(Q35051305)

6 August 2017

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title

Neuronal survival in the balance: are endoplasmic reticulum membrane proteins the fulcrum? (English)

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ORCID Public Data File 2021

6 August 2017

main subject

endoplasmic reticulum

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author name string

Glazner GW

series ordinal

1

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6 August 2017

Fernyhough P

series ordinal

2

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6 August 2017

publication date

1 November 2002

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6 August 2017

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6 August 2017

volume

32

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6 August 2017

issue

5-6

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6 August 2017

page(s)

421-433

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Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity.

6 August 2017

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Neuronal calcium stores.

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7 January 2021

The endoplasmic reticulum: one continuous or several separate Ca(2+) stores?

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7 January 2021

Effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-activated Ca2+ signaling in mouse lacrimal acinar cells

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7 January 2021

Calcium-induced calcium release in neurones

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7 January 2021

The role of calcium in apoptosis

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7 January 2021

Apoptosis in neurodegenerative disorders

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7 January 2021

Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.

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7 January 2021

Cellular defenses against excitotoxic insults

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7 January 2021

A supramicromolar elevation of intracellular free calcium ([Ca(2+)](i)) is consistently required to induce the execution phase of apoptosis

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7 January 2021

Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

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7 January 2021

Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway.

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7 January 2021

Maintenance of calcium homeostasis in the endoplasmic reticulum by Bcl-2

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7 January 2021

Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells

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7 January 2021

The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation

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7 January 2021

Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity

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7 January 2021

Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain?

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7 January 2021

Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states

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7 January 2021

Diabetes-induced alterations in calcium homeostasis in sensory neurones of streptozotocin-diabetic rats are restricted to lumbar ganglia and are prevented by neurotrophin-3.

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7 January 2021

Calcium and neuronal ageing

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7 January 2021

Diabetes-induced changes in calcium homeostasis and the effects of calcium channel blockers in rat and mice nociceptive neurons

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7 January 2021

Calcium - a life and death signal

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7 January 2021

T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis

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7 January 2021

Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor

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7 January 2021

Apoptosis driven by IP(3)-linked mitochondrial calcium signals

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7 January 2021

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

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7 January 2021

HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity

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7 January 2021

Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death.

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7 January 2021

Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells

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7 January 2021

The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals

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7 January 2021

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

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7 January 2021

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

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7 January 2021

Regulated translation initiation controls stress-induced gene expression in mammalian cells

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7 January 2021

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

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7 January 2021

Perk is essential for translational regulation and cell survival during the unfolded protein response

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7 January 2021

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

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7 January 2021

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

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7 January 2021

Molecular pathways of protein synthesis inhibition during brain reperfusion: implications for neuronal survival or death

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7 January 2021

Neuroprotective nitric oxide synthase inhibitor reduces intracellular calcium accumulation following transient global ischemia in the gerbil

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7 January 2021

Cell death, calcium mobilization, and immunostaining for phosphorylated eukaryotic initiation factor 2-alpha (eIF2alpha) in neuronally differentiated NB-104 cells: arachidonate and radical-mediated injury mechanisms

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7 January 2021

Effect of nitric oxide on endoplasmic reticulum calcium homeostasis, protein synthesis and energy metabolism

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7 January 2021

Interaction of ATF6 and serum response factor

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7 January 2021

The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis

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7 January 2021

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Calcium-sensitive transcriptional activation of the proximal CCAAT regulatory element of the grp78/BiP promoter by the human nuclear factor CBF/NF-Y.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

BiP binding keeps ATF6 at bay.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Splicing: HACking into the unfolded-protein response

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Plasma cell differentiation requires the transcription factor XBP-1

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Up-regulation of the Ire1-mediated signaling molecule, Bip, in ischemic rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

c-Jun and the transcriptional control of neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Bcl-2 and Bcl-X(L) block thapsigargin-induced nitric oxide generation, c-Jun NH(2)-terminal kinase activity, and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Akt1 regulates a JNK scaffold during excitotoxic apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

c-Jun N-terminal protein kinase (JNK) 2/3 is specifically activated by stress, mediating c-Jun activation, in the presence of constitutive JNK1 activity in cerebellar neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Stress activated protein kinases, a novel family of mitogen-activated protein kinases, are heterogeneously expressed in the adult rat brain and differentially distributed from extracellular-signal-regulated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Peripheral axotomy induces long-term c-Jun amino-terminal kinase-1 activation and activator protein-1 binding activity by c-Jun and junD in adult rat dorsal root ganglia In vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Induction of interleukin-6 in axotomized sensory neurons

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Interleukin-1 activity in lesioned peripheral nerve

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Axonal transport of TNF-alpha in painful neuropathy: distribution of ligand tracer and TNF receptors

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Expression of interleukin-1 beta in rat dorsal root ganglia

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7 January 2021

Neurotrophic factors in regeneration

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Induction of Bip mRNA upon programmed cell death of differentiated PC12 cells as well as rat sympathetic neurons

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Axotomy increases the expression of glucose-regulated protein 78 kDa in rat facial nucleus

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Hypothermic treatment restores glucose regulated protein 78 (GRP78) expression in ischemic brain

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https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Stress-inducible transcription factor CHOP/gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Characterization of apoptosis-genes associated with NMDA mediated cell death in the adult rat retina

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Microarray analysis of hippocampal gene expression in global cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Up-regulation of genes involved in cellular stress and apoptosis in a rat model of hippocampal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Activation of gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Peroxidative stress selectively down-regulates the neuronal stress response activated under conditions of endoplasmic reticulum dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Abeta(1-42) and aluminum induce stress in the endoplasmic reticulum in rabbit hippocampus, involving nuclear translocation of gadd 153 and NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Manganese induces endoplasmic reticulum (ER) stress and activates multiple caspases in nigral dopaminergic neuronal cells, SN4741.

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Manganese(II) induces apoptotic cell death in NIH3T3 cells via a caspase-12-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS014341600200194X

7 January 2021

10.1016/S014341600200194X

Identifiers

DOI

1 reference

6 August 2017

1 reference