(Q34616432)

3 August 2017

1 reference

title

Stepping up melanocytes to the challenge of UV exposure (English)

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3 August 2017

1

Zalfa A Abdel-Malek

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3 August 2017

Ana Luisa Kadekaro

2

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3 August 2017

Viki B Swope

series ordinal

3

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3 August 2017

publication date

1 February 2010

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Pigment Cell & Melanoma Research

3 August 2017

published in

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3 August 2017

volume

23

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3 August 2017

issue

2

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3 August 2017

page(s)

171-186

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Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides

3 August 2017

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Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes

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Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair

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MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations

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PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

21 January 2018

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A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

21 January 2018

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Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase

21 January 2018

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Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

21 January 2018

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Photodestruction of pheomelanin: role of oxygen

21 January 2018

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Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response

21 January 2018

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Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA.

21 January 2018

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UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53.

21 January 2018

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Defective Repair Replication of DNA in Xeroderma Pigmentosum

21 January 2018

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Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Central role of p53 in the suntan response and pathologic hyperpigmentation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Mutations of the BRAF gene in human cancer

21 January 2018

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NF-kappa B activation by ultraviolet light not dependent on a nuclear signal.

21 January 2018

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Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning

21 January 2018

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Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

21 January 2018

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Wavelength dependence of pyrimidine dimer formation in DNA of human skin irradiated in situ with ultraviolet light

21 January 2018

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Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation

21 January 2018

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The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

UVA effects on mammalian skin and cells

21 January 2018

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Transcriptome analysis reveals cyclobutane pyrimidine dimers as a major source of UV-induced DNA breaks

21 January 2018

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Mechanisms of ultraviolet light-induced pigmentation

21 January 2018

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The pathogenesis of melanoma induced by ultraviolet radiation

21 January 2018

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NF-kappaB activation by reactive oxygen species: fifteen years later

21 January 2018

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Sunburn and malignant melanoma

21 January 2018

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The SCF/KIT pathway plays a critical role in the control of normal human melanocyte homeostasis

21 January 2018

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Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4(R24C/R24C)/Tyr-Nras(Q61K) mice following neonatal UVR.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Skin cancer in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Transcription-coupled DNA repair: two decades of progress and surprises

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Molecular pathogenesis of cutaneous melanocytic neoplasms

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

21 January 2018

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Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response

21 January 2018

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A polymorphism in the agouti signaling protein gene is associated with human pigmentation

21 January 2018

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Tyrosinase gene expression is regulated by p53.

21 January 2018

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Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology

21 January 2018

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Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

21 January 2018

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Supranuclear melanin caps reduce ultraviolet induced DNA photoproducts in human epidermis

21 January 2018

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Functional genomics of UV radiation responses in human cells

21 January 2018

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Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light

21 January 2018

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Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin

21 January 2018

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The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm

21 January 2018

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Sun exposure and non-melanocytic skin cancer

21 January 2018

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Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

21 January 2018

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DNA glycosylases in the base excision repair of DNA

21 January 2018

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Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation

21 January 2018

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Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation.

21 January 2018

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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

21 January 2018

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DNA repair, dysplastic nevi, and sunlight sensitivity in the development of cutaneous malignant melanoma

21 January 2018

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Microarray analysis sheds light on the dedifferentiating role of agouti signal protein in murine melanocytes via the Mc1r

21 January 2018

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Increasing burden of melanoma in the United States

21 January 2018

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MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

21 January 2018

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

21 January 2018

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Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling

21 January 2018

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Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-kappaB signaling in human epidermal keratinocytes

21 January 2018

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Correlation between melanogenic and catalase activity in in vitro human melanocytes: a synergic strategy against oxidative stress.

21 January 2018

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The significance of Nrf2 pathway in (photo)-oxidative stress response in melanocytes and keratinocytes of the human epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

21 January 2018

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Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

21 January 2018

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Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Relative induction of cyclobutane dimers and cytosine photohydrates in DNA irradiated in vitro and in vivo with ultraviolet-C and ultraviolet-B light

21 January 2018

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Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

21 January 2018

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The cloning of a family of genes that encode the melanocortin receptors

21 January 2018

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21 January 2018

Melanoma and genetics

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Human melanocytes expressing MC1R variant alleles show impaired activation of multiple signaling pathways.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

UV as an amplifier rather than inducer of NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype?

21 January 2018

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Forskolin protects keratinocytes from UVB-induced apoptosis and increases DNA repair independent of its effects on melanogenesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

alpha-Melanocyte-stimulating hormone signaling regulates expression of microphthalmia, a gene deficient in Waardenburg syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

UV damage and DNA repair in malignant melanoma and nonmelanoma skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Activation of the Mitf promoter by lipid-stimulated activation of p38-stress signalling to CREB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Role of oxidative stress and the antioxidant network in cutaneous carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Properties and function of the ocular melanin--a photobiophysical view

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

The base excision repair pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

The INK4a/ARF locus and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Repeated ultraviolet exposure affords the same protection against DNA photodamage and erythema in human skin types II and IV but is associated with faster DNA repair in skin type IV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanin offers protection against induction of cyclobutane pyrimidine dimers and 6-4 photoproducts by UVB in cultured human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanocortin 1 receptor variants in an Irish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanocortin-1 receptor signaling markedly induces the expression of the NR4A nuclear receptor subgroup in melanocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanocortin receptor-1 gene polymorphisms and the risk of cutaneous melanoma in a low-risk southern European population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Agouti signaling protein inhibits melanogenesis and the response of human melanocytes to alpha-melanotropin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Mitogen- and ultraviolet-B-induced signaling pathways in normal human melanocytes

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Nucleotide excision repair gene XPD polymorphisms and genetic predisposition to melanoma

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Identification by cDNA microarray technology of genes modulated by artificial ultraviolet radiation in normal human melanocytes: relation to melanocarcinogenesis.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Mutational analysis of the human p53 gene in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Loss of tumor suppressor p53 decreases PTEN expression and enhances signaling pathways leading to activation of activator protein 1 and nuclear factor kappaB induced by UV radiation

21 January 2018

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Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Regulation of p53 responses by post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

An L1 element intronic insertion in the black-eyed white (Mitf[mi-bw]) gene: the loss of a single Mitf isoform responsible for the pigmentary defect and inner ear deafness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Expression profiling of UVB response in melanocytes identifies a set of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

The increase of cell-membranous phosphatidylcholines containing polyunsaturated fatty acid residues induces phosphorylation of p53 through activation of ATR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Impaired Processing of DNA Photoproducts and Ultraviolet Hypermutability With Loss of p16INK4a or p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

Melanocortin 1 Receptor (MC1R) Gene Variants are Associated with an Increased Risk for Cutaneous Melanoma Which is Largely Independent of Skin Type and Hair Color

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2010.00679.X

10.1111/J.1755-148X.2010.00679.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference