(Q34826590)

English

Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes: a parallel-group prospective cohort study in two sub-Saharan Africa populations (English)

1 reference

Europe PubMed Central

4 August 2017

Sub-Saharan Africa

0 references

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Wondwossen Amogne

6

object named as

Wondwossen Amogne

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object named as

Eyasu Makonnen

4

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object named as

Eleni Aklillu

13

0 references

Leif Bertilsson

12

object named as

Leif Bertilsson

1 reference

Europe PubMed Central

4 August 2017

Eliford Ngaimisi Kitabi

1

object named as

Eliford Ngaimisi

1 reference

Europe PubMed Central

4 August 2017

2

object named as

Abiy Habtewold

1 reference

Europe PubMed Central

4 August 2017

3

object named as

Omary Minzi

1 reference

Europe PubMed Central

4 August 2017

Wondwossen Amogne

6

object named as

Wondwossen Amogne

1 reference

Europe PubMed Central

4 August 2017

Sabina F Mugusi

5

object named as

Sabina Mugusi

1 reference

Europe PubMed Central

4 August 2017

Getachew Aderaye

10

object named as

Getachew Aderaye

1 reference

Europe PubMed Central

4 August 2017

Klaus-Dieter Riedel

8

object named as

Klaus-Dieter Riedel

1 reference

Europe PubMed Central

4 August 2017

7

object named as

Getnet Yimer

1 reference

Europe PubMed Central

4 August 2017

author name string

Mohammed Janabi

9

1 reference

Europe PubMed Central

4 August 2017

Ferdinand Mugusi

11

1 reference

Europe PubMed Central

4 August 2017

Juergen Burhenne

14

1 reference

Europe PubMed Central

4 August 2017

language of work or name

0 references

publication date

5 July 2013

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

8

1 reference

Europe PubMed Central

4 August 2017

7

1 reference

Europe PubMed Central

4 August 2017

e67946

1 reference

Europe PubMed Central

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

5 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Risk factors for mortality among HIV-positive patients with and without active tuberculosis in Dar es Salaam, Tanzania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Contribution of N-glucuronidation to efavirenz elimination in vivo in the basal and rifampin-induced metabolism of efavirenz.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Tribal ethnicity and CYP2B6 genetics in Ugandan and Zimbabwean populations in the UK: implications for efavirenz dosing in HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Laboratory reference values for healthy adults from southern Tanzania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Geography predicts neutral genetic diversity of human populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Population-based hematologic and immunologic reference values for a healthy Ugandan population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Distribution of lymphocyte subsets in healthy human immunodeficiency virus-negative adult Ethiopians from two geographic locales

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

Immunohematological reference ranges for adult Ethiopians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

8 July 2018

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

Effect of gender and race on the week 48 findings in treatment-naïve, HIV-1-infected patients enrolled in the randomized, phase III trials ECHO and THRIVE.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

Racial differences in virologic failure associated with adherence and quality of life on efavirenz-containing regimens for initial HIV therapy: results of ACTG A5095.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

Frequency of the SLCO1B1 388A>G and the 521T>C polymorphism in Tanzania genotyped by a new LightCycler®-based method

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

26 October 2018

β-defensin genomic copy number is associated with HIV load and immune reconstitution in sub-saharan Africans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

26 October 2018

Factors influencing efavirenz and nevirapine plasma concentration: effect of ethnicity, weight and co-medication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

26 October 2018

Therapeutic drug monitoring of efavirenz: trough levels cannot be estimated on the basis of earlier plasma determinations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3702506

26 October 2018

Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067946

21 January 2018

Associations between ABCB1, CYP2A6, CYP2B6, CYP2D6, and CYP3A5 alleles in relation to efavirenz and nevirapine pharmacokinetics in HIV-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/23861838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23861838

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0067946

1 reference

Europe PubMed Central

4 August 2017

2013PLoSO...867946N

0 references

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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