(Q34441113)

2 August 2017

title

Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice (English)

1 reference

amyotrophic lateral sclerosis

2 August 2017

main subject

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1 reference

0 references

Frances J Northington

series ordinal

2

object named as

Frances J Northington

1 reference

2 August 2017

Kevin Chen

1

1 reference

2 August 2017

Lee J Martin

series ordinal

3

1 reference

2 August 2017

publication date

4 November 2009

1 reference

Brain Structure and Function

2 August 2017

published in

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2 August 2017

volume

214

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2 August 2017

issue

2-3

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2 August 2017

page(s)

219-234

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The mitochondrial permeability transition pore: a molecular target for amyotrophic lateral sclerosis therapy

2 August 2017

cites work

1 reference

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The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice

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6 July 2018

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6 July 2018

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6 July 2018

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Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.

6 July 2018

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6 July 2018

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Nitration of the striatal Na,K-ATPase alpha3 isoform occurs in normal brain development but is not increased during hypoxia-ischemia in newborn piglets

6 July 2018

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Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells

6 July 2018

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From molecules to mammals: what's NOS got to do with it?

6 July 2018

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Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

6 July 2018

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Characterization and function of mitochondrial nitric-oxide synthase

6 July 2018

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Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

6 July 2018

1 reference

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Superoxide dismutase and the death of motoneurons in ALS.

6 July 2018

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Amyotrophic lateral sclerosis

6 July 2018

1 reference

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Expression and function of inducible nitric oxide synthase in neurons

6 July 2018

1 reference

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Kalirin inhibition of inducible nitric-oxide synthase

6 July 2018

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Nitric oxide and macrophage function

6 July 2018

1 reference

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1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and in vivo

6 July 2018

1 reference

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A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

6 July 2018

1 reference

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

6 July 2018

1 reference

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

6 July 2018

1 reference

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Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

6 July 2018

1 reference

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Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis

6 July 2018

1 reference

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Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity

6 July 2018

1 reference

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Intermediate filaments of Schwann cells

6 July 2018

1 reference

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Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

6 July 2018

1 reference

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Expression and possible function of nerve growth factor receptors on Schwann cells

6 July 2018

1 reference

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Brain microglia constitutively express beta-2 integrins.

6 July 2018

1 reference

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Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line

6 July 2018

1 reference

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Inducible nitric oxide synthase (iNOS) and nitrotyrosine immunoreactivity in the spinal cords of transgenic mice with a G93A mutant SOD1 gene

6 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00429-009-0226-4

Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00429-009-0226-4

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Ultrastructural study of mitochondria in the spinal cord of transgenic mice with a G93A mutant SOD1 gene

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Reduced p75NTRexpression delays disease onset only in female mice of a transgenic model of familial amyotrophic lateral sclerosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3010349

Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

27 October 2018

1 reference

12 December 2020

Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

12 December 2020

Administration of nitric oxide synthase inhibitors does not alter disease course of amyotrophic lateral sclerosis SOD1 mutant transgenic mice

1 reference

12 December 2020

Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis

1 reference

12 December 2020

Neuronal nitric oxide synthase immunoreactivity in the spinal cord in amyotrophic lateral sclerosis

1 reference

12 December 2020

Expression of nitric oxide synthase isoforms in spinal cord in amyotrophic lateral sclerosis

1 reference

12 December 2020

Survival in a transgenic model of FALS is independent of iNOS expression

1 reference

12 December 2020

Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent

1 reference

12 December 2020

Neuronal nitric oxide synthase (nNOS) immunoreactivity in the spinal cord of transgenic mice with G93A mutant SOD1 gene

1 reference

12 December 2020

Expression of the low affinity neurotrophin receptor p75 in spinal motoneurons in a transgenic mouse model for amyotrophic lateral sclerosis

1 reference

12 December 2020

A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

1 reference

12 December 2020

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

1 reference

12 December 2020

iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis

1 reference

12 December 2020

Intracellular localization and isoform expression of the voltage-dependent anion channel (VDAC) in normal and dystrophic skeletal muscle

1 reference

12 December 2020

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

12 December 2020

Nerve growth factor receptor immunostaining in the spinal cord and peripheral nerves in amyotrophic lateral sclerosis

1 reference

12 December 2020

ALS, SOD and peroxynitrite

1 reference

12 December 2020

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

12 December 2020

Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis

1 reference

12 December 2020

10.1007/S00429-009-0226-4

Identifiers

DOI

1 reference

2 August 2017

1 reference

2 August 2017

1 reference