(Q35006343)

English

Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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pancreatic cancer

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based on heuristic

inferred from title

object named as

Xueji Zhang

7

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ORCID Public Data File 2021

author name string

Feng Wang

1

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Europe PubMed Central

PubMed publication ID

5 August 2017

Qi Wang

2

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Europe PubMed Central

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5 August 2017

Zhi-Wei Zhou

3

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Europe PubMed Central

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5 August 2017

Song-Ning Yu

4

1 reference

Europe PubMed Central

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5 August 2017

Shu-Ting Pan

5

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Europe PubMed Central

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5 August 2017

Zhi-Xu He

6

1 reference

Europe PubMed Central

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5 August 2017

Dong Wang

8

1 reference

Europe PubMed Central

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5 August 2017

Yin-Xue Yang

9

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Europe PubMed Central

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5 August 2017

Tianxing Yang

10

1 reference

Europe PubMed Central

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5 August 2017

Tao Sun

11

1 reference

Europe PubMed Central

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5 August 2017

Min Li

12

1 reference

Europe PubMed Central

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5 August 2017

Jia-Xuan Qiu

13

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Europe PubMed Central

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5 August 2017

Shu-Feng Zhou

14

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Europe PubMed Central

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5 August 2017

language of work or name

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publication date

17 January 2015

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Europe PubMed Central

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5 August 2017

Drug Design, Development and Therapy

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Europe PubMed Central

PubMed publication ID

5 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

537-560

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Europe PubMed Central

PubMed publication ID

5 August 2017

copyright license

Creative Commons Attribution-NonCommercial 3.0 Unported

1 January 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Molecular mechanisms of epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Role of autophagy in apoptotic regulation by Akt in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Cancer statistics, 2014

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Cancer preventive efficacy of marine carotenoid fucoxanthin: cell cycle arrest and apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Mitogen-activated protein kinases in innate immunity

1 reference

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8 July 2018

The kinase triad, AMPK, mTORC1 and ULK1, maintains energy and nutrient homoeostasis

1 reference

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8 July 2018

Sirtuins' modulation of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Multilayer control of the EMT master regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Another fork in the road--life or death decisions by the tumour suppressor p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Development of PI3K inhibitors: lessons learned from early clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Report of incidence and mortality in China cancer registries, 2009.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Targeting cell cycle regulation in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Sirtuin deacylases: a molecular link between metabolism and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

p21WAF1 and tumourigenesis: 20 years after

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Emerging cell-cycle inhibitors for pancreatic cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Perspectives on medicinal properties of plumbagin and its analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Autophagic lysosome reformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Cell cycle regulation by the intrinsically disordered proteins p21 and p27.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Autophagy in pancreatic cancer pathogenesis and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

The mitochondrial pathways of apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin, a plant derived natural agent inhibits the growth of pancreatic cancer cells in in vitro and in vivo via targeting EGFR, Stat3 and NF-κB signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Cell death by autophagy: facts and apparent artefacts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin treatment leads to apoptosis in human K562 leukemia cells through increased ROS and elevated TRAIL receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Epithelial-to-mesenchymal transition in prostate cancer: paradigm or puzzle?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Apoptosis inducing effect of plumbagin on colonic cancer cells depends on expression of COX-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

A critical role for autophagy in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Autophagy in pancreatic cancer: an emerging mechanism of cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin activates ERK1/2 and Akt via superoxide, Src and PI3-kinase in 3T3-L1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Epithelial-mesenchymal transition: from molecular mechanisms, redox regulation to implications in human health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin inhibits TPA-induced MMP-2 and u-PA expressions by reducing binding activities of NF-kappaB and AP-1 via ERK signaling pathway in A549 human lung cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin induces ROS-mediated apoptosis in human promyelocytic leukemia cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin induces cell death through a copper-redox cycle mechanism in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Apoptosis: controlled demolition at the cellular level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Current diagnosis and treatment of pancreatic cancer in China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Nuclear apoptosis detection by flow cytometry: influence of endogenous endonucleases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

The phosphoinositide 3-kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Autophagy as a regulated pathway of cellular degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

8 July 2018

Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

26 October 2018

Autophagy proteins in prostate cancer: relation with anaerobic metabolism and Gleason score.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4304578

26 October 2018

The cell cycle and cancer

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12 December 2020

based on heuristic

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Cancer statistics: current diagnosis and treatment of pancreatic cancer in Shanghai, China

1 reference

https://pubmed.ncbi.nlm.nih.gov/25632222

12 December 2020

based on heuristic

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Autophagy, p53, and Pancreatic Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25632222

12 December 2020

based on heuristic

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Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25632222

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2147/DDDT.S73689

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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