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Biotechnologies and therapeutics: chromatin as a target.
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Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
review article
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Europe PubMed Central
title
Biotechnologies and therapeutics: chromatin as a target
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
main subject
biotechnology
0 references
author
Philip D Gregory
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Fyodor Urnov
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3
object named as
Fyodor D Urnov
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
Andreas Reik
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
publication date
1 April 2002
1 reference
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Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
12
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
233-242
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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Histone deacetylase as a therapeutic target
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DNA methylation in health and disease
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7 January 2021
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Inhibitors of histone deacetylase as new anticancer agents
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7 January 2021
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Histone deacetylase inhibitors as new cancer drugs
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7 January 2021
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Antitumor properties of 2(1H)-pyrimidinone riboside (zebularine) and its fluorinated analogues.
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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
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7 January 2021
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A positive role for histone acetylation in transcription factor access to nucleosomal DNA
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7 January 2021
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Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain
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7 January 2021
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Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter
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7 January 2021
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Regulation of embryonic/fetal globin genes by nuclear hormone receptors: a novel perspective on hemoglobin switching.
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An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells
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7 January 2021
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Unanticipated repression function linked to erythroid Krüppel-like factor
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Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin
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The language of covalent histone modifications
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CREB-Binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites
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Stimulation of NF-E2 DNA binding by CREB-binding protein (CBP)-mediated acetylation
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7 January 2021
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Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases
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7 January 2021
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Regulation of activity of the transcription factor GATA-1 by acetylation
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7 January 2021
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Phosphorylation of GATA-1 increases its DNA-binding affinity and is correlated with induction of human K562 erythroleukaemia cells
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Mechanism for fetal globin gene expression: role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway
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Short-chain fatty acid derivatives stimulate cell proliferation and induce STAT-5 activation
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7 January 2021
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Loss of PU.1 expression following inhibition of histone deacetylases
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7 January 2021
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Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase
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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
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Crossref
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7 January 2021
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Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation
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Position-independent, high-level expression of the human beta-globin gene in transgenic mice
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7 January 2021
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Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structure
1 reference
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Crossref
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7 January 2021
based on heuristic
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Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The beta-globin locus control region versus gene therapy vectors: a struggle for expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-globin YAC transgenes exhibit uniform expression levels but position effect variegation in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The protein CTCF is required for the enhancer blocking activity of vertebrate insulators
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The cHS4 insulator increases the probability of retroviral expression at random chromosomal integration sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A chromatin insulator protects retrovirus vectors from chromosomal position effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Position-independent human beta-globin gene expression mediated by a recombinant adeno-associated virus vector carrying the chicken beta-globin insulator
1 reference
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Crossref
reference URL
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7 January 2021
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Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells
1 reference
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7 January 2021
based on heuristic
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Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides
1 reference
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7 January 2021
based on heuristic
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DNA recognition by Cys2His2 zinc finger proteins
1 reference
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Crossref
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7 January 2021
based on heuristic
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Expressing the human genome
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Design and selection of novel Cys2His2 zinc finger proteins
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Positive and negative regulation of endogenous genes by designed transcription factors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear cloning and epigenetic reprogramming of the genome
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prospects for the use of nuclear transfer in human transplantation
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Production of cloned pigs from in vitro systems.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human factor IX transgenic sheep produced by transfer of nuclei from transfected fetal fibroblasts
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic rescue of an endangered mammal by cross-species nuclear transfer using post-mortem somatic cells.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Imprinting and the epigenetic asymmetry between parental genomes.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic instability in ES cells and cloned mice.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Generation of mice from wild-type and targeted ES cells by nuclear cloning.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Factors affecting the developmental potential of cloned mammalian embryos
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Typical demethylation events in cloned pig embryos. Clues on species-specific differences in epigenetic reprogramming of a cloned donor genome.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant methylation of donor genome in cloned bovine embryos.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of male germ cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic reprogramming in mammalian development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active demethylation of the paternal genome in the mouse zygote
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active remodeling of somatic nuclei in egg cytoplasm by the nucleosomal ATPase ISWI
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Widespread collaboration of Isw2 and Sin3-Rpd3 chromatin remodeling complexes in transcriptional repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental biology. Don't clone humans!
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The plasticity of dendritic cell responses to pathogens and their components
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifying regulatory networks by combinatorial analysis of promoter elements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of in vivo DNA targets of chromatin proteins using tethered dam methyltransferase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromatin profiling using targeted DNA adenine methyltransferase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correction of sickle cell disease in transgenic mouse models by gene therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a small molecule inhibitor of Sir2p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PPARgamma knockdown by engineered transcription factors: exogenous PPARgamma2 but not PPARgamma1 reactivates adipogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic reprogramming of DNA methylation in the early mouse embryo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide methylation patterns in normal and uniparental early mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2802%2900291-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-437X(02)00291-5
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed ID
11893498
1 reference
stated in
Europe PubMed Central
PubMed ID
11893498
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11893498%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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