(Q34520595)

2 August 2017

Phase 1 study of MLN8054, a selective inhibitor of Aurora A kinase in patients with advanced solid tumors (English)

1 reference

2 August 2017

6

Margaret von Mehren

1 reference

2 August 2017

0 references

1

E Claire Dees

1 reference

2 August 2017

Jeffrey R Infante

2

1 reference

2 August 2017

Roger B Cohen

3

1 reference

2 August 2017

Bert H O'Neil

4

1 reference

2 August 2017

Suzanne Jones

5

1 reference

2 August 2017

Hadi Danaee

7

1 reference

2 August 2017

Yih Lee

8

1 reference

2 August 2017

Jeffrey Ecsedy

9

1 reference

2 August 2017

Mark Manfredi

10

1 reference

2 August 2017

Katherine Galvin

11

1 reference

2 August 2017

Bradley Stringer

12

1 reference

2 August 2017

Hua Liu

13

1 reference

2 August 2017

Omar Eton

14

1 reference

2 August 2017

Howard Fingert

15

1 reference

2 August 2017

Howard Burris

16

1 reference

2 August 2017

7 July 2010

1 reference

Cancer Chemotherapy and Pharmacology

2 August 2017

1 reference

2 August 2017

67

1 reference

2 August 2017

4

1 reference

2 August 2017

945-954

1 reference

https://scigraph.springernature.com/pub.10.1007/s00280-010-1377-y

2 August 2017

0 references

cites work

Expression of Aurora A (but not Aurora B) is predictive of survival in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Aurora kinases as anticancer drug targets

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Overexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

MLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Targeted anti-mitotic therapies: can we improve on tubulin agents?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Biological characteristics in bladder cancer depend on the type of genetic instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Aurora-kinase inhibitors as anticancer agents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

The cellular geography of aurora kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Mitotic kinases as regulators of cell division and its checkpoints

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026871

Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00280-010-1377-Y

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00280-010-1377-Y

Amplification/overexpression of a mitotic kinase gene in human bladder cancer

21 January 2018

1 reference

12 December 2020

Potential roles for preclinical pharmacology in phase I clinical trials

1 reference

12 December 2020

Aurora kinase inhibitors in preclinical and clinical testing

1 reference

12 December 2020

Prognosis and gene expression profiling of 20q13-amplified breast cancers

1 reference

12 December 2020

10.1007/S00280-010-1377-Y

Identifiers

DOI

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference