(Q34666349)

3 August 2017

title

A discrete affinity-driven elevation of ZAP-70 kinase activity initiates negative selection (English)

1 reference

3 August 2017

Michel Mallaun

1

1 reference

3 August 2017

Gerhard Zenke

series ordinal

2

1 reference

3 August 2017

Ed Palmer

series ordinal

3

1 reference

3 August 2017

publication date

14 October 2010

1 reference

Journal of Receptors and Signal Transduction

3 August 2017

published in

1 reference

3 August 2017

volume

30

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3 August 2017

issue

6

1 reference

3 August 2017

page(s)

430-443

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Tailoring T-cell receptor signals by proximal negative feedback mechanisms

3 August 2017

cites work

1 reference

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7 July 2018

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Opposing functions of the T cell receptor kinase ZAP-70 in immunity and tolerance differentially titrate in response to nucleotide substitutions.

7 July 2018

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Structural basis for the inhibition of tyrosine kinase activity of ZAP-70

7 July 2018

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7 July 2018

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Altered peptide ligands induce delayed CD8-T cell receptor interaction--a role for CD8 in distinguishing antigen quality

7 July 2018

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7 July 2018

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Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection

7 July 2018

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Tec family kinases modulate thresholds for thymocyte development and selection

7 July 2018

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Tyrosine 319 in the interdomain B of ZAP-70 is a binding site for the Src homology 2 domain of Lck

7 July 2018

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7 July 2018

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Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

7 July 2018

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7 July 2018

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A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development

7 July 2018

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7 July 2018

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Mechanism of activation for Zap-70 catalytic activity

7 July 2018

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Distinct tyrosine phosphorylation sites in ZAP-70 mediate activation and negative regulation of antigen receptor function

7 July 2018

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Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling

7 July 2018

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T-cell-receptor affinity and thymocyte positive selection

7 July 2018

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Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells

7 July 2018

1 reference

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T cell receptor antagonist peptides induce positive selection

7 July 2018

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Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

7 July 2018

1 reference

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Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function

7 July 2018

1 reference

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Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

7 July 2018

1 reference

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Essential role for ZAP-70 in both positive and negative selection of thymocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

Evidence for a differential avidity model of T cell selection in the thymus

7 July 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

Dephosphorylation of ZAP-70 and inhibition of T cell activation by activated SHP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3056388

Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling

26 October 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2010.518151

A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor

21 January 2018

1 reference

12 December 2020

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

12 December 2020

Tyrosine 319, a newly identified phosphorylation site of ZAP-70, plays a critical role in T cell antigen receptor signaling

1 reference

12 December 2020

Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity

1 reference

12 December 2020

10.3109/10799893.2010.518151

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference