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Similarities between the Hedgehog and Wnt signaling pathways
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Similarities between the Hedgehog and Wnt signaling pathways
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
author name string
Daniel Kalderon
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
publication date
1 November 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
published in
Trends in Cell Biology
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
volume
12
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
issue
11
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
page(s)
523-531
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
cites work
New aspects of Wnt signaling pathways in higher vertebrates
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Crossref
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Hedgehog signaling in animal development: paradigms and principles
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The Hedgehog and Wnt signalling pathways in cancer
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Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway
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Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1.
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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The ballet of morphogenesis: unveiling the hidden choreographers
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7 January 2021
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The low-density lipoprotein receptor gene family: a cellular Swiss army knife?
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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arrow encodes an LDL-receptor-related protein essential for Wingless signalling
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Megalin functions as an endocytic sonic hedgehog receptor
1 reference
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Planar signaling and morphogenesis in Drosophila
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7 January 2021
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Regulation of Frizzled by fat-like cadherins during planar polarity signaling in the Drosophila compound eye.
1 reference
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7 January 2021
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Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Patched acts catalytically to suppress the activity of Smoothened
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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The sterol-sensing domain: multiple families, a unique role?
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Sonic hedgehog induces the segregation of patched and smoothened in endosomes
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Activation of a frizzled-2/beta-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Galphao and Galphat
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7 January 2021
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G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Dishevelled: at the crossroads of divergent intracellular signaling pathways
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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The dishevelled protein is modified by wingless signaling in Drosophila
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis.
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Interaction of axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription.
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Smoothened activates Galphai-mediated signaling in frog melanophores
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Crossref
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Casein kinase I transduces Wnt signals
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Crossref
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
based on heuristic
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PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
based on heuristic
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Wnt signaling controls the phosphorylation status of beta-catenin.
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Regulation of the protein kinase activity of Shaggy(Zeste-white3) by components of the wingless pathway in Drosophila cells and embryos
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
based on heuristic
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Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Identification of a tetrameric hedgehog signaling complex
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Genetic dissection of the Drosophila Cubitus interruptus signaling complex
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Drosophila Roc1a encodes a RING-H2 protein with a unique function in processing the Hh signal transducer Ci by the SCF E3 ubiquitin ligase
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Mechanisms of ubiquitin-mediated, limited processing of the NF-kappaB1 precursor protein p105.
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Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Adhesion signaling: how beta-catenin interacts with its partners
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The subcellular destinations of APC proteins
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7 January 2021
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Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
The APC tumour suppressor has a nuclear export function.
1 reference
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https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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Getting legless with a Pygopus.
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7 January 2021
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Suppressor of fused negatively regulates beta-catenin signaling
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0962-8924%2802%2902388-7
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7 January 2021
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Identifiers
DOI
10.1016/S0962-8924(02)02388-7
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
PubMed ID
12446114
1 reference
stated in
Europe PubMed Central
PubMed ID
12446114
retrieved
5 August 2017
ResearchGate publication ID
11023084
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