(Q34548866)

3 August 2017

1 reference

title

Rules for modeling signal-transduction systems (English)

1 reference

3 August 2017

2

James R Faeder

1 reference

3 August 2017

Michael Hucka

5

0 references

author name string

William S Hlavacek

1

1 reference

3 August 2017

Michael L Blinov

3

1 reference

3 August 2017

Richard G Posner

4

1 reference

3 August 2017

Walter Fontana

6

1 reference

3 August 2017

18 July 2006

1 reference

Science's STKE : signal transduction knowledge environment

3 August 2017

1 reference

3 August 2017

2006

1 reference

3 August 2017

344

1 reference

3 August 2017

re6

1 reference

3 August 2017

Targeted cancer therapy

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Systems biology in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Systems modeling: a pathway to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Signaling--2000 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Computational approaches for modeling regulatory cellular networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Reconstruction of cellular signalling networks and analysis of their properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Computational modeling of the EGF-receptor system: a paradigm for systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Mathematical and computational models of immune-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Current challenges in quantitative modeling of epidermal growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

The complexity of complexes in signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Examining multiprotein signaling complexes from all angles

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Movies, measurement, and modeling: the three Ms of mechanistic immunology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A quantitative protein interaction network for the ErbB receptors using protein microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Protein posttranslational modifications: the chemistry of proteome diversifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Assembly of Cell Regulatory Systems Through Protein Interaction Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

The modular logic of signaling proteins: building allosteric switches from simple binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

SMART 4.0: towards genomic data integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Evolution of the protein repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

PROTEIN FAMILIES AND THEIR EVOLUTION—A STRUCTURAL PERSPECTIVE

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Multisite protein modification and intramolecular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Modelling cellular behaviour

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Genomics. Molecular prodigality

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Molecular interaction map of the mammalian cell cycle control and DNA repair systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Epidermal growth factor receptor: mechanisms of activation and signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

The death domain superfamily: a tale of two interfaces?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Fire and death: the pyrin domain joins the death-domain superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Three-dimensional structure of a complex between the death domains of Pelle and Tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Investigation of early events in Fc epsilon RI-mediated signaling using a detailed mathematical model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Combinatorial complexity and dynamical restriction of network flows in signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Computer-based analysis of the binding steps in protein complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

The immunological synapse balances T cell receptor signaling and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Quantitative cell biology with the Virtual Cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

An integrated model of epidermal growth factor receptor trafficking and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Self-organization of polarized cell signaling via autocrine circuits: computational model analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A network model of early events in epidermal growth factor receptor signaling that accounts for combinatorial complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Automatic generation of cellular reaction networks with Moleculizer 1.0.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

'On-the-fly' or 'generate-first' modeling?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Collaborative signaling by bacterial chemoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Signal transduction in bacterial chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Computer simulation of the phosphorylation cascade controlling bacterial chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Computer analysis of the binding reactions leading to a transmembrane receptor-linked multiprotein complex involved in bacterial chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Predicting temporal fluctuations in an intracellular signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Polymerization of the SAM domain of MAPKKK Ste11 from the budding yeast: implications for efficient signaling through the MAPK cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Cellerator: extending a computer algebra system to include biochemical arrows for signal transduction simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

STOCHSIM: modelling of stochastic biomolecular processes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A spatially extended stochastic model of the bacterial chemotaxis signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Kinetic proofreading in T-cell receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Space in systems biology of signaling pathways--towards intracellular molecular crowding in silico

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A general method for numerically simulating the stochastic time evolution of coupled chemical reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Exact stochastic simulation of coupled chemical reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

An algebra of dimerization and its implications for G-protein coupled receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

On the cross-regulation of protein tyrosine phosphatases and receptor tyrosine kinases in intracellular signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

An enzyme mechanism language for the mathematical modeling of metabolic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Reduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Anticancer effects of ZD6474, a VEGF receptor tyrosine kinase inhibitor, in gefitinib ("Iressa")-sensitive and resistant xenograft models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A graph-based toy model of chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Autocatalytic replication of polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Validation of qualitative models of genetic regulatory networks by model checking: analysis of the nutritional stress response in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Approximate accelerated stochastic simulation of chemically reacting systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

From play to laws: language in biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Application of a stochastic name-passing calculus to representation and simulation of molecular processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Modelling the dynamics of biosystems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Concurrency in leukocyte vascular recognition: developing the tools for a predictive computer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Minimum information requested in the annotation of biochemical models (MIRIAM)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

BioModels Database: a free, centralized database of curated, published, quantitative kinetic models of biochemical and cellular systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Systems biology markup language: Level 2 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Evolving a lingua franca and associated software infrastructure for computational systems biology: the Systems Biology Markup Language (SBML) project

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Literature mining for the biologist: from information retrieval to biological discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Inferring protein domain interactions from databases of interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Molecular interaction maps of bioregulatory networks: a general rubric for systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

CADLIVE for constructing a large-scale biochemical network based on a simulation-directed notation and its application to yeast cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Artificial chemistries--a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Local rule-based theory of virus shell assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Simulation study of the contribution of oligomer/oligomer binding to capsid assembly kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

Synthetic modular systems--reverse engineering of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.3442006RE6

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

21 January 2018

1 reference

7 July 2022

https://opencitations.net/index/coci/api/v1/citations/10.1093/BIOINFORMATICS/BTG015

Identifiers

DOI

10.1126/STKE.3442006RE6

1 reference

3 August 2017

1 reference