(Q34801388)

English

Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Yoshikazu Takada

object named as

Yoshikazu Takada

8

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author name string

Masaaki Fujita

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Kan Zhu

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Chitose K Fujita

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Min Zhao

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Kit S Lam

5

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Mark J Kurth

6

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Yoko K Takada

7

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

language of work or name

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publication date

14 November 2014

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

290

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

259-271

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

The chemokine fractalkine can activate integrins without CX3CR1 through direct binding to a ligand-binding site distinct from the classical RGD-binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Complete integrin headpiece opening in eight steps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

A dominant-negative FGF1 mutant (the R50E mutant) suppresses tumorigenesis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Insulin-like growth factor (IGF) signaling requires αvβ3-IGF1-IGF type 1 receptor (IGF1R) ternary complex formation in anchorage independence, and the complex formation does not require IGF1R and Src activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Integrins αvβ3 and α4β1 act as coreceptors for fractalkine, and the integrin-binding defective mutant of fractalkine is an antagonist of CX3CR1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Cross-talk between integrin α6β4 and insulin-like growth factor-1 receptor (IGF1R) through direct α6β4 binding to IGF1 and subsequent α6β4-IGF1-IGF1R ternary complex formation in anchorage-independent conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Direct binding of the EGF-like domain of neuregulin-1 to integrins ({alpha}v{beta}3 and {alpha}6{beta}4) is involved in neuregulin-1/ErbB signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

A novel fibroblast growth factor-1 (FGF1) mutant that acts as an FGF antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Catalytic and non-catalytic functions of human IIA phospholipase A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Crystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

The direct binding of insulin-like growth factor-1 (IGF-1) to integrin alphavbeta3 is involved in IGF-1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Direct binding of integrin alphavbeta3 to FGF1 plays a role in FGF1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Structural basis of integrin regulation and signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Oncogenic action of phospholipase A2 in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Oncogenic action of secreted phospholipase A2 in prostate cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Type II secretory phospholipase A2 in cardiovascular disease: a mediator in atherosclerosis and ischemic damage to cardiomyocytes?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Integrins: bidirectional, allosteric signaling machines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Biological effects of secretory phospholipase A(2) group IIA on lipoproteins and in atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Expression of group IIA secretory phospholipase A2 is elevated in prostatic intraepithelial neoplasia and adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Crystal structure of the extracellular segment of integrin alpha Vbeta3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Superactivation of integrin alphavbeta3 by low antagonist concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Specific binding of integrin alpha v beta 3 to the fibrinogen gamma and alpha E chain C-terminal domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Both group IB and group IIA secreted phospholipases A2 are natural ligands of the mouse 180-kDa M-type receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Secretory phospholipase A2 is the principal bactericide for staphylococci and other gram-positive bacteria in human tears

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Cloning and expression of a membrane receptor for secretory phospholipases A2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Identification of the binding domain for secretory phospholipases A2 on their M-type 180-kDa membrane receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281730

8 July 2018

Secretory phospholipases A2 activate selective functions in human eosinophils

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.579946

21 January 2018

Identification of amino acid sequences in fibrinogen gamma -chain and tenascin C C-terminal domains critical for binding to integrin alpha vbeta 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.579946

21 January 2018

A new model of dual interacting ligand binding sites on integrin alphaIIbbeta3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.579946

21 January 2018

Impact of a soluble phospholipase A2 inhibitor on inhaled allergen challenge in subjects with asthma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.579946

21 January 2018

Conformational Changes in the Integrin βA Domain Provide a Mechanism for Signal Transduction via Hybrid Domain Movement

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.579946

21 January 2018

Group II PLA(2) content of tears in normal subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of extracellular phospholipase A2 in rheumatoid synovial fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of group 2 phospholipase A2 by lacrimal glands

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of group II phospholipase A2 and lysozyme in lacrimal glands

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cyclooxygenase-2 by secretory phospholipases A2 in nerve growth factor-stimulated rat serosal mast cells is facilitated by interaction with fibroblasts and mediated by a mechanism independent of their enzymatic functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, double-blinded, placebo-controlled clinical trial of LY333013, a selective inhibitor of group II secretory phospholipase A2, in the treatment of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25398877

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.579946

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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