(Q34458474)

2 August 2017

title

Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration (English)

1 reference

2 August 2017

1 reference

Lucy Liu

1

0 references

Hector Sandoval

Hector Sandoval

3

0 references

Manish Jaiswal

Manish Jaiswal

5

0 references

Elisenda Sanz

Elisenda Sanz

6

0 references

Albert Quintana

Albert Quintana

10

0 references

Brett H Graham

Brett H Graham

9

0 references

Shinya Yamamoto

Shinya Yamamoto

4

0 references

Hugo J. Bellen

Hugo J Bellen

11

0 references

author name string

Ke Zhang

2

1 reference

2 August 2017

Zhihong Li

7

1 reference

2 August 2017

Jessica Hui

8

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 January 2015

1 reference

2 August 2017

1 reference

2 August 2017

volume

160

1 reference

2 August 2017

issue

1-2

1 reference

2 August 2017

page(s)

177-190

1 reference

Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production

2 August 2017

cites work

1 reference

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6 July 2018

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6 July 2018

1 reference

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Cell survival during complete nutrient deprivation depends on lipid droplet-fueled β-oxidation of fatty acids

6 July 2018

1 reference

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Rapid cell death is preceded by amyloid plaque-mediated oxidative stress

6 July 2018

1 reference

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The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit

6 July 2018

1 reference

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Review: activation patterns of microglia and their identification in the human brain.

6 July 2018

1 reference

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Expanding roles for SREBP in metabolism

6 July 2018

1 reference

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D. melanogaster, mitochondria and neurodegeneration: small model organism, big discoveries.

6 July 2018

1 reference

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Lipoproteins in Drosophila melanogaster--assembly, function, and influence on tissue lipid composition

6 July 2018

1 reference

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Mechanism of oxidative stress in neurodegeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Nutrient-dependent requirement for SOD1 in lifespan extension by protein restriction in Drosophila melanogaster

6 July 2018

1 reference

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Fatal breathing dysfunction in a mouse model of Leigh syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Lipid metabolism in cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Lipid peroxidation and neurodegenerative disease.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Adult neurogenesis in the mammalian brain: significant answers and significant questions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

N-acetylcysteine amide (NACA) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Preferential adhesion maintains separation of ommatidia in the Drosophila eye.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Laser action from 2,6,8-position trisubstituted 1,3,5,7-tetramethylpyrromethene-BF(2) complexes: part 1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Lipid droplets in inflammation and cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

The functional organisation of glia in the adult brain of Drosophila and other insects.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Lipid droplets finally get a little R-E-S-P-E-C-T.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Lipid peroxidation: physiological levels and dual biological effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

SREBPs: SREBP function in glia-neuron interactions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Biomarkers in amyotrophic lateral sclerosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

A mitochondrial protein compendium elucidates complex I disease biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Absence of functional peroxisomes from mouse CNS causes dysmyelination and axon degeneration.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Astrocyte activation and reactive gliosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

C11-BODIPY(581/591), an oxidation-sensitive fluorescent lipid peroxidation probe: (micro)spectroscopic characterization and validation of methodology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

The SREBP pathway in Drosophila: regulation by palmitate, not sterols

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

The biogenesis and functions of lipid bodies in animals, plants and microorganisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Nile red: a selective fluorescent stain for intracellular lipid droplets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

A constant and similar assembly defect of mitochondrial respiratory chain complex I allows rapid identification of NDUFS4 mutations in patients with Leigh syndrome.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Severe CMT type 2 with fatal encephalopathy associated with a novel MFN2 splicing mutation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Mutated mitofusin 2 presents with intrafamilial variability and brain mitochondrial dysfunction

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

N-acetylcysteine amide (AD4) attenuates oxidative stress in beta-thalassemia blood cells

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Fatty acid auxotrophy in Drosophila larvae lacking SREBP.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

A new autosomal recessive spastic ataxia associated with frequent white matter changes maps to 2q33-34.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Neurodegenerative diseases and oxidative stress

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Regulation of SREBP processing and membrane lipid production by phospholipids in Drosophila

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Regional difference of lipid distribution in brain of apolipoprotein E deficient mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4377295

Mitochondrial GTPase mitofusin 2 mutation in Charcot-Marie-Tooth neuropathy type 2A

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25594180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mitochondria and neurodegeneration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25594180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2014.12.019

1 reference

2 August 2017

1 reference

2 August 2017

1 reference