(Q34581761)

3 August 2017

title

ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells (English)

1 reference

3 August 2017

1 reference

Kristin A D Sauter

1

1 reference

3 August 2017

Eli A Magun

series ordinal

2

1 reference

3 August 2017

Mihail S Iordanov

series ordinal

3

1 reference

3 August 2017

Bruce E Magun

series ordinal

4

1 reference

3 August 2017

publication date

13 August 2010

1 reference

Cancer Biology and Therapy

3 August 2017

published in

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3 August 2017

volume

10

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3 August 2017

issue

3

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3 August 2017

page(s)

258-266

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Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers.

3 August 2017

cites work

1 reference

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Anti-Fas gene therapy prevents doxorubicin-induced acute cardiotoxicity through mechanisms independent of apoptosis

7 July 2018

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Extended kinase profile and properties of the protein kinase inhibitor nilotinib

7 July 2018

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Protective effect of tetrahydroxystilbene glucoside on cardiotoxicity induced by doxorubicin in vitro and in vivo

7 July 2018

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Plumbagin induces ROS-mediated apoptosis in human promyelocytic leukemia cells in vivo

7 July 2018

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Sorafenib: a review of its use in advanced hepatocellular carcinoma

7 July 2018

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Small molecule p38 MAP kinase inhibitors for the treatment of inflammatory diseases: novel structures and developments during 2006-2008.

7 July 2018

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NF-kappaB signaling pathway and its therapeutic implications in human diseases

7 July 2018

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Inhibition of p38 MAPK suppresses inflammatory cytokine induction by etoposide, 5-fluorouracil, and doxorubicin without affecting tumoricidal activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

ZAK: a MAP3Kinase that transduces Shiga toxin- and ricin-induced proinflammatory cytokine expression.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

A quantitative analysis of kinase inhibitor selectivity

7 July 2018

1 reference

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Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks

7 July 2018

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Inhibitors of c-Jun N-terminal kinases: JuNK no more?

7 July 2018

1 reference

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c-Jun N-terminal kinases as potential therapeutic targets

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

p38 pathway kinases as anti-inflammatory drug targets

7 July 2018

1 reference

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In vitro and in vivo immunosuppressive activity of a novel anthracycline, 13-deoxy, 5-iminodoxorubicin.

7 July 2018

1 reference

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Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Cancer chemotherapy-related symptoms: evidence to suggest a role for proinflammatory cytokines.

7 July 2018

1 reference

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Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Doxorubicin-induced cardiac mitochondrionopathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Mixed-lineage kinase control of JNK and p38 MAPK pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Doxorubicin-induced apoptosis: implications in cardiotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Adriamycin-induced heart failure: mechanism and modulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Different mechanisms of c-Jun NH(2)-terminal kinase-1 (JNK1) activation by ultraviolet-B radiation and by oxidative stressors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Loss of cellular K+ mimics ribotoxic stress. Inhibition of protein synthesis and activation of the stress kinases SEK1/MKK4, stress-activated protein kinase/c-Jun NH2-terminal kinase 1, and p38/HOG1 by palytoxin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3040836

Protective effect of creatine against RNA damage.

7 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.3.12367

Ultraviolet radiation triggers the ribotoxic stress response in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.3.12367

Silymarin modulates doxorubicin-induced oxidative stress, Bcl-xL and p53 expression while preventing apoptotic and necrotic cell death in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.3.12367

Pretreatment with statin attenuates the cardiotoxicity of Doxorubicin in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FCBT.10.3.12367

MAPK superfamily plays an important role in daunomycin-induced apoptosis of cardiac myocytes

21 January 2018

1 reference

12 December 2020

Structural change of ribosomes during apoptosis: degradation and externalization of ribosomal proteins in doxorubicin-treated Jurkat cells

1 reference

12 December 2020

Doxorubicin-Induced MAPK Activation in Hepatocyte Cultures Is Independent of Oxidant Damage

1 reference

12 December 2020

New Bcr-Abl inhibitors in chronic myeloid leukemia: keeping resistance in check

1 reference

12 December 2020

1 reference

12 December 2020

Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases

1 reference

12 December 2020

Identifiers

DOI

10.4161/CBT.10.3.12367

1 reference

3 August 2017

1 reference

3 August 2017

1 reference