(Q34511474)

2 August 2017

title

Identification of novel multitargeted PPARα/γ/δ pan agonists by core hopping of rosiglitazone (English)

1 reference

2 August 2017

1 reference

Xue-Jiao Wang

1

1 reference

2 August 2017

Jun Zhang

2

1 reference

2 August 2017

Shu-Qing Wang

3

1 reference

2 August 2017

Wei-Ren Xu

4

1 reference

2 August 2017

Xian-Chao Cheng

5

1 reference

2 August 2017

Run-Ling Wang

6

1 reference

2 August 2017

language of work or name

English

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publication date

7 November 2014

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Drug Design, Development and Therapy

2 August 2017

published in

1 reference

2 August 2017

volume

8

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2 August 2017

page(s)

2255-2262

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Creative Commons Attribution-NonCommercial 3.0 Unported

2 August 2017

copyright license

start time

1 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease

7 July 2018

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In vivo actions of peroxisome proliferator-activated receptors: glycemic control, insulin sensitivity, and insulin secretion

7 July 2018

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Peroxisome proliferator-activated receptor (PPAR)β/δ, a possible nexus of PPARα- and PPARγ-dependent molecular pathways in neurodegenerative diseases: Review and novel hypotheses

7 July 2018

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Peroxisome proliferator-activated receptor targets for the treatment of metabolic diseases

7 July 2018

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Selective peroxisome proliferator-activated receptor α modulators (SPPARMα): the next generation of peroxisome proliferator-activated receptor α-agonists

7 July 2018

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Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization

7 July 2018

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7 July 2018

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Discovery of a novel selective PPARγ ligand with partial agonist binding properties by integrated in silico/in vitro work flow.

7 July 2018

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Identification of PPARgamma partial agonists of natural origin (II): in silico prediction in natural extracts with known antidiabetic activity

7 July 2018

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Identification of PPARgamma partial agonists of natural origin (I): development of a virtual screening procedure and in vitro validation

7 July 2018

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Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach

7 July 2018

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Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding

7 July 2018

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Mode of peroxisome proliferator-activated receptor γ activation by luteolin

7 July 2018

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Novel inhibitor design for hemagglutinin against H1N1 influenza virus by core hopping method

7 July 2018

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Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ

7 July 2018

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An allosteric mechanism inferred from molecular dynamics simulations on phospholamban pentamer in lipid membranes

7 July 2018

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Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures

7 July 2018

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Monokine induced by interferon gamma (IFNgamma) (CXCL9) and IFNgamma inducible T-cell alpha-chemoattractant (CXCL11) involvement in Graves' disease and ophthalmopathy: modulation by peroxisome proliferator-activated receptor-gamma agonists

7 July 2018

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Discovery of novel PPAR ligands by a virtual screening approach based on pharmacophore modeling, 3D shape, and electrostatic similarity screening

7 July 2018

1 reference

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Dedifferentiated thyroid cancer: a therapeutic challenge

7 July 2018

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Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Safety issues and prospects for future generations of PPAR modulators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Integrated Modeling Program, Applied Chemical Theory (IMPACT)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

ZINC--a free database of commercially available compounds for virtual screening

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Life-science applications of the Cambridge Structural Database

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Prediction of intestinal permeability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Structure of the PPARalpha and -gamma ligand binding domain in complex with AZ 242; ligand selectivity and agonist activation in the PPAR family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Structure-based identification of novel PPAR gamma ligands.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Computational studies on the substrate interactions of influenza A virus PB2 subunit

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

On the weak O-H···halogen hydrogen bond: a rotational study of CH3CHClF···H2O

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Docking and molecular dynamics study on the inhibitory activity of novel inhibitors on epidermal growth factor receptor (EGFR).

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Binding mechanism of coronavirus main proteinase with ligands and its implication to drug design against SARS.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Chris Lipinski discusses life and chemistry after the Rule of Five

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4232041

Mode of action and adverse effects of lipid lowering drugs

27 October 2018

1 reference

12 December 2020

Indanylacetic acids as PPAR-delta activator insulin sensitizers

1 reference

12 December 2020

Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds

1 reference

12 December 2020

Docking, synthesis and anti-diabetic activity of novel sulfonylhydrazone derivatives designed as PPAR-gamma agonists

1 reference

12 December 2020

Identification of proteins interacting with human SP110 during the process of viral infections

1 reference

12 December 2020

Identifiers

DOI

10.2147/DDDT.S70383

1 reference

2 August 2017

1 reference

2 August 2017

1 reference