(Q34551101)

3 August 2017

1 reference

title

Cyclooxygenases and 5-lipoxygenase in Alzheimer's disease (English)

1 reference

3 August 2017

0 references

3

Svetlana Dzitoyeva

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

18 June 2024

author name string

Hari Manev

series ordinal

1

1 reference

3 August 2017

Hu Chen

series ordinal

2

1 reference

3 August 2017

Radmila Manev

series ordinal

4

1 reference

3 August 2017

language of work or name

1 reference

5 August 2010

1 reference

full work available at URL

3 August 2017

https://europepmc.org/articles/pmc3033490?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20691748/?tool=EBI

18 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20691748/pdf/?tool=EBI

18 June 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

https://europepmc.org/articles/PMC3033490

18 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

https://europepmc.org/articles/PMC3033490?pdf=render

18 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

https://doi.org/10.1016/j.pnpbp.2010.07.032

18 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691748

https://api.elsevier.com/content/article/PII:S0278584610002988?httpAccept=text/xml

18 June 2024

1 reference

10.1016/J.PNPBP.2010.07.032

Crossref

DOI

https://api.crossref.org/works/10.1016/J.PNPBP.2010.07.032

https://api.elsevier.com/content/article/PII:S0278584610002988?httpAccept=text/plain

18 June 2024

1 reference

10.1016/J.PNPBP.2010.07.032

Crossref

DOI

https://api.crossref.org/works/10.1016/J.PNPBP.2010.07.032

Progress in Neuro-Psychopharmacology & Biological Psychiatry

18 June 2024

published in

1 reference

3 August 2017

volume

35

1 reference

3 August 2017

issue

2

1 reference

3 August 2017

page(s)

315-319

1 reference

Zileuton reduces inflammatory reaction and brain damage following permanent cerebral ischemia in rats

3 August 2017

cites work

1 reference

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Very long-chain fatty acid accumulation causes lipotoxic response via 5-lipoxygenase in cerebral adrenoleukodystrophy

7 July 2018

1 reference

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Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid

7 July 2018

1 reference

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Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.

7 July 2018

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5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice

7 July 2018

1 reference

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The 5-lipoxygenase as a common pathway for pathological brain and vascular aging

7 July 2018

1 reference

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Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain

7 July 2018

1 reference

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5-Lipoxygenase in the Prefrontal Cortex of Suicide Victims

7 July 2018

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Docosahexaenoic acid neurolipidomics

7 July 2018

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Role of DNA methylation and methyl-DNA binding proteins in the repression of 5-lipoxygenase promoter activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Vascular biology of eicosanoids and atherogenesis

7 July 2018

1 reference

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An update on the efficacy of non-steroidal anti-inflammatory drugs in Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor.

7 July 2018

1 reference

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The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

7 July 2018

1 reference

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Brain arachidonic and docosahexaenoic acid cascades are selectively altered by drugs, diet and disease

7 July 2018

1 reference

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Increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

The neuroprotective effect of prostaglandin E2 EP1 receptor inhibition has a wide therapeutic window, is sustained in time and is not sexually dimorphic.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Cyclooxygenase-2 in synaptic signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Possible mechanisms of action of NSAIDs and related compounds that modulate gamma-secretase cleavage.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

7 July 2018

1 reference

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DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Gene expression of cyclooxygenase-1 and Ca(2+)-independent phospholipase A(2) is altered in rat hippocampus during normal aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Coxibs and Alzheimer's disease: should they stay or should they go?

7 July 2018

1 reference

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Microglial EP2 as a new target to increase amyloid beta phagocytosis and decrease amyloid beta-induced damage to neurons

7 July 2018

1 reference

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Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases

7 July 2018

1 reference

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Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism

7 July 2018

1 reference

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Aging-associated up-regulation of neuronal 5-lipoxygenase expression: putative role in neuronal vulnerability

7 July 2018

1 reference

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COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortex

7 July 2018

1 reference

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Nonsteroidal antiinflammatory drug use in Alzheimer's disease.

7 July 2018

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Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions

7 July 2018

1 reference

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Anti-inflammatory drugs and Alzheimer disease.

7 July 2018

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Leukotrienes in brain: natural occurrence and induced changes

7 July 2018

1 reference

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Early-stage inflammation and experimental therapy in transgenic models of the Alzheimer-like amyloid pathology

7 July 2018

1 reference

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Role of cyclooxygenase-2 and 5-lipoxygenase polymorphisms in Alzheimer's disease in a population from northern Italy: implication for pharmacogenomics

27 October 2018

1 reference

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Regulation of PC12 cell survival and differentiation by the new P2Y-like receptor GPR17.

27 October 2018

1 reference

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Minocycline inhibits 5-lipoxygenase expression and accelerates functional recovery in chronic phase of focal cerebral ischemia in rats

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Alterations in excitotoxicity and prostaglandin metabolism in a transgenic mouse model of Alzheimer's disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Synthesis of lipoxin A4 by 5-lipoxygenase mediates PPARgamma-dependent, neuroprotective effects of rosiglitazone in experimental stroke.

27 October 2018

1 reference

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Phosphorylation of 5-lipoxygenase at ser523 by protein kinase A determines whether pioglitazone and atorvastatin induce proinflammatory leukotriene B4 or anti-inflammatory 15-epi-lipoxin a4 production

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

The Sp1/Egr1-tandem repeat polymorphism in the 5-lipoxygenase gene promoter is not associated with late onset Alzheimer disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Leukotriene synthesis is required for hedgehog-dependent neurite projection in neuralized embryoid bodies but not for motor neuron differentiation

27 October 2018

1 reference

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Cysteinyl leukotriene receptor 1 partially mediates brain cryoinjury in mice

27 October 2018

1 reference

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Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama Study

27 October 2018

1 reference

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Leukotriene B4 and lipoxin A4 are regulatory signals for neural stem cell proliferation and differentiation

27 October 2018

1 reference

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The 5-lipoxygenase enzymatic pathway in the mouse brain: young versus old.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Minocycline protects PC12 cells against NMDA-induced injury via inhibiting 5-lipoxygenase activation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Montelukast, a cysteinyl leukotriene receptor-1 antagonist, dose- and time-dependently protects against focal cerebral ischemia in mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

5-Lipoxygenase is required for proliferation of immature cerebellar granule neurons in vitro

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Increased expression of cyclooxygenases and peroxisome proliferator-activated receptor-gamma in Alzheimer's disease brains

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033490

Transcellular biosynthesis of cysteinyl leukotrienes in rat neuronal and glial cells

27 October 2018

1 reference

12 December 2020

Inflammatory 5-LOX mRNA and protein are increased in brain of aging rats

1 reference

12 December 2020

Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer

1 reference

12 December 2020

Eicosanoids are produced by microglia, not by astrocytes, in rat glial cell cultures

1 reference

12 December 2020

10.1016/J.PNPBP.2010.07.032

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference