(Q35025959)

5 August 2017

title

Nuclease-mediated gene editing by homologous recombination of the human globin locus (English)

1 reference

5 August 2017

Richard A Voit

1

1 reference

5 August 2017

Ayal Hendel

series ordinal

2

1 reference

5 August 2017

Shondra M Pruett-Miller

series ordinal

3

1 reference

5 August 2017

Matthew H Porteus

series ordinal

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

23 October 2013

1 reference

5 August 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

published in

Nucleic Acids Research

1 reference

5 August 2017

volume

42

1 reference

5 August 2017

issue

2

1 reference

5 August 2017

page(s)

1365-1378

1 reference

Creative Commons Attribution 3.0 Unported

5 August 2017

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Generation of an HIV resistant T-cell line by targeted "stacking" of restriction factors

8 July 2018

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FLASH assembly of TALENs for high-throughput genome editing

8 July 2018

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cAMP response element-binding protein 1 is required for hydroxyurea-mediated induction of γ-globin expression in K562 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Generation of a genomic reporter assay system for analysis of γ- and β-globin gene regulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Structural Basis for Sequence-Specific Recognition of DNA by TAL Effectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Genetic engineering of human pluripotent cells using TALE nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Targeted genome editing across species using ZFNs and TALENs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

A TALE nuclease architecture for efficient genome editing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Update on fetal hemoglobin gene regulation in hemoglobinopathies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

A rapid and general assay for monitoring endogenous gene modification

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Targeting DNA double-strand breaks with TAL effector nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Breaking the code of DNA binding specificity of TAL-type III effectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

A simple cipher governs DNA recognition by TAL effectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Real-time DNA sequencing from single polymerase molecules

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Site-specific, Rep-mediated integration of the intact beta-globin locus in the human erythroleukaemic cell line K562.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Comparison of zinc finger nucleases for use in gene targeting in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Mammalian gene targeting with designed zinc finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

The molecular mechanism of fetal hemoglobin reactivation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Pharmacologic modulation of fetal hemoglobin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Accumulation of gamma-globin mRNA and induction of erythroid differentiation after treatment of human leukaemic K562 cells with tallimustine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

In vitro effect on human leukemic K562 cells of co-administration of liposome-associated retinoids and cytosine arabinoside (Ara-C).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Human leukemia K562 cells: induction to erythroid differentiation by guanine, guanosine and guanine nucleotides.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Inhibitors of cell division reversibly modify hemoglobin concentration in human erythroleukemia K562 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Comparison of intron-dependent and intron-independent gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Design of retrovirus vectors for transfer and expression of the human beta-globin gene.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Cucurbitacin D induces fetal hemoglobin synthesis in K562 cells and human hematopoietic progenitors through activation of p38 pathway and stabilization of the γ-globin mRNA.

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Heritable gene targeting in zebrafish using customized TALENs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Knockout rats generated by embryo microinjection of TALENs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Optimized TAL effector nucleases (TALENs) for use in treatment of sickle cell disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Zileuton induces hemoglobin F synthesis in erythroid progenitors: role of the L-arginine-nitric oxide signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKT947

Seamless correction of the sickle cell disease mutation of the HBB gene in human induced pluripotent stem cells using TALENs

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3902937

Hemin-induced acceleration of hemoglobin production in immature cultured erythroid cells: preferential enhancement of fetal hemoglobin

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24157834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKT947

1 reference

5 August 2017

1 reference

5 August 2017

1 reference