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Insulin resistance and pancreatic beta cell failure
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Insulin resistance and pancreatic beta cell failure
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
main subject
preproinsulin
1 reference
based on heuristic
inferred from title
insulin resistance
1 reference
based on heuristic
inferred from title
author name string
Masato Kasuga
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
language of work or name
English
0 references
publication date
1 July 2006
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
volume
116
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
issue
7
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
page(s)
1756-1760
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
cites work
Insulin resistance and atherosclerosis
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PubMed Central
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Islet beta cell failure in type 2 diabetes
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PubMed Central
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7 July 2018
Inflammation and insulin resistance
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PubMed Central
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7 July 2018
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
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7 July 2018
AMP-activated protein kinase signaling in metabolic regulation
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7 July 2018
Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony
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7 July 2018
Central insulin action in energy and glucose homeostasis
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MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
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7 July 2018
Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
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PubMed Central
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7 July 2018
Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes
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7 July 2018
CCR2 modulates inflammatory and metabolic effects of high-fat feeding
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PubMed Central
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7 July 2018
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
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PubMed Central
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7 July 2018
Mitochondrial dysfunction and type 2 diabetes
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7 July 2018
Increased oxidative stress in obesity and its impact on metabolic syndrome
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7 July 2018
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
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7 July 2018
Why does diabetes increase atherosclerosis? I don't know!
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PubMed Central
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7 July 2018
Transgenic rescue of insulin receptor-deficient mice
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PubMed Central
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7 July 2018
Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle
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7 July 2018
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
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7 July 2018
Obesity is associated with macrophage accumulation in adipose tissue
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7 July 2018
Importance of Weight Management in Type 2 Diabetes: Review with Meta-analysis of Clinical Studies
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PubMed Central
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7 July 2018
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
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7 July 2018
Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
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7 July 2018
Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
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7 July 2018
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance
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PubMed Central
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7 July 2018
Induction of cachexia in mice by systemically administered myostatin.
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7 July 2018
Angptl3 regulates lipid metabolism in mice
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PubMed Central
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7 July 2018
Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
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7 July 2018
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
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PubMed Central
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7 July 2018
Role of brain insulin receptor in control of body weight and reproduction
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7 July 2018
Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
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7 July 2018
Disruption of IRS-2 causes type 2 diabetes in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
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7 July 2018
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Angiopoietin-related growth factor antagonizes obesity and insulin resistance.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Hypothalamic insulin signaling is required for inhibition of glucose production
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483164
retrieved
26 October 2018
A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16823472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16823472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16823472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16823472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/16823472
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI29189
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
PMCID
1483164
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
PubMed ID
16823472
1 reference
stated in
Europe PubMed Central
PubMed ID
16823472
retrieved
4 August 2017
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