(Q34531308)

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A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

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scholarly article

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Europe PubMed Central

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21 February 2020

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells (English)

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21 February 2020

Marie-Anne Debily

5

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21 February 2020

author name string

Li Xie

1

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21 February 2020

Claude Gazin

2

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21 February 2020

Sung Mi Park

3

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21 February 2020

Lihua J Zhu

4

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21 February 2020

Ellen L W Kittler

6

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21 February 2020

Maria L Zapp

7

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21 February 2020

David Lapointe

8

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21 February 2020

Stephane Gobeil

9

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21 February 2020

Ching-Man Virbasius

10

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21 February 2020

Michael R Green

11

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21 February 2020

publication date

20 December 2012

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21 February 2020

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21 February 2020

8

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21 February 2020

e1003151

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21 February 2020

12

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21 February 2020

copyright license

Creative Commons Attribution 4.0 International

20 December 2012

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April 2022 Public Data File from Crossref

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0 references

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p53 and p16(INK4A) independent induction of senescence by chromatin-dependent alteration of S-phase progression

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Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1)

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Translating p53 into the clinic.

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Tumor protein 53 mutations and inherited cancer: beyond Li-Fraumeni syndrome.

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Awakening guardian angels: drugging the p53 pathway

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An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

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A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

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Telomerase modulates Wnt signalling by association with target gene chromatin

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Rapid creation and quantitative monitoring of high coverage shRNA libraries

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A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway

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Principles of cancer therapy: oncogene and non-oncogene addiction

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Telomerase: cellular immortalization and neoplastic transformation. Multiple functions of a multifaceted complex.

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A review of contusugene ladenovec (Advexin) p53 therapy.

1 reference

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GammaH2AX and cancer

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Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers

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ATR: an essential regulator of genome integrity

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Oncogene addiction

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TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program

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Reactivation of mutant p53: molecular mechanisms and therapeutic potential

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1 reference

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27 October 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23284306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TERT regulates cell survival independent of telomerase enzymatic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284306

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based on heuristic

inferred from PubMed ID database lookup

p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/23284306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1003151

1 reference

Europe PubMed Central

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21 February 2020

release_dooplqvhrbefdpkxhnl5gzbk4a

1 reference

https://api.fatcat.wiki/v0/release/dooplqvhrbefdpkxhnl5gzbk4a

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

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21 February 2020

1 reference

Europe PubMed Central

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21 February 2020

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