(Q34707190)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

0 references

1 reference

chronic lymphocytic leukemia

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Giovanni Monaco

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jan B. Parys

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Fei Zhong

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Michael W Harr

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Humbert De Smedt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Yi-Ping Rong

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jason K Molitoris

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Minh Lam

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Christopher Ryder

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Shigemi Matsuyama

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Clark W Distelhorst

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

30 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

2924-2934

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

19 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3062302/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Chronic lymphocytic leukemia: interplay between noncoding RNAs and protein-coding genes

7 July 2018

1 reference

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The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

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7 July 2018

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Small-molecule Bcl-2 antagonists as targeted therapy in oncology

7 July 2018

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The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family.

7 July 2018

1 reference

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Bcl-2 family proteins and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

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7 July 2018

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Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals

7 July 2018

1 reference

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Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

7 July 2018

1 reference

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Diagnosing and exploiting cancer's addiction to blocks in apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

The BCL-2 protein family: opposing activities that mediate cell death

7 July 2018

1 reference

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B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Bcl-2 protein family members: versatile regulators of calcium signaling in cell survival and apoptosis

7 July 2018

1 reference

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Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating.

7 July 2018

1 reference

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Mitochondrial Ca2+ as a key regulator of cell life and death

7 July 2018

1 reference

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Inositol trisphosphate receptor Ca2+ release channels.

7 July 2018

1 reference

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The Bcl-2 apoptotic switch in cancer development and therapy

7 July 2018

1 reference

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IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond

7 July 2018

1 reference

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SVM-based prediction of caspase substrate cleavage sites

7 July 2018

1 reference

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Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

7 July 2018

1 reference

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Structural and functional features and significance of the physical linkage between ER and mitochondria.

7 July 2018

1 reference

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Bcl-2 and Ca2+ homeostasis in the endoplasmic reticulum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Bcl-2 differentially regulates Ca2+ signals according to the strength of T cell receptor activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

7 July 2018

1 reference

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The endoplasmic reticulum gateway to apoptosis by Bcl-X(L) modulation of the InsP3R

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

miR-15 and miR-16 induce apoptosis by targeting BCL2

7 July 2018

1 reference

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The inositol 1,4,5-trisphosphate receptors

7 July 2018

1 reference

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Regulation of cell death: the calcium-apoptosis link

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Calcium signalling: dynamics, homeostasis and remodelling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Propagation of the apoptotic signal by mitochondrial waves

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Calcium signaling mechanisms in T lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Apoptosis driven by IP(3)-linked mitochondrial calcium signals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Bcl-2 suppresses Ca2+ release through inositol 1,4,5-trisphosphate receptors and inhibits Ca2+ uptake by mitochondria without affecting ER calcium store content

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Endocytosis targets exogenous material selectively to cathepsin S in live human dendritic cells, while cell-penetrating peptides mediate nonselective transport to cysteine cathepsins.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062302

Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21193695

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21193695

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2010-09-307405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21193695%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

21193695

1 reference