(Q34561569)

3 August 2017

Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources (English)

1 reference

Scheherazade Sadegh-Nasseri

3 August 2017

object named as

Scheherazade Sadegh-Nasseri

10

0 references

Rachel R. Caspi

object named as

Rachel R Caspi

8

0 references

author name string

AeRyon Kim

1

1 reference

3 August 2017

Isamu Z Hartman

2

1 reference

3 August 2017

Brad Poore

3

1 reference

3 August 2017

Tatiana Boronina

4

1 reference

3 August 2017

Robert N Cole

5

1 reference

3 August 2017

Nianbin Song

6

1 reference

3 August 2017

M Teresa Ciudad

7

1 reference

3 August 2017

Dolores Jaraquemada

9

1 reference

3 August 2017

language of work or name

English

0 references

publication date

21 November 2014

1 reference

3 August 2017

Nature Communications

1 reference

3 August 2017

5

1 reference

3 August 2017

5369

1 reference

https://scigraph.springernature.com/pub.10.1038/ncomms6369

3 August 2017

0 references

cites work

Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

HLA-DO and Its Role in MHC Class II Antigen Presentation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Pathways of antigen processing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Less label, more free: approaches in label-free quantitative mass spectrometry.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

A reductionist cell-free major histocompatibility complex class II antigen processing system identifies immunodominant epitopes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Options and considerations when selecting a quantitative proteomics strategy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Monitoring compartment-specific substrate cleavage by cathepsins B, K, L, and S at physiological pH and redox conditions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4+ T cells from a vaccinated donor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

A novel cell penetrating aspartic protease inhibitor blocks processing and presentation of tetanus toxoid more efficiently than pepstatin A.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Folding of an MHC class II-restricted tumor antigen controls its antigenicity via MHC-guided processing.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

HLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Small molecules that enhance the catalytic efficiency of HLA-DM

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Cell biology of antigen processing in vitro and in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Mhc-guided processing: binding of large antigen fragments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Biosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Creation versus destruction of T cell epitopes in the class II MHC pathway.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Epitope dominance, competition and T cell affinity maturation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Cathepsin S and an asparagine-specific endoprotease dominate the proteolytic processing of human myelin basic protein in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Defective antigen processing in GILT-free mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

HLA-DM recognizes the flexible conformation of major histocompatibility complex class II.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Cathepsins and compartmentalization in antigen presentation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Proteases involved in MHC class II antigen presentation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Role of APC in the selection of immunodominant T cell epitopes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Sodium dodecyl sulfate stability of HLA-DR1 complexes correlates with burial of hydrophobic residues in pocket 1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Myocarditis-inducing epitope of myosin binds constitutively and stably to I-Ak on antigen-presenting cells in the heart

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Interaction of peptide antigens and class II major histocompatibility complex antigens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

T cell recognition of fibrinogen. A determinant on the A alpha-chain does not require processing.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Antigen analog-major histocompatibility complexes act as antagonists of the T cell receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4241505

Memory CD8 T-cell compartment grows in size with immunological experience

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Structural basis for helper T-cell and antibody epitope immunodominance in bacteriophage T4 Hsp10. Role of disordered loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Structural intermediates in the reactions of antigenic peptides with MHC molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Pathogenic human thyroglobulin peptides in HLA-DR3 transgenic mouse model of autoimmune thyroiditis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Allocation of helper T-cell epitope immunodominance according to three-dimensional structure in the human immunodeficiency virus type I envelope glycoprotein gp120.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Activation of lysosomal function during dendritic cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Studying MHC class II peptide loading and editing in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Human T-cell clones recognize chemically synthesized peptides of influenza haemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6369

Induction of T cell anergy by low numbers of agonist ligands

21 January 2018

1 reference

12 December 2020

Capacity of intact proteins to bind to MHC class II molecules

1 reference

12 December 2020

CA074 methyl ester: a proinhibitor for intracellular cathepsin B

1 reference

12 December 2020

Intact proteins can bind to class II histocompatibility molecules with high affinity

1 reference

12 December 2020

Stable peptide binding to MHC class II molecule is rapid and is determined by a receptive conformation shaped by prior association with low affinity peptides

1 reference

12 December 2020

Large protein fragments as substrates for endocytic antigen capture by MHC class II molecules

1 reference

12 December 2020

The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance

1 reference

12 December 2020

Presentation of the Goodpasture autoantigen to CD4 T cells is influenced more by processing constraints than by HLA class II peptide binding preferences

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS6369

1 reference

Dimensions Publication ID

3 August 2017

0 references

0 references

1 reference

3 August 2017

1 reference