(Q34520015)

27018887

2 August 2017

title

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification (English)

1 reference

2 August 2017

0 references

0 references

6

1 reference

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2 June 2020

Luke A Gilbert

7

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2 June 2020

Jan E Carette

12

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2 June 2020

author name string

Richard M Deans

1

1 reference

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2 June 2020

David W Morgens

2

1 reference

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2 June 2020

Ayşe Ökesli

3

1 reference

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2 June 2020

Sirika Pillay

4

1 reference

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2 June 2020

Max A Horlbeck

5

1 reference

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2 June 2020

Amy Li

8

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2 June 2020

Roberto Mateo

9

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2 June 2020

Mark Smith

10

1 reference

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2 June 2020

Jeffrey S Glenn

11

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2 June 2020

Chaitan Khosla

13

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2 June 2020

Michael C Bassik

14

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2 June 2020

language of work or name

1 reference

28 March 2016

1 reference

27018887

2 August 2017

published in

Nature Chemical Biology

1 reference

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2 June 2020

volume

12

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2 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27018887%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

361-366

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https://scigraph.springernature.com/pub.10.1038/nchembio.2050

2 June 2020

exact match

0 references

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A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

7 July 2018

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7 July 2018

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Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis

7 July 2018

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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

7 July 2018

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A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility

7 July 2018

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7 July 2018

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Multiplex genome engineering using CRISPR/Cas systems

7 July 2018

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Identifying mechanism-of-action targets for drugs and probes.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase

7 July 2018

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7 July 2018

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Tetrahydrocarbazole amides with potent activity against human papillomaviruses.

21 January 2018

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Importance of ribonucleotide availability to proliferating T-lymphocytes from healthy humans. Disproportionate expansion of pyrimidine pools and contrasting effects of de novo synthesis inhibitors.

21 January 2018

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Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase. A versatile tool to rate inhibitor effects?

21 January 2018

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Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

27 October 2018

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21 January 2018

Identifiers

DOI

10.1038/NCHEMBIO.2050

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27018887%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27018887%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

27018887

1 reference