(Q34539063)

English

Analysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Analysis of the quantitative balance between insulin-like growth factor (IGF)-1 ligand, receptor, and binding protein levels to predict cell sensitivity and therapeutic efficacy (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2

object named as

Pamela K Kreeger

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Dan Tian

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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based on heuristic

inferred from title

publication date

13 August 2014

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Europe PubMed Central

PubMed publication ID

2 August 2017

BMC Systems Biology

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Europe PubMed Central

PubMed publication ID

2 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

98

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

13 August 2014

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April 2022 Public Data File from Crossref

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0 references

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Signalling by insulin and IGF receptors: supporting acts and new players

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Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling.

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Tumor-associated retinal astrocytes promote retinoblastoma cell proliferation through production of IGFBP-5

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Insulin and insulin-like growth factor-1 receptors act as ligand-specific amplitude modulators of a common pathway regulating gene transcription

1 reference

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Mechanisms of antibody-mediated insulin-like growth factor I receptor (IGF-IR) down-regulation in MCF-7 breast cancer cells.

1 reference

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Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

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Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

1 reference

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Safety, pharmacokinetics, and pharmacodynamics of the insulin-like growth factor type 1 receptor inhibitor figitumumab (CP-751,871) in combination with paclitaxel and carboplatin

1 reference

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7 July 2018

Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer

1 reference

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7 July 2018

AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics

1 reference

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7 July 2018

Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data

1 reference

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7 July 2018

Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin-like growth factor binding protein-3 (IGFBP-3) acts as an invasion-metastasis suppressor in ovarian endometrioid carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin-like growth factor-binding protein-5 enters vesicular structures but not the nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin-like growth factor-binding protein-5 (IGFBP-5): a critical member of the IGF axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The therapeutic potential of agents targeting the type I insulin-like growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin and IGF-1 receptor trafficking and signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Synthesis and characterization of biotinylated forms of insulin-like growth factor-1: topographical evaluation of the IGF-1/IGFBP-2 AND IGFBP-3 interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The insulin like growth factor-1 receptor (IGF-1R) as a drug target: novel approaches to cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The IGF‐1 receptor in cancer biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The insulin-like growth factor system and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Mannose 6-phosphate receptors: new twists in the tale

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Cellular actions of the insulin-like growth factor binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Role of the insulin-like growth factor family in cancer development and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The insulin-like growth factor-binding protein (IGFBP) superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin-like growth factor I is essential for terminal end bud formation and ductal morphogenesis during mammary development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Targeted gene mutations define the roles of insulin and IGF-I receptors in mouse embryonic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Control of EGF receptor signaling by clathrin-mediated endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Receptor-mediated effects on ligand availability influence relative mitogenic potencies of epidermal growth factor and transforming growth factor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Role of insulin-like growth factors in embryonic and postnatal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

IGF-I is required for normal embryonic growth in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Inactivation of the IGF-I gene in mice results in perinatal lethality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Functional properties of antibody insulin-like growth factor fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Insulin-like growth factors and their binding proteins: biological actions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

The insulin-like growth factor I receptor protects tumor cells from apoptosis in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Evidence that human bone cells in culture produce insulin-like growth factor-binding protein-4 and -5 proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Receptor-mediated endocytosis and lysosomal processing of insulin-like growth factor I by mitogenically responsive cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Differential signalling potential of insulin- and IGF-1-receptor cytoplasmic domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Chromaffin cells express two types of insulin-like growth factor receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

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1 reference

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7 July 2018

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1 reference

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7 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Expression of a type I insulin-like growth factor receptor with low affinity for insulin-like growth factor II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

7 July 2018

Antitumor activity of GSK1904529A, a small-molecule inhibitor of the insulin-like growth factor-I receptor tyrosine kinase

1 reference

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21 January 2018

Insulin-like growth factor type-I receptor internalization and recycling mediate the sustained phosphorylation of Akt.

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Serum IGF-I, its major binding protein (IGFBP-3) and epithelial ovarian cancer risk: the European Prospective Investigation into Cancer and Nutrition (EPIC)

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Circulating levels of insulin-like growth factor-I and risk of ovarian cancer

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

High insulin-like growth factor-2 (IGF-2) gene expression is an independent predictor of poor survival for patients with advanced stage serous epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Expression of insulin-like growth factor I receptor and survival in patients with clear cell renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Local expression of insulin-like growth factor-I, insulin-like growth factor-I receptor, and estrogen receptor alpha in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2.

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

27 October 2018

Insulin-like growth factor I regulates renal development in rodents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4236724

27 October 2018

IGF-1R is overexpressed in poor-prognostic subtypes of multiple myeloma

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

IGFBP-3 in epithelial ovarian carcinoma and its association with clinico-pathological features and patient survival

1 reference

https://api.crossref.org/works/10.1186%2FS12918-014-0098-Y

21 January 2018

Insulin-like growth factor (IGF)-I, IGF-II and IGF type I receptor (IGFR-I) expression in prostatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seminars in medicine of the Beth Israel Deaconess Medical Center. Insulin-like growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3'-kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I in epithelial ovarian cancer and its role in disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential secretory polarity of IGFBP-6 vs. IGFBP-2 and IGFBP-4 in human intestinal epithelial cells: is it a way of modulating IGF-II bioavailability towards the IGF-responsive basolateral surface?

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https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Observations on the social behaviour of cells in tissue culture. II. Monolayering of fibroblasts

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https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between epidermal growth factor receptor occupancy and mitogenic response. Quantitative analysis using a steady state model system

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered ligand binding by insulin-like growth factor II/mannose 6-phosphate receptors bearing missense mutations in human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25115504

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based on heuristic

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Presence and characterization of insulin-like growth factor 1 receptors in human benign breast disease

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based on heuristic

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Identifiers

10.1186/S12918-014-0098-Y

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

DBLP publication ID

journals/bmcsb/TianK14

1 reference

DBLP Dataset 2021-01-02

28 January 2021

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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