(Q34561910)

3 August 2017

1 reference

title

Toxicogenetics: population-based testing of drug and chemical safety in mouse models (English)

1 reference

3 August 2017

David W Threadgill

5

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Steven R Kleeberger

object named as

Steven R Kleeberger

series ordinal

4

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Daniel M Gatti

series ordinal

2

object named as

Daniel M Gatti

1 reference

3 August 2017

1

Ivan Rusyn

1 reference

3 August 2017

Timothy Wiltshire

3

1 reference

3 August 2017

publication date

1 August 2010

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3 August 2017

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3 August 2017

volume

11

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3 August 2017

issue

8

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3 August 2017

page(s)

1127-1136

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Pharmacogenomic discovery using cell-based models

3 August 2017

cites work

1 reference

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Identification of novel susceptibility genes in ozone-induced inflammation in mice

7 July 2018

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Detection, validation, and downstream analysis of allelic variation in gene expression

7 July 2018

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Finding the missing heritability of complex diseases

7 July 2018

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Drug-induced liver injury: insights from genetic studies.

7 July 2018

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Molecular networks as sensors and drivers of common human diseases

7 July 2018

1 reference

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Systems biology in pharmacogenomic research: the way to personalized prescribing?

7 July 2018

1 reference

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Pharmacogenomics of adverse drug reactions: practical applications and perspectives

7 July 2018

1 reference

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

7 July 2018

1 reference

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Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel

7 July 2018

1 reference

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Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

7 July 2018

1 reference

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Genomewide association studies and human disease

7 July 2018

1 reference

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7 July 2018

Mouse phenome database

1 reference

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Genetical genomics: spotlight on QTL hotspots

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants

7 July 2018

1 reference

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Accurate discovery of expression quantitative trait loci under confounding from spurious and genuine regulatory hotspots

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetic determinants of drug response in heart failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Controlling for false positive findings of trans-hubs in expression quantitative trait loci mapping

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Mapping the genetic architecture of gene expression in human liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Progress and prospects in rat genetics: a community view.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

An imputed genotype resource for the laboratory mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

HLA-B*5701 screening for hypersensitivity to abacavir

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Pathway analysis tools and toxicogenomics reference databases for risk assessment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

In silico and in vitro pharmacogenetic analysis in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

The polymorphism architecture of mouse genetic resources elucidated using genome-wide resequencing data: implications for QTL discovery and systems genetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Reciprocal congenic lines of mice capture the aliq1 effect on acute lung injury survival time

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Sequence polymorphisms cause many false cis eQTLs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Detection of eQTL modules mediated by activity levels of transcription factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genome-level analysis of genetic regulation of liver gene expression networks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

A framework for the use of genomics data at the EPA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

In silico pharmacogenetics of warfarin metabolism.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Associations of tumor necrosis factor G-308A with childhood asthma and wheezing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Simulating the collaborative cross: power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Intracellular signaling mechanisms of acetaminophen-induced liver cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Idiosyncratic drug hepatotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetical genomics in humans and model organisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Cis-acting expression quantitative trait loci in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

The genomes of recombinant inbred lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetic and haplotype diversity among wild-derived mouse inbred strains.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

An efficient SNP system for mouse genome scanning and elucidating strain relationships.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Statistical significance for genomewide studies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetics of gene expression surveyed in maize, mouse and man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Initial sequencing and comparative analysis of the mouse genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Alcohol and genetics: new models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Toxicogenomics: a new revolution in drug safety

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genetic dissection of transcriptional regulation in budding yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Experimental approaches to the determination of genetic variability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

The Sequence of the Human Genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Mapping mendelian factors underlying quantitative traits using RFLP linkage maps

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

A network view of disease and compound screening

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Multiple genetic loci for bone mineral density and fractures

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Naive application of permutation testing leads to inflated type I error rates

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

A sequence-based variation map of 8.27 million SNPs in inbred mouse strains

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Future of toxicogenomics and safety signatures: balancing public access to data with proprietary drug discovery

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Rat survival to anthrax lethal toxin is likely controlled by a single gene

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

An integrative genomics approach to the reconstruction of gene networks in segregating populations.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Ozone-induced acute pulmonary injury in inbred mouse strains

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Mapping of quantitative trait loci underlying ethanol metabolism in BXD recombinant inbred mouse strains

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Chloroform inhalation exposure conditions necessary to initiate liver toxicity in female B6C3F1 mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Subchronic toxicity of human immunodeficiency virus and tuberculosis combination therapies in B6C3F1 mice

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

The Collaborative Cross, a community resource for the genetic analysis of complex traits

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035927

Response to acute ozone exposure in healthy men. Results of a screening procedure

9 December 2018

1 reference

12 December 2020

Genetic analysis of ozone-induced acute lung injury in sensitive and resistant strains of mice

1 reference

12 December 2020

Characterization of inhaled alpha-methylstyrene vapor toxicity for B6C3F1 mice and F344 rats

1 reference

12 December 2020

Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors

1 reference

12 December 2020

Linkage analysis of susceptibility to ozone-induced lung inflammation in inbred mice

1 reference

12 December 2020

A simple regression method for mapping quantitative trait loci in line crosses using flanking markers

1 reference

12 December 2020

Ozone enhances markers of innate immunity and antigen presentation on airway monocytes in healthy individuals

1 reference

12 December 2020

Genomewide association studies--illuminating biologic pathways

1 reference

12 December 2020

Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis

1 reference

12 December 2020

Empowering microarrays in the regulatory setting

1 reference

12 December 2020

Identifiers

DOI

10.2217/PGS.10.100

1 reference

3 August 2017

1 reference

3 August 2017

1 reference