(Q34476762)

2 August 2017

1 reference

title

Caspases in Huntington's disease (English)

1 reference

2 August 2017

0 references

R O Sanchez Mejia

1

1 reference

PubMed ID

11765125

2 August 2017

R M Friedlander

series ordinal

2

1 reference

2 August 2017

1 December 2001

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2 August 2017

1 reference

2 August 2017

7

1 reference

2 August 2017

480-489

1 reference

2 August 2017

6

1 reference

Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.

2 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

A polymorphic DNA marker genetically linked to Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Molecular basis of the neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Recent advances on the pathogenesis of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Widespread expression of Huntington's disease gene (IT15) protein product

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F107385840100700604

10.1177/107385840100700604

21 January 2018

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11765125