(Q34819148)

4 August 2017

1 reference

title

Heterocyclic aromatic amine metabolism, DNA adduct formation, mutagenesis, and carcinogenesis (English)

1 reference

4 August 2017

1 reference

Robert J Turesky

1

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PubMed ID

12214671

4 August 2017

language of work or name

English

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publication date

1 August 2002

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4 August 2017

Drug Metabolism Reviews

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4 August 2017

34

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4 August 2017

625-650

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4 August 2017

3

1 reference

Past, present, and future of mutagens in cooked foods

4 August 2017

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Detection of a carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), in cigarette smoke condensate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Carcinogenic factors in food with relevance to colon cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Overview of carcinogenic heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Nutrition and colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Diet, nutrition, and avoidable cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Some perspectives on the nutritional aspects of breast cancer research. Food-derived heterocyclic amines as etiologic agents in human mammary cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Meat, fat and risk of breast cancer: a case-control study from Uruguay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Chemical carcinogens and overnutrition in diet-related cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

How we should deal with unavoidable exposure of man to environmental mutagens: cooked food mutagen discovery, facts and lessons for cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

An overview of chemoprevention: current status and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

The role of peroxidase-catalyzed activation of aromatic amines in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Reaction of N-hydroxylamine and N-acetoxy derivatives of 2-amino-3-methylimidazolo[4,5-f]quinoline with DNA. Synthesis and identification of N-(deoxyguanosin-8-yl)-IQ

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Induction of the base displacement or Z conformation in DNA by N-2-acetylaminofluorene modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

DNA binding and mutation spectra of the carcinogen N-2-aminofluorene in Escherichia coli. A correlation between the conformation of the premutagenic lesion and the mutation specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Carcinogen-induced frameshift mutagenesis in repetitive sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Solution structure of the 2-amino-1- methyl-6-phenylimidazo[4,5-b]pyridine C8-deoxyguanosine adduct in duplex DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Characterization of DNA adducts formed in vitro by reaction of N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline and N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline at the C-8 and N2 atoms of guanine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

DNA adduct measurements and tumor incidence during chronic carcinogen exposure in animal models: implications for DNA adduct-based human cancer risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

DNA adducts, mutations and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Detection of DNA modifications by the 32P-postlabelling assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Human biomonitoring and the 32P-postlabeling assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Analysis and quantification of DNA adducts of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in liver of rats by liquid chromatography/electrospray tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Human exposure to carcinogenic heterocyclic amines and their mutational fingerprints in experimental animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Accelerator mass spectrometry in biomedical dosimetry: relationship between low-level exposure and covalent binding of heterocyclic amine carcinogens to DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Detection of in vivo formed DNA adducts at the part-per-billion level by capillary liquid chromatography/microelectrospray mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Quantification of the heterocyclic aromatic amine DNA adduct N-(deoxyguanosin-8-yl)-2-amino-3-methylimidazo[4,5-f]quinoline in livers of rats using capillary liquid chromatography/microelectrospray mass spectrometry: a dose-response study

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Liquid chromatography/electron capture atmospheric pressure chemical ionization/mass spectrometry: analysis of pentafluorobenzyl derivatives of biomolecules and drugs in the attomole range

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutagenic activity of heterocyclic amines in cooked foods

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Base-change analysis of revertants of the hisD3052 allele in Salmonella typhimurium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

The basis of the insensitivity of Salmonella typhimurium strain TA98/1,8-DNP6 to the mutagenic action of nitroarenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Sensitive method for the detection of mutagenic nitroarenes and aromatic amines: new derivatives of Salmonella typhimurium tester strains possessing elevated O-acetyltransferase levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutational specificity of 2-nitro-3,4-dimethylimidazo[4,5-f]quinoline in the lacI gene of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Analysis of mutational specificity induced by heterocyclic amines in the lacZ gene of Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutational and DNA binding specificity of the carcinogen 2-amino-3, 8-dimethylimidazo[4,5-f]quinoxaline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic aromatic amines by Salmonella typhimurium strain NM2009 possessing high O-acetyltransferase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Comparative genotoxic effects of the cooked-food-related mutagens Trp-P-2 and IQ in bacteria and cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Genotoxicity of compounds from cooked beef in repair-deficient CHO cells versus Salmonella mutagenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Effect of heterocyclic amines and beef extract on chromosome aberrations and sister chromatid exchanges in cultured human lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mammalian cell mutagenicity and metabolism of heterocyclic aromatic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Analysis of mutations induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutation and repair induced by the carcinogen 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in the dihydrofolate reductase gene of Chinese hamster ovary cells and conformational modeling of the dG-C8-PhIP adduct in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Identification of aprt gene mutations induced in repair-deficient and P450-expressing CHO cells by the food-related mutagen/carcinogen, PhIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutational spectra of the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine(PhIP) at the Chinese hamsters hprt locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Specific 5'-GGGA-3'-->5'-GGA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in human lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Genetic changes induced by heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

p53 gene mutation in hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

APC mutations occur early during colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Early detection of 2-amino-1-methyl-6-phenylimidazo (4,5-b)pyridine(PhIP)-induced mutations within the Apc gene of rat colon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Infrequent mutation of Ha-ras and p53 in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Agreement of mutational characteristics of heterocyclic amines in lacI of the Big Blue mouse with those in tumor related genes in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Effects of gender and species on spectra of mutation induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the lacI transgene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Preferential induction of guanine deletion at 5'-GGGA-3' in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

LacI transgenic animal study: relationships among DNA-adduct levels, mutant frequencies and cancer incidences

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Intestinal tumours induced by the food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in multiple intestinal neoplasia mice have truncation mutations as well as loss of the wild-type Apc(+) allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

In vivo mutagenicity and DNA adduct levels of heterocyclic amines in Muta mice and c-myc/lacZ double transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Transgenic mouse models in carcinogenesis research and testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Analysis of synergism in hepatocarcinogenesis based on preneoplastic foci induction by 10 heterocyclic amines in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Synergistic enhancement of small and large intestinal carcinogenesis by combined treatment of rats with five heterocyclic amines in a medium-term multi-organ bioassay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Metabolism of food-derived heterocyclic amines in nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

Protein adducts in the molecular dosimetry of chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FDMR-120005665

21 January 2018

Identifiers

DOI

10.1081/DMR-120005665

1 reference

4 August 2017

1 reference

PubMed ID

12214671