(Q35009728)

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Prion protein misfolding

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scholarly article

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Europe PubMed Central

5 August 2017

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21 December 2019

Prion protein misfolding (English)

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Europe PubMed Central

5 August 2017

prion protein family

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1 reference

21 December 2019

Winfried Hinrichs

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W Hinrichs

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author name string

L Kupfer

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Europe PubMed Central

5 August 2017

M H Groschup

3

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Europe PubMed Central

5 August 2017

publication date

1 September 2009

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Europe PubMed Central

5 August 2017

21 December 2019

Current Molecular Medicine

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Europe PubMed Central

5 August 2017

21 December 2019

9

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Europe PubMed Central

5 August 2017

7

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Europe PubMed Central

5 August 2017

826-835

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Europe PubMed Central

5 August 2017

copyright license

Creative Commons Attribution 2.5 Generic

1 reference

Europe PubMed Central

21 December 2019

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

The amphiphilic properties of spider silks are important for spinning.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Chronic wasting disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

The possible role of protein X, a putative auxiliary factor in pathological prion replication, in regulating a physiological endoproteolytic cleavage of cellular prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

The charge structure of helix 1 in the prion protein regulates conversion to pathogenic PrPSc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Synthetic prions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Interaction of metals with prion protein: possible role of divalent cations in the pathogenesis of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Inducible proteopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Structural instability of the prion protein upon M205S/R mutations revealed by molecular dynamics simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Analysis of prion strains by PrPSc profiling in sporadic Creutzfeldt-Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

The most infectious prion protein particles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

The highways and byways of prion protein trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Prion protein NMR structures of chickens, turtles, and frogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Prion protein NMR structures of elk and of mouse/elk hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

NMR structure of the bovine prion protein isolated from healthy calf brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Comparative computational analysis of prion proteins reveals two fragments with unusual structural properties and a pattern of increase in hydrophobicity associated with disease-promoting mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Therapeutic approaches in treating Creutzfeldt-Jakob disease - what does the future hold?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Evidence for assembly of prions with left-handed beta-helices into trimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Preferential Cu2+ coordination by His96 and His111 induces beta-sheet formation in the unstructured amyloidogenic region of the prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Protein folding and misfolding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Emerging therapeutic agents for transmissible spongiform encephalopathies: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Introduction to the transmissible spongiform encephalopathies or prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Therapeutic approaches to prion diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Contribution of two conserved glycine residues to fibrillogenesis of the 106-126 prion protein fragment. Evidence that a soluble variant of the 106-126 peptide is neurotoxic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Multiple amino acid residues within the rabbit prion protein inhibit formation of its abnormal isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Glycosylation and prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Infective proteins: the prion puzzle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Prion diseases: pathogenesis and public health concerns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Crystal structure of the human prion protein reveals a mechanism for oligomerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Prion diseases of humans and animals: their causes and molecular basis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Amyloid fibrils from muscle myoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Two different neurodegenerative diseases caused by proteins with similar structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Analyzing the influence of PrP primary structure on prion pathogenesis in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

PrP(Sc) typing by N-terminal sequencing and mass spectrometry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Self-assembly of recombinant prion protein of 106 residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Nature disfavors sequences of alternating polar and non-polar amino acids: implications for amyloidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Predicting conformational switches in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Copper binding to the prion protein: structural implications of four identical cooperative binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Prion protein NMR structure and familial human spongiform encephalopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Selective neuronal targeting in prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Chaperone-supervised conversion of prion protein to its protease-resistant form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Probing the dynamics of prion diseases with amphotericin B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Solid-state NMR studies of the prion protein H1 fragment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

NMR structure of the mouse prion protein domain PrP(121-231)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Novel proteinaceous infectious particles cause scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Sulfated glycosaminoglycans in amyloid plaques of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Sulfated glycosaminoglycans: a common constituent of all amyloids?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Aminoacid polymorphism in human prion protein and age at death in inherited prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Evidence for synthesis of scrapie prion proteins in the endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

8 July 2018

Reduced susceptibility to bovine spongiform encephalopathy prions in transgenic mice expressing a bovine PrP with five octapeptide repeats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Spider silk and amyloid fibrils: a structural comparison

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Amino acid sequence and prion strain specific effects on the in vitro and in vivo convertibility of ovine/murine and bovine/murine prion protein chimeras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Putative aggregation initiation sites in prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Increased incidence of genetic human prion disease in Hungary.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Amyloid fibril formation can proceed from different conformations of a partially unfolded protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

The N-terminal cleavage site of PrPSc from BSE differs from that of PrPSc from scrapie

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Polymerization of proteins into amyloid protofibrils shares common critical oligomeric states but differs in the mechanisms of their formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Cellular prion protein acquires resistance to proteolytic degradation following copper ion binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant: implications for disease susceptibility to Creutzfeldt-Jakob disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Helix H1 of the prion protein is rather stable against environmental perturbations: molecular dynamics of mutation and deletion variants of PrP(90-231).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

The crystal structure of the globular domain of sheep prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Flexible N-terminal region of prion protein influences conformation of protease-resistant prion protein isoforms associated with cross-species scrapie infection in vivo and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Autocatalytic conversion of recombinant prion proteins displays a species barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

The role of helix 1 aspartates and salt bridges in the stability and conversion of prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Amyloidogenic unfolding intermediates differentiate sheep prion protein variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Molecular basis of scrapie strain glycoform variation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Pathway complexity of prion protein assembly into amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Prion glycoprotein: structure, dynamics, and roles for the sugars

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Neurotoxicity of a prion protein fragment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3330701

26 October 2018

The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation reduces the fibrillation but not the neurotoxicity of the prion peptide PrP106-126

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo cytotoxicity of the prion protein fragment 106-126

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solution conformations and aggregational properties of synthetic amyloid beta-peptides of Alzheimer's disease. Analysis of circular dichroism spectra

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peptides and proteins in neurodegenerative disease: helix propensity of a polypeptide containing helix 1 of the mouse prion protein studied by NMR and CD spectroscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Helix Capping in the Stability of the Mouse Prion (180–213) Segment: Investigation through Molecular Dynamics Simulations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strain typing of German transmissible spongiform encephalopathies field cases in small ruminants by biochemical methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prion protein helix1 promotes aggregation but is not converted into beta-sheet

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tandem repeat-like domain of "similar to prion protein" (StPrP) of Japanese pufferfish binds Cu(II) as effectively as the mammalian protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic and strain-specific effects of bovine spongiform encephalopathy and scrapie prions in the cell-free conversion of recombinant prion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleic acids in prion preparations: unspecific background or essential component?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19860662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2174/156652409789105543

1 reference

Europe PubMed Central

5 August 2017

release_5xzqfzbvfzgdvejifhigsn72oq

1 reference

https://api.fatcat.wiki/v0/release/5xzqfzbvfzgdvejifhigsn72oq

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

ResearchGate publication ID

0 references

Sitelinks

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