(Q35180856)

7 August 2017

title

Wild-type p53 controls cell motility and invasion by dual regulation of MET expression (English)

1 reference

7 August 2017

Chang-Il Hwang

1

0 references

Carla Boccaccio

object named as

Carla Boccaccio

7

0 references

Paolo M. Comoglio

object named as

Paolo M Comoglio

9

0 references

author name string

Andres Matoso

2

1 reference

7 August 2017

David C Corney

3

1 reference

7 August 2017

Andrea Flesken-Nikitin

4

1 reference

7 August 2017

Stefanie Körner

5

1 reference

7 August 2017

Wei Wang

6

1 reference

7 August 2017

Snorri S Thorgeirsson

8

1 reference

7 August 2017

Heiko Hermeking

10

1 reference

7 August 2017

Alexander Yu Nikitin

11

1 reference

7 August 2017

language of work or name

English

0 references

publication date

9 August 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

1 reference

7 August 2017

volume

108

1 reference

7 August 2017

issue

34

1 reference

7 August 2017

page(s)

14240-14245

1 reference

p53 and its mutants in tumor cell migration and invasion

7 August 2017

cites work

1 reference

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The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

13 July 2018

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Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

13 July 2018

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Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

13 July 2018

1 reference

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Frequent downregulation of miR-34 family in human ovarian cancers

13 July 2018

1 reference

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Mutant p53 drives invasion by promoting integrin recycling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Awakening guardian angels: drugging the p53 pathway

13 July 2018

1 reference

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When mutants gain new powers: news from the mutant p53 field.

13 July 2018

1 reference

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The biology of ovarian cancer: new opportunities for translation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Blinded by the Light: The Growing Complexity of p53

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

MicroRNAs impair MET-mediated invasive growth

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Drug development of MET inhibitors: targeting oncogene addiction and expedience

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Sp1: emerging roles--beyond constitutive activation of TATA-less housekeeping genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

p53 enters the microRNA world

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Loss of p53 promotes RhoA-ROCK-dependent cell migration and invasion in 3D matrices

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

A microRNA component of the p53 tumour suppressor network

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Molecular mechanisms of transactivation and doxorubicin-mediated repression of survivin gene in cancer cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

The Met pathway: master switch and drug target in cancer progression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Why did p53 gene therapy fail in ovarian cancer?

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Sp1 and Sp3 transcription factors synergistically regulate HGF receptor gene expression in kidney

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

CD44 is required for two consecutive steps in HGF/c-Met signaling.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Sp1 plays a critical role in the transcriptional activation of the human cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by the p53 tumor suppressor protein

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Changes in p53 expression in mouse fibroblasts can modify motility and extracellular matrix organization.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Distant metastases in ovarian cancer: association with p53 mutations.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Regulation of the c-met proto-oncogene promoter by p53.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

p53 represses Sp1 DNA binding and HIV-LTR directed transcription

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Ets up-regulates MET transcription

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

The p53 tumor suppressor gene frequently is altered in gynecologic cancers

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

WAF1, a potential mediator of p53 tumor suppression

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Mutation and expression of the TP53 gene in early stage epithelial ovarian carcinoma

13 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017536108

Spectrum of p53 tumor suppressor gene mutations and breast cancer survival

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017536108

Intraepithelial carcinoma of the fimbria and pelvic serous carcinoma: Evidence for a causal relationship.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1017536108

p53-Mediated down-regulation of the human DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) via interaction with Sp1 transcription factor

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161601

p53 null mutations undetected by immunohistochemical staining predict a poor outcome with early-stage non-small cell lung carcinomas

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21831840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21831840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21831840

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1017536108

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference