(Q34592072)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

A ring-distortion strategy to construct stereochemically complex and structurally diverse compounds from natural products (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Robert W Huigens

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Karen C Morrison

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Robert W Hicklin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Timothy A Flood

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Paul J Hergenrother

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

1 reference

20 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

195-202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

Charting, navigating, and populating natural product chemical space for drug discovery

24 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Natural products as sources of new drugs over the 30 years from 1981 to 2010

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

A biomimetic polyketide-inspired approach to small-molecule ligand discovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Remodelling of the natural product fumagillol employing a reaction discovery approach

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

New perspectives of gibberellic acid production: a review.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

The influence of the 'organizational factor' on compound quality in drug discovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

The rise, fall and reinvention of combinatorial chemistry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

How were new medicines discovered?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Creation and manipulation of common functional groups en route to a skeletally diverse chemical library

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Rational methods for the selection of diverse screening compounds

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Extended-connectivity fingerprints

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Small molecular weight protein-protein interaction antagonists: an insurmountable challenge?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Rabe Rest in Peace: Confirmation of the Rabe–Kindler Conversion ofd-Quinotoxine Into Quinine: Experimental Affirmation of the Woodward–Doering Formal Total Synthesis of Quinine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

A Computer Program for Classifying Plants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Drugs for bad bugs: confronting the challenges of antibacterial discovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Chemistry and biology of monoterpene indole alkaloid biosynthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Synthesis of a 10,000-membered library of molecules resembling carpanone and discovery of vesicular traffic inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Target-oriented and diversity-oriented organic synthesis in drug discovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Synthetic strategies in combinatorial chemistry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3965367

Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

A microwave promoted and Lewis acid catalysed solventless approach to 4-azasteroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

What do medicinal chemists actually make? A 50-year retrospective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

Escape from flatland: increasing saturation as an approach to improving clinical success.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

The influence of drug-like concepts on decision-making in medicinal chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

A Possible Mechanism for Biological and Chemical Activity of Gibberellic Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

Tackling transcription factors: challenges in antitumor therapy

21 January 2018

1 reference

12 December 2020

Solvent-controlled leaving-group selectivity in aromatic nucleophilic substitution

1 reference

12 December 2020

Physicochemical properties of antibacterial compounds: implications for drug discovery

1 reference

12 December 2020

1 reference

12 December 2020

Small-molecule diversity using a skeletal transformation strategy

1 reference

12 December 2020

Improved addition of organolithium reagents to hindered and/or enolisable ketones

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

7 January 2021

inferred from DOI database lookup

Cinchona Alkaloids in Synthesis and Catalysis

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

7 January 2021

inferred from DOI database lookup

Nucleophilic Addition of Organometallic Reagents to Cinchona Alkaloids: Simple Access to Diverse Architectures

1 reference

https://api.crossref.org/works/10.1038%2FNCHEM.1549

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEM.1549

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

23422561

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23422561%20AND%20SRC:MED&resulttype=core&format=json