(Q53588721)

English

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

scientific article published in January 2007

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scholarly article

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death. (English)

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

amyotrophic lateral sclerosis

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1 reference

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inferred from title

William C. Golden

7

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

author name string

Lee J Martin

1

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Zhiping Liu

2

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Kevin Chen

3

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Ann C Price

4

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Yan Pan

5

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Jason A Swaby

6

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

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publication date

1 January 2007

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

The Journal of Comparative Neurology

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

500

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

20-46

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

1

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis

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Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis

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Postnatal phenotype and localization of spinal cord V1 derived interneurons

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7 January 2021

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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

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Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

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ALS, SOD and peroxynitrite

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Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry

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Superoxide dismutase and the death of motoneurons in ALS.

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Lessons from models of SOD1-linked familial ALS.

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Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

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ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

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Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

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Unraveling the mechanisms involved in motor neuron degeneration in ALS

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Increased susceptibility of striatal mitochondria to calcium-induced permeability transition

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Comparative evaluation of synaptophysin-based methods for quantification of synapses

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Increased expression of neuronal nitric oxide synthase spliced variants in reactive astrocytes of amyotrophic lateral sclerosis human spinal cord

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Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1

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Direct nitric oxide imaging in cultured hippocampal neurons with diaminoanthraquinone and confocal microscopy

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Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis

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Developmental cell death: morphological diversity and multiple mechanisms

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Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells

1 reference

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

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Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation.

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Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

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Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.

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7 January 2021

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Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis.

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7 January 2021

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

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Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis

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Inhibition of ICE slows ALS in mice

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Cellular and synaptic localization of the neuronal glutamate transporters excitatory amino acid transporter 3 and 4.

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Na,K-ATPase in the nuclear envelope regulates Na+: K+ gradients in hepatocyte nuclei.

1 reference

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Characterization and function of mitochondrial nitric-oxide synthase

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Low-dose ouabain protects against excitotoxic apoptosis and up-regulates nuclear Bcl-2 in vivo

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Nitration of the striatal Na,K-ATPase alpha3 isoform occurs in normal brain development but is not increased during hypoxia-ischemia in newborn piglets

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Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration

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7 January 2021

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Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

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Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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Motor neuronal death in sporadic amyotrophic lateral sclerosis (ALS) is not apoptotic. A comparative study of ALS and chronic aluminium chloride neurotoxicity in New Zealand white rabbits

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XIAP: apoptotic brake and promising therapeutic target.

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Neuronal NADPH diaphorase is a nitric oxide synthase

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Endocytosis and autophagy in dying neurons: an ultrastructural study in chick embryos

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X-Linked inhibitor of apoptosis protein is involved in mutant SOD1-mediated neuronal degeneration

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The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification

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CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations

1 reference

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7 January 2021

based on heuristic

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Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus

1 reference

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7 January 2021

based on heuristic

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

1 reference

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inferred from DOI database lookup

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

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Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis

1 reference

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Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis

1 reference

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inferred from DOI database lookup

A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice

1 reference

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based on heuristic

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Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

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based on heuristic

inferred from DOI database lookup

Absence of p53: no effect in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Functional Role of Caspase-1 and Caspase-3 in an ALS Transgenic Mouse Model

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Copper- and zinc-containing superoxide dismutase can act as a superoxide reductase and a superoxide oxidase

1 reference

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7 January 2021

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Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

1 reference

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Life and death decisions: the role of the IAPs in modulating programmed cell death

1 reference

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7 January 2021

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inferred from DOI database lookup

Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal death in newborn striatum after hypoxia-ischemia is necrosis and evolves with oxidative stress

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Combined retrograde labeling and calcium imaging in spinal cord and brainstem neurons of the lamprey

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Optical imaging of neuronal activity in tissue labeled by retrograde transport of Calcium Green Dextran.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of apoptosis in mice with ALS

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective loss of alpha motoneurons innervating the medial gastrocnemius muscle in a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Time course of neuropathology in the spinal cord of G86R superoxide dismutase transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired retrograde axonal transport of adenovirus-mediated E. coli LacZ gene in the mice carrying mutant SOD1 gene

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Thalamic neuron apoptosis emerges rapidly after cortical damage in immature mice.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide synthase 1 and nitric oxide synthase 3 protein expression is regionally and temporally regulated in fetal brain.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium imaging of rhythmic network activity in the developing spinal cord of the chick embryo.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis in amyotrophic lateral sclerosis: a review of the evidence.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Upregulation of the pro-apoptotic BH3-only peptide harakiri in spinal neurons of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Survival in a transgenic model of FALS is independent of iNOS expression

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Widespread loss of neuronal populations in the spinal ventral horn in sporadic motor neuron disease. A morphometric study.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Administration of nitric oxide synthase inhibitors does not alter disease course of amyotrophic lateral sclerosis SOD1 mutant transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Spatial nitric oxide imaging using 1,2-diaminoanthraquinone to investigate the involvement of nitric oxide in long-term potentiation in rat brain slices

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

The invulnerability of adult neurons: a critical role for p73.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Is motoneuronal cell death in amyotrophic lateral sclerosis apoptosis?

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Diversity in the mechanisms of neuronal cell death.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of synaptophysin-positive boutons on lumbar motor neurons innervating the medial gastrocnemius muscle of the SOD1G93A G1H transgenic mouse model of ALS.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.21160

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CNE.21160

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17099894

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