(Q34718257)

4 August 2017

title

Impairment of mitochondria in adult mouse brain overexpressing predominantly full-length, N-terminally acetylated human α-synuclein (English)

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4 August 2017

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4

Eliezer Masliah

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4 August 2017

6

Harry V Vinters

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4 August 2017

9

Julian P Whitelegge

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4 August 2017

7

Gary W Mathern

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4 August 2017

Theodore A Sarafian

1

1 reference

4 August 2017

Christopher M Ryan

2

1 reference

4 August 2017

Puneet Souda

3

1 reference

4 August 2017

Upendra K Kar

5

1 reference

4 August 2017

Kym F Faull

8

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4 August 2017

Joseph B Watson

10

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4 August 2017

language of work or name

English

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publication date

7 May 2013

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4 August 2017

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4 August 2017

volume

8

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4 August 2017

issue

5

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4 August 2017

page(s)

e63557

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Creative Commons Attribution 4.0 International

4 August 2017

copyright license

start time

7 May 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3646806/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein

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Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein

7 July 2018

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alpha-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

7 July 2018

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Behavioral and histopathological consequences of paraquat intoxication in mice: effects of alpha-synuclein over-expression

7 July 2018

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The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein

7 July 2018

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Inhaled marijuana smoke disrupts mitochondrial energetics in pulmonary epithelial cells in vivo

7 July 2018

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Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

7 July 2018

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Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein

7 July 2018

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Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

7 July 2018

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Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

7 July 2018

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Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

7 July 2018

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Parkinson's disease: mechanisms and models

7 July 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

7 July 2018

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Staging of brain pathology related to sporadic Parkinson's disease

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

alpha-synuclein promotes mitochondrial deficit and oxidative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Dendritic translocation of RC3/neurogranin mRNA in normal aging, Alzheimer disease and fronto-temporal dementia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Mitochondrial complex I deficiency in Parkinson's disease

7 July 2018

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The rat brain synucleins; family of proteins transiently associated with neuronal membrane

7 July 2018

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The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

7 July 2018

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A combinatorial code for the interaction of alpha-synuclein with membranes

21 January 2018

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Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria

21 January 2018

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Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063557

α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063557

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

21 January 2018

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21 January 2018

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Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

21 January 2018

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Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

21 January 2018

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Alpha-synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: implications in Parkinson's disease.

21 January 2018

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Synaptoneurosome micromethod for fractionation of mouse and human brain, and primary neuronal cultures.

21 January 2018

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Age-dependent modulation of hippocampal long-term potentiation by antioxidant enzymes

21 January 2018

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Cysteine string protein beta is prominently associated with nerve terminals and secretory organelles in mouse brain.

21 January 2018

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α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3646806

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23667637

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0063557

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference