(Q34946464)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

SIRT1 deficiency in microglia contributes to cognitive decline in aging and neurodegeneration via epigenetic regulation of IL-1β (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Faten Sayed

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Michael E Ward

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Michael E Ward

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Seo-Hyun Cho

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Fuying Gao

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Thi A Nguyen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Grietje Krabbe

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Peter Dongmin Sohn

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Iris Lo

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Sakura Minami

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Nino Devidze

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Yungui Zhou

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Giovanni Coppola

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Li Gan

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

language of work or name

English

0 references

publication date

1 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

807-818

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

27 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4293425/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4293425

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Identification of a unique TGF-β-dependent molecular and functional signature in microglia

8 July 2018

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The microglial sensome revealed by direct RNA sequencing

8 July 2018

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A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model

8 July 2018

1 reference

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Metabolic and neuropsychiatric effects of calorie restriction and sirtuins

8 July 2018

1 reference

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Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

8 July 2018

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NF-κB inhibition delays DNA damage-induced senescence and aging in mice

8 July 2018

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

8 July 2018

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SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

8 July 2018

1 reference

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Inflammation, DNA methylation and colitis-associated cancer

8 July 2018

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8 July 2018

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Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model

8 July 2018

1 reference

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Microglia and memory: modulation by early-life infection

8 July 2018

1 reference

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SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Protective effects and mechanisms of sirtuins in the nervous system

8 July 2018

1 reference

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CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.

8 July 2018

1 reference

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Activation of nuclear factor-kappa B signalling promotes cellular senescence

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

8 July 2018

1 reference

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Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress.

8 July 2018

1 reference

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The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction

8 July 2018

1 reference

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Mechanisms underlying inflammation in neurodegeneration

8 July 2018

1 reference

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Microglia in neurodegenerative disease

8 July 2018

1 reference

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DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes

8 July 2018

1 reference

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Immune activation in brain aging and neurodegeneration: too much or too little?

8 July 2018

1 reference

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Microglial physiology: unique stimuli, specialized responses

8 July 2018

1 reference

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How does SIRT1 affect metabolism, senescence and cancer?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Functional organization of the transcriptome in human brain

8 July 2018

1 reference

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The IL-33/ST2 pathway: therapeutic target and novel biomarker

8 July 2018

1 reference

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Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

8 July 2018

1 reference

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Paths of convergence: sirtuins in aging and neurodegeneration

8 July 2018

1 reference

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The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

8 July 2018

1 reference

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SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.

8 July 2018

1 reference

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Sirtuins in mammals: insights into their biological function

8 July 2018

1 reference

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

8 July 2018

1 reference

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Microglia derived from aging mice exhibit an altered inflammatory profile.

8 July 2018

1 reference

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A general framework for weighted gene co-expression network analysis

8 July 2018

1 reference

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

8 July 2018

1 reference

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Gene regulation and DNA damage in the ageing human brain

8 July 2018

1 reference

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

The immune system and memory consolidation: a role for the cytokine IL-1beta.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Altered antigen expression of microglia in the aged rodent CNS.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Effects of ageing on microglia in the normal rat brain: immunohistochemical observations.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Priming of microglia in a DNA-repair deficient model of accelerated aging.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Designing, performing, and interpreting a microarray-based gene expression study

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Evidence that aging and amyloid promote microglial cell senescence.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Innate immune receptor expression in normal brain aging.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Effects of axotomy on telomere length, telomerase activity, and protein in activated microglia.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

Increased interleukin-6 expression by microglia from brain of aged mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293425

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25589773

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.2939-14.2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25589773%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

25589773

1 reference