(Q34993939)

5 August 2017

1 reference

title

Chloride channels in the kidney: lessons learned from knockout animals (English)

1 reference

5 August 2017

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1

Olivier Devuyst

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William B Guggino

series ordinal

2

object named as

William B Guggino

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5 August 2017

language of work or name

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1 December 2002

1 reference

American Journal of Physiology - Renal Physiology

5 August 2017

published in

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5 August 2017

volume

283

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5 August 2017

issue

6

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5 August 2017

page(s)

F1176-91

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Impaired solute accumulation in inner medulla of Clcnk1-/- mice kidney

5 August 2017

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21 January 2018

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Chloride channels in the apical membrane of normal and cystic fibrosis airway and intestinal epithelia

21 January 2018

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An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomes

21 January 2018

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Protein kinase A regulates chloride conductance in endocytic vesicles from proximal tubule

21 January 2018

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Defective acidification of intracellular organelles in cystic fibrosis

21 January 2018

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Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities

21 January 2018

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Properties of chloride-conductive pathways in rat kidney cortical and outer-medulla brush-border membranes--inhibition by anti-(cystic fibrosis transmembrane regulator) mAbs.

21 January 2018

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Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure

21 January 2018

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Male germ cells and photoreceptors, both dependent on close cell-cell interactions, degenerate upon ClC-2 Cl(-) channel disruption

21 January 2018

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Regulation of plasma membrane recycling by CFTR.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Regulated endocytosis in a chloride secretory epithelial cell line

21 January 2018

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Immunolocalization of ion transport proteins in human autosomal dominant polycystic kidney epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

The genetics and physiology of polycystic kidney disease

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Aberrant CFTR-dependent HCO3- transport in mutations associated with cystic fibrosis

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule

21 January 2018

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Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Albers-Schönberg disease (autosomal dominant osteopetrosis, type II) results from mutations in the ClCN7 chloride channel gene

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Generation and characterization of a delta F508 cystic fibrosis mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Immunocytochemical localization of the cystic fibrosis gene product CFTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Developmental regulation of CFTR expression during human nephrogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Intra-renal and subcellular distribution of the human chloride channel, CLC-5, reveals a pathophysiological basis for Dent's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Regulation of collecting duct water channel expression by vasopressin in Brattleboro rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cystic fibrosis in the mouse by targeted insertional mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Pore stoichiometry of a voltage-gated chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Pore-forming segments in voltage-gated chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Mutational analysis demonstrates that ClC-4 and ClC-5 directly mediate plasma membrane currents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Ca(2+)-activated Cl(-) channels: a newly emerging anion transport family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Evidence against the acidification hypothesis in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Ion transport mechanisms in thick ascending limb of Henle's loop of mammalian nephron

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Ion transport across the jejunum in normal and cystic fibrosis mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Pathophysiology of gene-targeted mouse models for cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Hyperabsorption of Na+ and raised Ca(2+)-mediated Cl- secretion in nasal epithelia of CF mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

ClC-5, the chloride channel mutated in Dent's disease, colocalizes with the proton pump in endocytotically active kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Molecular basis of polycystic kidney disease: PKD1, PKD2 and PKHD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Megalin antagonizes activation of the parathyroid hormone receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Toward a comprehensive molecular model of active calcium reabsorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Embryonic epithelial membrane transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CFTR mRNA and its truncated splice variant (TRN-CFTR) are differentially expressed during collecting duct ontogeny.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Anion secretion by the inner medullary collecting duct. Evidence for involvement of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Functional characterization of renal chloride channel, CLCN5, mutations associated with Dent'sJapan disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

cAMP and genistein stimulate HCO3- conductance through CFTR in human airway epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Sodium chloride, urea, and water transport in the thin ascending limb of Henle. Generation of osmotic gradients by passive diffusion of solutes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Function of thin loops of Henle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Molecular structure and physiological function of chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

DeltaF508 CFTR protein expression in tissues from patients with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Microscopic nephrocalcinosis in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Two highly homologous members of the ClC chloride channel family in both rat and human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Regulation of aquaporin-2 water channel trafficking by vasopressin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Countercurrent multiplication system without active transport in inner medulla

