(Q34515762)

2 August 2017

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title

Convergence of mitogenic and DNA damage signaling in the G1 phase of the cell cycle (English)

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2 August 2017

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1

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2 August 2017

Rene Bernards

2

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language of work or name

English

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publication date

1 March 2002

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2 August 2017

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2 August 2017

177

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2 August 2017

2

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2 August 2017

111-118

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Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

1 reference

7 January 2021

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Oncogenes and the strategy of growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

A Restriction Point for Control of Normal Animal Cell Proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Checkpoints: controls that ensure the order of cell cycle events

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Checking out the G(2)/M transition.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Oncogenic kinase signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

The retinoblastoma gene family in differentiation and development.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Specific protection against breast cancers by cyclin D1 ablation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

New functional activities for the p21 family of CDK inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

p21-containing cyclin kinases exist in both active and inactive states

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Distinct roles for cyclin-dependent kinases in cell cycle control

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Cyclins D1 and D2 mediate myc-induced proliferation via sequestration of p27(Kip1) and p21(Cip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

beta-catenin signaling and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

A cell cycle-regulated inhibitor of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

pRB plays an essential role in cell cycle arrest induced by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2801%2900785-6

7 January 2021

10.1016/S0304-3835(01)00785-6

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11825657