(Q34926820)

5 August 2017

title

Evidence for a novel mechanism of the PAK1 interaction with the Rho-GTPases Cdc42 and Rac. (English)

1 reference

5 August 2017

Adhiraj Roy

3

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author name string

Yong Jae Shin

series ordinal

1

1 reference

5 August 2017

Eun Hye Kim

series ordinal

2

1 reference

5 August 2017

Jeong-Ho Kim

series ordinal

4

1 reference

5 August 2017

language of work or name

English

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publication date

1 August 2013

1 reference

5 August 2017

1 reference

5 August 2017

volume

8

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5 August 2017

issue

8

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5 August 2017

page(s)

e71495

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Creative Commons Attribution 4.0 International

5 August 2017

copyright license

start time

1 August 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.

8 July 2018

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Activation of p21-activated kinase 1-nuclear factor kappaB signaling by Kaposi's sarcoma-associated herpes virus G protein-coupled receptor during cellular transformation

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p21-activated Kinase-1 Signaling Mediates Cyclin D1 Expression in Mammary Epithelial and Cancer Cells

8 July 2018

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p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD

8 July 2018

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8 July 2018

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8 July 2018

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Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1

8 July 2018

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Conformational switch and role of phosphorylation in PAK activation

8 July 2018

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The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

8 July 2018

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8 July 2018

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8 July 2018

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Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

8 July 2018

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8 July 2018

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Structure of Cdc42 bound to the GTPase binding domain of PAK

8 July 2018

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Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1

8 July 2018

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Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

8 July 2018

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Genetic evidence for Pak1 autoinhibition and its release by Cdc42.

8 July 2018

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A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

8 July 2018

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Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation

8 July 2018

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Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731272

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731272

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731272

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731272

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731272

Phosphorylation of a Ras-related GTP-binding protein, Rap-1b, by a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase Gr.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731272

A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0071495

Unbalanced expression of CK2 kinase subunits is sufficient to drive epithelial-to-mesenchymal transition by Snail1 induction.

21 January 2018

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Amphotericin B induced ventricular arrhythmia and its relation to central venous line.

26 October 2018

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A case report on the treatment of intractable anal pain from metastatic carcinoma of the cervix.

26 October 2018

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The sinister significance of dysphagia

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Prospective randomised open-label comparison of danaparoid with dextran 70 in the treatment of heparin-induced thrombocytopaenia with thrombosis: a clinical outcome study

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10.1371/JOURNAL.PONE.0071495

Identifiers

DOI

1 reference

5 August 2017

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1 reference

5 August 2017

1 reference