatment of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

The IL-6 receptor antagonist SANT-7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Biological activity of a novel nonpeptide antagonist to the interleukin-6 receptor 20S,21-epoxy-resibufogenin-3-formate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Inhibitory effects of bufadienolides on interleukin-6 in MH-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Development of an IL-6 antagonist peptide that induces apoptosis in 7TD1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

A novel hIL-6 antagonist peptide from computer-aided design contributes to suppression of apoptosis in M1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Induction of interleukin-6 (IL-6) autoantibodies through vaccination with an engineered IL-6 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

Induction of Plasma-Cell Neoplasms in Strain BALB/c Mice with Mineral Oil and Mineral Oil Adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.4.737

21 January 2018

Identifiers

DOI

10.1517/14728222.9.4.737

1 reference

2 August 2017

1 reference