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Effects of anion transport inhibitors and ion substitution on Cl- transport in TAL of Henle's loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Functional significance of cell volume regulatory mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cystic fibrosis transmembrane conductance regulator regulates luminal Cl-/HCO3- exchange in mouse submandibular and pancreatic ducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

cAMP stimulates CFTR-like Cl- channels and inhibits amiloride-sensitive Na+ channels in mouse CCD cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Characterisation of renal chloride channel, CLCN5, mutations in hypercalciuric nephrolithiasis (kidney stones) disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

A common molecular basis for three inherited kidney stone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Idiopathic low molecular weight proteinuria associated with hypercalciuric nephrocalcinosis in Japanese children is due to mutations of the renal chloride channel (CLCN5)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Two physically distinct pores in the dimeric ClC-0 chloride channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Diet-dependent hypercalciuria in transgenic mice with reduced CLC5 chloride channel expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cl- absorption across the thick ascending limb is not altered in cystic fibrosis mice. A role for a pseudo-CFTR Cl- channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Acidification of the endocytic and exocytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

The chloride channel ClC-4 co-localizes with cystic fibrosis transmembrane conductance regulator and may mediate chloride flux across the apical membrane of intestinal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Both the wild type and a functional isoform of CFTR are expressed in kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Arginine vasopressin regulates CFTR and ClC-2 mRNA expression in rat kidney cortex and medulla

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Nephrogenic diabetes insipidus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Gestational and tissue-specific regulation of C1C-2 chloride channel expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CIC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Modifier genes in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

The swelling-activated chloride channel ClC-2, the chloride channel ClC-3, and ClC-5, a chloride channel mutated in kidney stone disease, are expressed in distinct subpopulations of renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Aldosterone and high-NaCl diet modulate ClC-2 chloride channel gene expression in rat kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

ClC-5 Cl- -channel disruption impairs endocytosis in a mouse model for Dent's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Analysis of organ physiology in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Production of a severe cystic fibrosis mutation in mice by gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Protein kinase A dependent membrane protein phosphorylation and chloride conductance in endosomal vesicles from kidney cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Interaction of chloride and bicarbonate transport across the basolateral membrane of rabbit proximal straight tubule. Evidence for sodium coupled chloride/bicarbonate exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

X-linked hypercalciuric nephrolithiasis: clinical syndromes and chloride channel mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Genetic disorders of renal electrolyte transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Single chloride channels in endosomal vesicle preparations from rat kidney cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Transmembrane topology of a CLC chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CFTR is a conductance regulator as well as a chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Evidence against defective trans-Golgi acidification in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Structure and function of the CFTR chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Heterogeneity in ATP-dependent acidification in endocytic vesicles from kidney proximal tubule. Measurement of pH in individual endocytic vesicles in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

The activity of the epithelial sodium channel is regulated by clathrin-mediated endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

An animal model for cystic fibrosis made by gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cloning and functional expression of rat CLC-5, a chloride channel related to kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Decreased renal clearance of sodium in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cellular and molecular physiology of volume-sensitive anion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CFTR as a cAMP-dependent regulator of sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Uncompensated polyuria in a mouse model of Bartter's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Chloride currents activated by calcitonin and cAMP in primary cultures of rabbit distal convoluted tubule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

A chloride channel widely expressed in epithelial and non-epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

In vivo role of CLC chloride channels in the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Localization and functional characterization of rat kidney-specific chloride channel, ClC-K1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Localization and induction by dehydration of ClC-K chloride channels in the rat kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

CFTR mediates electrogenic chloride secretion in mouse inner medullary collecting duct (mIMCD-K2) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Molecular cloning and expression of a cyclic AMP-activated chloride conductance regulator: a novel ATP-binding cassette transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

A gene from the Xp22.3 region shares homology with voltage-gated chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Rapid gating and anion permeability of an intracellular aquaporin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Aquaporin-6: An intracellular vesicle water channel protein in renal epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Evidence for conductive Cl- pathways across the cell membranes of the thin ascending limb of Henle's loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Role of ClC-5 in the pathogenesis of hypercalciuria: recent insights from transgenic mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

A mouse model for the delta F508 allele of cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Cl- channels in basolateral renal medullary vesicles. X. Cloning of a Cl- channel from rabbit outer medulla

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Tissue distribution and subcellular localization of the ClC-5 chloride channel in rat intestinal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

Surviving a knockout blow

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00184.2002

10.1152/AJPRENAL.00184.2002

21 January 2018

Identifiers

DOI

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1 reference