(Q36164195)

English

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study (English)

1 reference

Europe PubMed Central

12 August 2017

author name string

David H Cribbs

1

1 reference

Europe PubMed Central

12 August 2017

Nicole C Berchtold

2

1 reference

Europe PubMed Central

12 August 2017

Victoria Perreau

3

1 reference

Europe PubMed Central

12 August 2017

Paul D Coleman

4

1 reference

Europe PubMed Central

12 August 2017

Joseph Rogers

5

1 reference

Europe PubMed Central

12 August 2017

Andrea J Tenner

6

1 reference

Europe PubMed Central

12 August 2017

Carl W Cotman

7

1 reference

Europe PubMed Central

12 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

23 July 2012

1 reference

Europe PubMed Central

12 August 2017

Journal of Neuroinflammation

1 reference

Europe PubMed Central

12 August 2017

9

1 reference

Europe PubMed Central

12 August 2017

179

1 reference

Europe PubMed Central

12 August 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-9-179

0 references

CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity

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Complement activation as a biomarker for Alzheimer's disease

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Extended results of the Alzheimer's disease anti-inflammatory prevention trial

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Toll-like receptors are key players in neurodegeneration

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The early involvement of the innate immunity in the pathogenesis of late-onset Alzheimer's disease: neuropathological, epidemiological and genetic evidence.

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Reimagining Alzheimer's disease--an age-based hypothesis

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Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy

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Beclin 1 complex in autophagy and Alzheimer disease

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Protein homeostasis and aging in neurodegeneration

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S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis.

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Regulation of amyloid precursor protein processing by the Beclin 1 complex

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Age- and gender-related differences in the cortical anatomical network

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Immune activation in brain aging and neurodegeneration: too much or too little?

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Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease

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Regulation of innate immune responses in the brain

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Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort.

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Propagation of tau misfolding from the outside to the inside of a cell.

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Selective targeting of perivascular macrophages for clearance of beta-amyloid in cerebral amyloid angiopathy.

1 reference

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Gene expression changes in the course of normal brain aging are sexually dimorphic

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Endogenous signals initiating inflammation in the injured nervous system

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

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Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease

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Toll-like receptors 2 and 4 mediate Abeta(1-42) activation of the innate immune response in a human monocytic cell line

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Role of the toll-like receptor 4 in neuroinflammation in Alzheimer's disease.

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Activation of Toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide.

1 reference

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Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

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Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice

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Toll-like receptors and innate immunity

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Inflammation and Alzheimer's disease

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Inflammation and Alzheimer's disease pathogenesis

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Microglia in degenerative neurological disease.

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Complement activation by beta-amyloid in Alzheimer disease

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Chronic inflammation in Alzheimer's disease offers therapeutic opportunities.

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2 July 2018

Microglia, amyloid and dementia in alzheimer disease. A correlative study.

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2 July 2018

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2 July 2018

Localization and cell association of C1q in Alzheimer's disease brain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

2 July 2018

Soothing the inflamed brain: effect of non-steroidal anti-inflammatory drugs on Alzheimer's disease pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Sex dimorphism in gray/white matter volume and diffusion tensor during normal aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Early-stage inflammation and experimental therapy in transgenic models of the Alzheimer-like amyloid pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

A longitudinal study of gray matter volume decline with age and modifying factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

The inflammatory hypothesis of Alzheimer disease: dead or alive?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Peripheral clearance of amyloid beta peptide by complement C3-dependent adherence to erythrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Microglia kill amyloid-beta1-42 damaged neurons by a CD14-dependent process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Innate immune reaction in response to seizures: implications for the neuropathology associated with epilepsy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

The LPS receptor (CD14) links innate immunity with Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Beta-amyloid fibrils activate the C1 complex of complement under physiological conditions: evidence for a binding site for A beta on the C1q globular regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Neuroinflammation-induced acceleration of amyloid deposition in the APPV717F transgenic mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

A revised view of the central nervous system microenvironment and major histocompatibility complex class II antigen presentation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Importance of immunological and inflammatory processes in the pathogenesis and therapy of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Molecular and cellular characterization of the membrane attack complex, C5b-9, in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3419089

23 September 2018

NSAIDs and incident Alzheimer’s disease. the Rotterdam study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NLR functions beyond pathogen recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune reactive cells in senile plaques and cognitive decline in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahippocampal LPS injections reduce Abeta load in APP+PS1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemoglobin scavenger receptor CD163 mediates interleukin-10 release and heme oxygenase-1 synthesis: antiinflammatory monocyte-macrophage responses in vitro, in resolving skin blisters in vivo, and after cardiopulmonary bypass surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/22824372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-2094-9-179

1 reference

Europe PubMed Central

12 August 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

ResearchGate publication ID

0 references

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