(Q34669736)

3 August 2017

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title

Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses (English)

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3 August 2017

Adolfo García-Sastre

1

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publication date

1 May 2002

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3 August 2017

Microbes and Infection

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3 August 2017

4

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3 August 2017

647-655

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3 August 2017

6

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Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The human interferon alpha/beta receptor: characterization and molecular cloning

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

How cells respond to interferons

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

PKR; a sentinel kinase for cellular stress

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The human 2',5'-oligoadenylate synthetase family: interferon-induced proteins with unique enzymatic properties

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

A Specific Isozyme of 2′-5′ Oligoadenylate Synthetase Is a Dual Function Proapoptotic Protein of the Bcl-2 Family

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

MxA GTPase blocks reporter gene expression of reconstituted Thogoto virus ribonucleoprotein complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Role of the promyelocytic leukemia protein PML in the interferon sensitivity of lymphocytic choriomeningitis virus

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

A new pathway of translational regulation mediated by eukaryotic initiation factor 3

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Interferon treatment of mice: enhanced expression of histocompatibility antigens on lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Gene induction pathways mediated by distinct IRFs during viral infection.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Vaccinia virus B18R gene encodes a type I interferon-binding protein that blocks interferon alpha transmembrane signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The vaccinia virus E3L gene product interacts with both the regulatory and the substrate binding regions of PKR: implications for PKR autoregulation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Vaccinia virus-encoded elF-2α homolog abrogates the antiviral effect of interferon

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Activation of the ppp(A2'p)nA system in interferon-treated, herpes simplex virus-infected cells and evidence for novel inhibitors of the ppp(A2'p)nA-dependent RNase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Use of differential display analysis to assess the effect of human cytomegalovirus infection on the accumulation of cellular RNAs: induction of interferon-responsive RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Cellular gene expression altered by human cytomegalovirus: global monitoring with oligonucleotide arrays

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Characterization of a novel human herpesvirus 8-encoded protein, vIRF-3, that shows homology to viral and cellular interferon regulatory factors

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Latently expressed human herpesvirus 8-encoded interferon regulatory factor 2 inhibits double-stranded RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Direct suppression of Stat1 function during adenoviral infection

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Binding of influenza A virus NS1 protein to dsRNA in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Binding of the influenza virus NS1 protein to double-stranded RNA inhibits the activation of the protein kinase that phosphorylates the elF-2 translation initiation factor

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Interaction of the interferon-induced PKR protein kinase with inhibitory proteins P58IPK and vaccinia virus K3L is mediated by unique domains: implications for kinase regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Sendai virus C proteins counteract the interferon-mediated induction of an antiviral state

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Sendai virus C proteins must interact directly with cellular components to interfere with interferon action

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Sendai virus blocks alpha interferon signaling to signal transducers and activators of transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Sendai virus C protein physically associates with Stat1.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral response

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSs

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The Ebola virus VP35 protein functions as a type I IFN antagonist.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Identification of the hepatitis B virus factor that inhibits expression of the beta interferon gene

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The polyoma virus T antigen interferes with interferon-inducible gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Poliovirus 3A protein limits interleukin-6 (IL-6), IL-8, and beta interferon secretion during viral infection

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Ability of foot-and-mouth disease virus to form plaques in cell culture is associated with suppression of alpha/beta interferon.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The leader protein of Theiler's virus inhibits immediate-early alpha/beta interferon production

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The human papilloma virus (HPV)-18 E6 oncoprotein physically associates with Tyk2 and impairs Jak-STAT activation by interferon-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Inhibitory activity for the interferon-induced protein kinase is associated with the reovirus serotype 1 sigma 3 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Evasion of host defenses by measles virus: wild-type measles virus infection interferes with induction of Alpha/Beta interferon production

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon response

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

C terminal CYS-RICH region of mumps virus structural V protein correlates with block of interferon alpha and gamma signal transduction pathway through decrease of STAT 1-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1286-4579%2802%2901583-6

7 January 2021

10.1016/S1286-4579(02)01583-6

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12048034